Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Clara, Braian"'
Publikováno v:
Journal of Innate Immunity, Pp 1-1 (2023)
Epigenetic reprogramming of innate immune cells by β-glucan in a process called trained immunity, leads to an enhanced host response to a secondary infection. β-glucans are structural components of plants, algae, fungi and bacteria and thus recogni
Externí odkaz:
https://doaj.org/article/f76b1a023105496680fa111c545a9e4b
Autor:
Venkata R. Parasa, Jagadeeswara R. Muvva, Jeronimo F. Rose, Clara Braian, Susanna Brighenti, Maria Lerm
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Granulomas are hallmarks of pulmonary tuberculosis (TB) and traditionally viewed as host-protective structures. However, recent evidence suggest that Mycobacterium tuberculosis (Mtb) uses its virulence factors to stimulate the formation of granuloma.
Externí odkaz:
https://doaj.org/article/24eea16891c3412da0d41a5630e440da
Autor:
Sadaf Kalsum, Clara Braian, Valerie A. C. M. Koeken, Johanna Raffetseder, Margaretha Lindroth, Reinout van Crevel, Maria Lerm
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
The causative agent of tuberculosis, Mycobacterium tuberculosis, shares several characteristics with organisms that produce biofilms during infections. One of these is the ability to form tight bundles also known as cords. However, little is known of
Externí odkaz:
https://doaj.org/article/8e15d43527b3409896c63cb29be79174
The mechanism of protection of the only approved tuberculosis (TB) vaccine, Bacillus Calmette Guérin (BCG) is poorly understood. In recent years, epigenetic modifications induced by BCG have been demonstrated to reflect a state of trained immunity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85747f210f3f5501e6d09b325df5833f
https://doi.org/10.21203/rs.3.rs-1157082/v1
https://doi.org/10.21203/rs.3.rs-1157082/v1
Autor:
Eva Kristin Danielsson, Maria Lerm, Jyotirmoy Das, Nina Idh, Isabelle Pehrson, Clara Braian, Jakob Paues, Lovisa Karlsson, Blanka Andersson
The mechanism of protection of the only approved tuberculosis (TB) vaccine, Bacillus Calmette Guérin (BCG) is poorly understood. In recent years, epigenetic modifications induced by BCG have been demonstrated to reflect a state of trained immunity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dca3d9a90c641a72fdae98b6b716836c
https://doi.org/10.1101/2021.09.01.21262945
https://doi.org/10.1101/2021.09.01.21262945
Autor:
Clara Braian
Publikováno v:
Linköping University Medical Dissertations ISBN: 9789179297589
Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis, and the cause of 1.5 million deaths in 2018. During a pulmonary TB infection, the bacterium reaches th ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9b0012bc0d99ce26476ff08bb0a236e
https://doi.org/10.3384/diss.diva-170203
https://doi.org/10.3384/diss.diva-170203
Autor:
Charlotta Sundin, Sadaf Kalsum, Stina Berglund Fick, Maria Lerm, Isabel Edström, Christer Larsson, Mikael Elofsson, Hasan Tükenmez, Clara Braian, Ramesh Ummanni
The effect of corticosteroids on human physiology is complex and their use in tuberculosis patients remains controversial. In a high-throughput screening approach designed to discover virulence inhibitors, several corticosteroids were found to preven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d58a7c175a3e9b2aec4d699ebdd06b
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-157508
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-157508
Autor:
Tom van der Poll, Alexander Hecht, Sabine Lehne, Georges Herbein, Anna Linnér, Berenice Barajas, Sander de Kivit, Linette E M Willemsen, Haibo Zhou, James C. Hurley, Sarah A. Horst, Andre E. Nel, Ning Li, Vincent Di Martino, Eva Medina, Steven M. Opal, Erin M. Wahle, Oliver Goldmann, Wasim Abbas, Arne Egesten, William D. Bennett, Aletta D. Kraneveld, Francis J. Miller, David B. Peden, Olle Stendahl, John C. Lay, Steven M. Varga, Neil E. Alexis, Claudia Höltje, Laura C. Whitmore, Sandrine Florquin, Marc A. Williams, Kelli L. Goss, Leon Grayfer, Marianne Geiser, Meiying Wang, Yvette van Kooyk, Amit Kumar, Valentin Hogea, Kashif Aziz Khan, Johan Garssen, Clara Braian, Audrey Varin, Léon M.J. Knippels, Tarah T. Colaizy, Cornelis van 't Veer, Satz Mengensatzproduktion, Constantinos Sioutas, Heiko Herwald, Regina de Beer, Jessica G. Moreland, Jacques Robert, Paola M. Boggiatto, Brieanna M. Hilkin, Andreas Beineke, Xiaoyan Wang, Druckerei Stückle, Alex F. de Vos, Ahmed Achouiti, Anna Norrby-Teglund, Isabelle Dichamp
Publikováno v:
Journal of Innate Immunity. 5:I-IV
Publikováno v:
Journal of Innate Immunity. 5:591-602
Neutrophils activated by Mycobacterium tuberculosis (Mtb) form neutrophil extracellular traps (NETs), containing DNA and several biologically active cytosolic and granular proteins. These NETs may assist in the innate immune defense against different
Publikováno v:
Journal of Visualized Experiments : JoVE
Tuberculosis (TB) still holds a major threat to the health of people worldwide, and there is a need for cost-efficient but reliable models to help us understand the disease mechanisms and advance the discoveries of new treatment options. In vitro cel