Zobrazeno 1 - 10 of 21 pro vyhledávání: '"Clara B. Martins"'
1
Akademický článek
Pd(II) and Pt(II) Trinuclear Chelates with Spermidine: Selective Anticancer Activity towards TNBC-Sensitive and -Resistant to Cisplatin
Autor: Martin Vojtek, Clara B. Martins, Raquel Ramos, Sara Gomes Duarte, Isabel M. P. L. V. O. Ferreira, Ana L. M. Batista de Carvalho, M. Paula M. Marques, Carmen Diniz
Publikováno v: Pharmaceutics, Vol 15, Iss 4, p 1205 (2023)
Triple-negative breast cancer (TNBC) is one of the most aggressive forms of breast cancer and constitutes 10–20% of all breast cancer cases. Even though platinum-based drugs such as cisplatin and carboplatin are effective in TNBC patients, their to
Externí odkaz: https://doaj.org/article/fb6cc0d587a2403d9939d9cd333fa882
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2
Akademický článek
A Non-Conventional Platinum Drug against a Non-Small Cell Lung Cancer Line
Autor: Jéssica D. Silva, Joana Marques, Inês P. Santos, Ana L. M. Batista de Carvalho, Clara B. Martins, Raquel C. Laginha, Luís A. E. Batista de Carvalho, Maria Paula M. Marques
Publikováno v: Molecules, Vol 28, Iss 4, p 1698 (2023)
A dinuclear Pt(II) complex with putrescine as bridging polyamine ligand ([Pt2Put2(NH3)4]Cl4) was synthesized and assessed as to its potential anticancer activity against a human non-small cell lung cancer line (A549), as well as towards non-cancer ce
Externí odkaz: https://doaj.org/article/5e6cb1fed73340e1926d752b51b97670
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3
Akademický článek
Evaluation of the Cytotoxic Effect of Pd2Spm against Prostate Cancer through Vibrational Microspectroscopies
Autor: Raquel C. Laginha, Clara B. Martins, Ana L. C. Brandão, Joana Marques, M. Paula M. Marques, Luís A. E. Batista de Carvalho, Inês P. Santos, Ana L. M. Batista de Carvalho
Publikováno v: International Journal of Molecular Sciences, Vol 24, Iss 3, p 1888 (2023)
Regarding the development of new antineoplastic agents, with a view to assess the selective antitumoral potential which aims at causing irreversible damage to cancer cells while preserving the integrity of their healthy counterparts, it is essential
Externí odkaz: https://doaj.org/article/4deded6d5b4a4ae9bd9a50ef68152994
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4
Akademický článek
Microalgae and Cyanobacteria Strains as Producers of Lipids with Antibacterial and Antibiofilm Activity
Autor: Virginio Cepas, Ignacio Gutiérrez-Del-Río, Yuly López, Saúl Redondo-Blanco, Yaiza Gabasa, María José Iglesias, Raquel Soengas, Andrés Fernández-Lorenzo, Sara López-Ibáñez, Claudio J. Villar, Clara B. Martins, Joana D. Ferreira, Mariana F. G. Assunção, Lília M. A. Santos, João Morais, Raquel Castelo-Branco, Mariana A. Reis, Vitor Vasconcelos, Fernando López-Ortiz, Felipe Lombó, Sara M. Soto
Publikováno v: Marine Drugs, Vol 19, Iss 12, p 675 (2021)
Lipids are one of the primary metabolites of microalgae and cyanobacteria, which enrich their utility in the pharmaceutical, feed, cosmetic, and chemistry sectors. This work describes the isolation, structural elucidation, and the antibiotic and anti
Externí odkaz: https://doaj.org/article/37bd843ada6145ac90241f4700aa9eaf
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5
Akademický článek
Preclinical Pharmacokinetics and Biodistribution of Anticancer Dinuclear Palladium(II)-Spermine Complex (Pd2Spm) in Mice
Autor: Martin Vojtek, Salomé Gonçalves-Monteiro, Edgar Pinto, Sára Kalivodová, Agostinho Almeida, Maria P. M. Marques, Ana L. M. Batista de Carvalho, Clara B. Martins, Helder Mota-Filipe, Isabel M. P. L. V. O. Ferreira, Carmen Diniz
Publikováno v: Pharmaceuticals, Vol 14, Iss 2, p 173 (2021)
