Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Clara, Reglero"'
Autor:
Lucia Morgado-Palacin, Jessie A. Brown, Thomas F. Martinez, Juana M. Garcia-Pedrero, Farhad Forouhar, S. Aidan Quinn, Clara Reglero, Joan Vaughan, Yasamin Hajy Heydary, Cynthia Donaldson, Sandra Rodriguez-Perales, Eva Allonca, Rocio Granda-Diaz, Agustin F. Fernandez, Mario F. Fraga, Arianna L. Kim, Jorge Santos-Juanes, David M. Owens, Juan P. Rodrigo, Alan Saghatelian, Adolfo A. Ferrando
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
TINCR encodes a p53-regulated ubiquitin-like microprotein expressed in stratified epithelia. Tincr loss promotes UVB-induced skin carcinogenesis in mice and deletions and mutations in human squamous cell carcinoma support a tumor suppressor role.
Externí odkaz:
https://doaj.org/article/99397db4eb4344f19ba418b654b42f08
Autor:
Adolfo A. Ferrando, Teresa Palomero, Brent R. Stockwell, Liang Tong, Mignon L. Loh, Julie M. Gastier-Foster, Cindy Ma, Hannah I. Miller, Robert Albero, Wen-Hsuan W. Lin, Anouchka P. Laurent, Farhad Forouhar, Arie Zask, Chelsea L. Dieck, Clara Reglero
Low-intensity maintenance therapy with 6-mercaptopurine (6-MP) limits the occurrence of acute lymphoblastic leukemia (ALL) relapse and is central to the success of multiagent chemotherapy protocols. Activating mutations in the 5′-nucleotidase cytos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::724879d7d04346e020351611ac3bd15b
https://doi.org/10.1158/2159-8290.c.6549792.v1
https://doi.org/10.1158/2159-8290.c.6549792.v1
Autor:
Adolfo A. Ferrando, Teresa Palomero, Brent R. Stockwell, Liang Tong, Mignon L. Loh, Julie M. Gastier-Foster, Cindy Ma, Hannah I. Miller, Robert Albero, Wen-Hsuan W. Lin, Anouchka P. Laurent, Farhad Forouhar, Arie Zask, Chelsea L. Dieck, Clara Reglero
Supplementary Figure from Pharmacologic Inhibition of NT5C2 Reverses Genetic and Nongenetic Drivers of 6-MP Resistance in Acute Lymphoblastic Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b33ea786d0742501a13c41a69c7ef44
https://doi.org/10.1158/2159-8290.22542057
https://doi.org/10.1158/2159-8290.22542057
Autor:
Adolfo A. Ferrando, Teresa Palomero, Brent R. Stockwell, Liang Tong, Mignon L. Loh, Julie M. Gastier-Foster, Cindy Ma, Hannah I. Miller, Robert Albero, Wen-Hsuan W. Lin, Anouchka P. Laurent, Farhad Forouhar, Arie Zask, Chelsea L. Dieck, Clara Reglero
Supplementary Table from Pharmacologic Inhibition of NT5C2 Reverses Genetic and Nongenetic Drivers of 6-MP Resistance in Acute Lymphoblastic Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b1347dacb24bff35508410f812e7e2
https://doi.org/10.1158/2159-8290.22542048.v1
https://doi.org/10.1158/2159-8290.22542048.v1
Publikováno v:
Cells, Vol 10, Iss 4, p 729 (2021)
The timing of centrosome separation and the distance moved apart influence the formation of the bipolar spindle, affecting chromosome stability. Epidermal growth factor receptor (EGFR) signaling induces early centrosome separation through downstream
Externí odkaz:
https://doaj.org/article/412084e2078e4fb98db1d692a2ff1121
Autor:
Laura Nogués, Clara Reglero, Verónica Rivas, Alicia Salcedo, Vanesa Lafarga, Maria Neves, Paula Ramos, Marta Mendiola, Alberto Berjón, Kostas Stamatakis, Xiao Zhen Zhou, Kun Ping Lu, David Hardisson, Federico Mayor Jr., Petronila Penela
Publikováno v:
EBioMedicine, Vol 13, Iss C, Pp 132-145 (2016)
In addition to oncogenic drivers, signaling nodes can critically modulate cancer-related cellular networks to strength tumor hallmarks. We identify G-protein-coupled receptor kinase 2 (GRK2) as a relevant player in breast cancer. GRK2 is up-regulated
Externí odkaz:
https://doaj.org/article/b1dfca60da144d5db201e71b0938f759
Autor:
Clara Reglero, Chelsea L. Dieck, Arie Zask, Farhad Forouhar, Anouchka P. Laurent, Wen-Hsuan W. Lin, Robert Albero, Hannah I. Miller, Cindy Ma, Julie M. Gastier-Foster, Mignon L. Loh, Liang Tong, Brent R. Stockwell, Teresa Palomero, Adolfo A. Ferrando
Publikováno v:
Cancer Discov
Low-intensity maintenance therapy with 6-mercaptopurine (6-MP) limits the occurrence of acute lymphoblastic leukemia (ALL) relapse and is central to the success of multiagent chemotherapy protocols. Activating mutations in the 5′-nucleotidase cytos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::993ed9dee959ca6c9f9a09886a4b291b
https://europepmc.org/articles/PMC9633388/
https://europepmc.org/articles/PMC9633388/
Autor:
Manuel Torres-Diz, Andrei Thomas-Tikhonenko, Clara Reglero, Adolfo Ferrando, Catherine D Falkenstein, Sarah K Tasian, Priyanka Sehgal, Zhiwei Ang, Yoseph Barash, Caleb Radens
Publikováno v:
Blood. 140:3264-3265
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c71c8e01ea3aa05e4d727b90b8101ce
https://doi.org/10.1182/blood-2022-167006
https://doi.org/10.1182/blood-2022-167006
GATA3-Controlled Nucleosome Eviction Drives MYC Enhancer Activity in T-cell Development and Leukemia
Autor:
Ramya Raviram, Clara Reglero, Francesco Gavino Brundu, Raul Rabadan, Pedro P. Rocha, Jose R. Cortes, Alexander Y. Yang, Daniel Herranz, S. Aidan Quinn, Jules P.P. Meijerink, Pablo Pérez-Durán, Valentina Cordo, Agnieszka A. Wendorff, Francesca Gianni, Silvia Alvarez, Marissa Rashkovan, Robert Albero, Adolfo A. Ferrando, Devya Gurung, Laura Belver, Anisha J. Cooke
Publikováno v:
Cancer Discovery. 9:1774-1791
Long-range enhancers govern the temporal and spatial control of gene expression; however, the mechanisms that regulate enhancer activity during normal and malignant development remain poorly understood. Here, we demonstrate a role for aberrant chroma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::561896251e36b0020d1af41cb92deed0
https://doi.org/10.1158/2159-8290.cd-19-0471
https://doi.org/10.1158/2159-8290.cd-19-0471
Publikováno v:
Cells
Volume 10
Issue 4
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cells, Vol 10, Iss 729, p 729 (2021)
Volume 10
Issue 4
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cells, Vol 10, Iss 729, p 729 (2021)
The timing of centrosome separation and the distance moved apart influence the formation of the bipolar spindle, affecting chromosome stability. Epidermal growth factor receptor (EGFR) signaling induces early centrosome separation through downstream
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::783f362abb6efb0aa12c759dd6c413e9