Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Clara Apicella"'
Autor:
Clara Apicella, Camino S. M. Ruano, Basky Thilaganathan, Asma Khalil, Veronica Giorgione, Géraldine Gascoin, Louis Marcellin, Cassandra Gaspar, Sébastien Jacques, Colin E. Murdoch, Francisco Miralles, Céline Méhats, Daniel Vaiman
Publikováno v:
Cells, Vol 12, Iss 4, p 578 (2023)
In this study, we attempted to find genetic variants affecting gene expression (eQTL = expression Quantitative Trait Loci) in the human placenta in normal and pathological situations. The analysis of gene expression in placental diseases (Pre-eclamps
Externí odkaz:
https://doaj.org/article/863db01e1ecc47a8854af3f05546c663
Autor:
Clara Apicella, Camino S. M. Ruano, Sébastien Jacques, Géraldine Gascoin, Céline Méhats, Daniel Vaiman, Francisco Miralles
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
A bioinformatics screen for non-coding genes was performed from microarrays analyzing on the one hand trophoblast fusion in the BeWo cell model, and on the other hand, placental diseases (preeclampsia and Intra-Uterine Growth Restriction). Intersecti
Externí odkaz:
https://doaj.org/article/5803d071eb704656885b23ac93a52eee
Autor:
Samprikta Manna, Camino S. M. Ruano, Jana-Charlotte Hegenbarth, Daniel Vaiman, Shailendra Gupta, Fergus P. McCarthy, Céline Méhats, Cathal McCarthy, Clara Apicella, Julia Scheel
Publikováno v:
Antioxidants, Vol 11, Iss 3, p 585 (2022)
Oxidative stress is associated with a myriad of diseases including pregnancy pathologies with long-term cardiovascular repercussions for both the mother and baby. Aberrant redox signalling coupled with deficient antioxidant defence leads to chronic m
Externí odkaz:
https://doaj.org/article/d555ca231d78493d8eaf89c7bb5ea211
Autor:
Aurélien Ducat, Betty Couderc, Anthony Bouter, Louise Biquard, Rajaa Aouache, Bruno Passet, Ludivine Doridot, Marie-Benoîte Cohen, Pascale Ribaux, Clara Apicella, Irène Gaillard, Sophia Palfray, Yulian Chen, Alexandra Vargas, Amélie Julé, Léo Frelin, Julie Cocquet, Camino Ruano San Martin, Sébastien Jacques, Florence Busato, Jorg Tost, Céline Méhats, Paul Laissue, Jean-Luc Vilotte, Francisco Miralles, Daniel Vaiman
Publikováno v:
iScience, Vol 23, Iss 5, Pp - (2020)
Summary: STOX1 is a transcription factor involved in preeclampsia and Alzheimer disease. We show that the knock-down of the gene induces rather mild effect on gene expression in trophoblast cell lines (BeWo). We identified binding sites of STOX1 shar
Externí odkaz:
https://doaj.org/article/b54fcc60ee1d4939917d4e09e86f70c3
Publikováno v:
International journal of molecular sciences. 23(24)
CD24 is a mucin-like immunosuppressing glycoprotein whose levels increase during pregnancy and decrease in the syncytio- and cytotrophoblasts in early and preterm preeclampsia. We used two modified cell lines that mimic in vitro features of preeclamp
Autor:
S. Nashitha Kabir, Jasmeet S. Reyat, Antony J. Workman, Priyanka Saxena, Dannie Fobian, Davor Pavlovic, Larissa Fabritz, Clara Apicella, Stefan M. Kuhlmann, Godfrey L. Smith, Paulus Kirchhof, Molly O’Reilly, Andrew P. Holmes, Fahima Syeda, Suranjana Gupta, Christopher O’Shea
Publikováno v:
Heart Rhythm. 18:1212-1220
Background Although atrial fibrillation ablation is increasingly used for rhythm control therapy, antiarrhythmic drugs (AADs) are commonly used, either alone or in combination with ablation. The effectiveness of AADs is highly variable. Previous work
Autor:
Agathe Lermant, Shawn Cottrill, Clara Apicella, Celine Metas, Daniel Vaiman, Colin E. Murdoch
Publikováno v:
Free Radical Biology and Medicine. 201:60
Autor:
Sian O' Brien, Andrew P. Holmes, Daniel M. Johnson, S. Nashitha Kabir, Christopher O' Shea, Molly O' Reilly, Adelisa Avezzu, Jasmeet S. Reyat, Amelia W. Hall, Clara Apicella, Patrick T. Ellinor, Steven Niederer, Nathan R. Tucker, Larissa Fabritz, Paulus Kirchhof, Davor Pavlovic
Atrial fibrillation (AF) affects over 1% of the population and is a leading cause of stroke and heart failure in the elderly. A feared side effect of sodium channel blocker therapy, ventricular pro-arrhythmia, appears to be relatively rare in patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::978c50e204b5bb0d3afc935e4259b287
http://oro.open.ac.uk/81833/1/OBrien_et_al_Atrial_vs_Ventricular_Sodium_JMCC_13_01_2022.pdf
http://oro.open.ac.uk/81833/1/OBrien_et_al_Atrial_vs_Ventricular_Sodium_JMCC_13_01_2022.pdf
Publikováno v:
Placenta. 112:e84-e85
Publikováno v:
Human Genetics