Palladium-based compounds are regarded as potential analogs to platinum anticancer drugs with improved properties. The present study assessed the pharmacokinetics and biodistribution of a dinuclear palladium(II)-spermine chelate (Pd2Spm), which has p
Externí odkaz: https://doaj.org/article/39a942a359454135aacd465faf79219b
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6
Akademický článek
Inhibition of Bacterial and Fungal Biofilm Formation by 675 Extracts from Microalgae and Cyanobacteria
Autor: Virginio Cepas, Yuly López, Yaiza Gabasa, Clara B. Martins, Joana D. Ferreira, Maria J. Correia, Lília M.A. Santos, Flávio Oliveira, Vitor Ramos, Mariana Reis, Raquel Castelo-Branco, João Morais, Vitor Vasconcelos, Ian Probert, Emilie Guilloud, Mohamed Mehiri, Sara M. Soto
Publikováno v: Antibiotics, Vol 8, Iss 2, p 77 (2019)
Bacterial biofilms are complex biological systems that are difficult to eradicate at a medical, industrial, or environmental level. Biofilms confer bacteria protection against external factors and antimicrobial treatments. Taking into account that ab
Externí odkaz: https://doaj.org/article/97f06eed2899486fa7d63307c595f1c6
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7
Eustigmatophyte strains with potential interest in cancer prevention and treatment: partial chemical characterization and evaluation of cytotoxic and antioxidant activity
Autor: Lília M.A. Santos, Eugenia Gallardo, Clara B. Martins, Tiago Rosado, O Ferreira, Samuel Silvestre
Publikováno v: Biotechnology Letters. 43:1487-1502
The interest in bioactive compounds from microalgae is increasing since they have medicinal and nutritional areas. The present work aims to evaluate the potential pharmaceutical interest of extracts from three eustigmatophyte strains from the Coimbra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5d446c3ef76f58170a1aaad0f36ac7d0
https://doi.org/10.1007/s10529-021-03122-0
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8
Chemotaxonomic Profiling Through NMR 1
Autor: Maria João Correia, Fernando López Ortiz, Lília M.A. Santos, Clara B. Martins, María José Iglesias, Raquel G. Soengas, Joana D. Ferreira
Publikováno v: Journal of Phycology. 56:521-539
A metabolite screening of cyanobacteria was performed by nuclear magnetic resonance (NMR) analysis of the soluble material obtained through sequential extraction of the biomass with three different extractive ability solvents (hexane, ethyl acetate,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce26d11151a3d8e6a8a23efbb9ec673f
https://doi.org/10.1111/jpy.12959
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10
Microalgae and Cyanobacteria Strains as Producers of Lipids with Antibacterial and Antibiofilm Activity
Autor: Mariana Reis, Raquel Castelo-Branco, Vitor Vasconcelos, Felipe Lombó, Joana D. Ferreira, Lília M.A. Santos, Raquel G. Soengas, María José Iglesias, Clara B. Martins, Virginio Cepas, Sara López-Ibáñez, Yuly López, Mariana F.G. Assunção, Andrés Fernández-Lorenzo, Sara M. Soto, Saúl Redondo-Blanco, Ignacio Gutiérrez-del-Río, João Morais, Claudio J. Villar, Fernando López-Ortiz, Yaiza Gabasa
Publikováno v: Marine Drugs
Marine Drugs, Vol 19, Iss 675, p 675 (2021)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
riUAL. Repositorio Institucional de la Universidad de Almería
Universidad de Almería
Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Marine Drugs; Volume 19; Issue 12; Pages: 675
This research was funded by the European Union’s Horizon 2020 research and innovation program under grant agreement no. 634588 (NOMORFILM). We thank Programa Severo Ochoa de Ayudas Predoctorales para la investigación y docencia from Principado de
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fcd42563c2ac5a5d31e3d8cf1b2dc0a
http://europepmc.org/articles/PMC8709229
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