Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Clara Armengol"'
Autor:
Adelaide A. Hebert, Carsten Flohr, H. Chih-ho Hong, Alan D. Irvine, Evangeline Pierce, Hany Elmaraghy, Sreekumar Pillai, Zach Dawson, Sherry Chen, Clara Armengol, Elaine Siegfried, Stephan Weidinger
Publikováno v:
Journal of Dermatological Treatment, Vol 35, Iss 1 (2024)
AbstractBackground Lebrikizumab, a high-affinity monoclonal antibody targeting IL-13, previously demonstrated clinical efficacy in three randomized, double-blind, placebo-controlled Phase 3 trials that included adults and adolescents with moderate-to
Externí odkaz:
https://doaj.org/article/b5ef1bb85af14e1fb68d15d4099d7b35
Autor:
Amy S. Paller, Carsten Flohr, Lawrence F. Eichenfield, Alan D. Irvine, Jamie Weisman, Jennifer Soung, Ana Pinto Correia, Chitra R. Natalie, Claudia Rodriguez Capriles, Evangeline Pierce, Sarah Reifeis, Renata Gontijo Lima, Clara Armengol Tubau, Vivian Laquer, Stephan Weidinger
Publikováno v:
Dermatology and Therapy, Vol 13, Iss 7, Pp 1517-1534 (2023)
Abstract Introduction Atopic dermatitis (AD) is a chronic inflammatory skin disorder with limited treatment options for adolescents with moderate-to-severe disease. Lebrikizumab, a monoclonal antibody targeting interleukin (IL)-13, demonstrated clini
Externí odkaz:
https://doaj.org/article/f1994888427840c4b87a98813eff0651
Akademický článek
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Publikováno v:
Comp Med
Currently, metabolic cages (MC) are the only way to achieve serial sampling of urine and feces in rodents. However, the use of this caging creates a dramatic change from an animal's usual microenvironment. Here we sought to examine the effect of MC o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12157ef209d2742abea0268b6d62ebb8
https://doi.org/10.30802/aalas-cm-22-000026
https://doi.org/10.30802/aalas-cm-22-000026
Autor:
Montserrat Miralpeix, Montse Erra, Stephane Paris, Elena Calama, Francisco Javier Bernal, Jordi Gràcia, Martin D. Lehner, María Domínguez, Joan Taltavull, Salome Soria, Mónica Bravo, Clara Armengol, Begoña Hernández, Juan Francisco Caturla, Judit Cabedo, M Sabate, Angelique Gréco
Publikováno v:
ACS Medicinal Chemistry Letters. 8:118-123
The delta isoform of the phosphatidylinositol 3-kinase (PI3Kδ) has been shown to have an essential role in specific immune cell functions and thus represents a potential therapeutic target for autoimmune and inflammatory diseases. Herein, the optimi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44822b10139accb74df05897b5883555
https://doi.org/10.1021/acsmedchemlett.6b00438
https://doi.org/10.1021/acsmedchemlett.6b00438
Discovery of a novel class of zwitterionic, potent, selective and orally active S1P1 direct agonists
Autor:
Gema Tarrasón, Nuria Godessart, Marta Mir, Clara Armengol, Mònica Córdoba, Dolors Vilella, Daniel Casals, Manel López, Victor Segarra, Teresa Doménech, Imma Moreno, M Sabate, Nuria Aguilar, Pedro M. Grima, María Domínguez, Laia Esteban
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:7672-7676
Amido-1,3,4-thiadiazoles have been identified as a novel structural class of potent and selective sphingosine-1-phosphate receptor subtype 1 agonists. Starting from a micromolar HTS hit with the help of an in-house homology model, robust structural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::267ca19860dca563219d7e83fee9d6af
https://doi.org/10.1016/j.bmcl.2012.09.110
https://doi.org/10.1016/j.bmcl.2012.09.110
Autor:
Miriam Andrés, Peter Eichhorn, Richard E. Roberts, Vicente García-González, Clara Armengol, Mónica Bravo, Rosa López, Montserrat Miralpeix, Marta Calbet
Publikováno v:
Pharmacological research. 111
The chemoattractant receptor-homologous molecule expressed on T-helper type 2 cells (CRTh2) is a G protein-coupled receptor expressed on the leukocytes most closely associated with asthma and allergy like eosinophils, mast cells, Th2-lymphocytes and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc60c53aaa02528d9e680b0922c975f
https://pubmed.ncbi.nlm.nih.gov/27317944
https://pubmed.ncbi.nlm.nih.gov/27317944
Autor:
L Mendes-Jorge, Verònica Melgarejo, Alfonso Rodríguez-Baeza, Marc Navarro, Mariana Luppo, Ana Carretero, Jesús Ruberte, Cristina Llombart, Clara Armengol, David Ramos, Víctor Nacher
Publikováno v:
Journal of Anatomy. 215:280-291
The periphery of the vitreous body contains a population of cells termed hyalocytes. Despite the existence for more than one century of publications devoted to the pecten oculi, a convoluted coil of blood vessels that seems to be the primary source o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5948d643dee7e588ca990410a57716a4
https://doi.org/10.1111/j.1469-7580.2009.01117.x
https://doi.org/10.1111/j.1469-7580.2009.01117.x
Publikováno v:
Journal of Anatomy. 210:98-111
A selection of lectins were used to study changes in the distribution of sugar residues in primordial germ cells (PGCs) during gonadal colonization and differentiation. Although the cytochemical characteristics of PGCs have been described in the chic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d69b924b35c75c1b5365909c9eacdcf6
https://doi.org/10.1111/j.1469-7580.2006.00668.x
https://doi.org/10.1111/j.1469-7580.2006.00668.x
Autor:
Li-ya Ye, Ji-xiao Niu, Georges E. Grau, Jean-Charles Fruchart, Clarisse Cuaz-Pérolin, Marie-Christine Hamaide, Changqian Wang, Mohamed Naceur Slimane, María Sofía Giménez, J.M. Gosline, Verónica A. Vega, Lian-Qiu Wu, Víctor Nacher, G. Larigauderie, Alfonso Rodríguez, Cristina Llombart, Imen Jguirim, Peter Krenek, Yu-ling Xin, Mustapha Rouis, Nicole Morel, Christophe Furman, Zhihua Yang, Clara Armengol, Immaculada Herrero-Fresneda, M. John Chapman, Jinning Lou, Meng Jiang, Maurice Wibo, Li Gao, Taylor B. Guo, Ben He, Guang-jin Zhu, Fanny Zirulnik, Feng Gu, Laura V. Gatica, Qin Shao, Awatef Jlassi, Jesús Ruberte, Hafid Mezdour, Binyao Wang, Marc Navarro, Huahua Fan, Yan Liu, Martine Moreau, Liliana Oliveros, Ana Carretero, Wenjian Zhang, M.A. Lillie, Eduard Ayuso
Publikováno v:
Journal of Vascular Research. 43:533-580
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a240fa5b411cbf40233eacfd1799c35
https://doi.org/10.1159/000096075
https://doi.org/10.1159/000096075