Genetic suppression of agrin reduces mania-like behavior in Na⁺, K⁺-ATPase α3 mutant mice.

Autor: Kirshenbaum, G. S.^1,2, Clapcote, S. J.³, Petersen, J.⁴, Vilsen, B.⁴, Ralph, M. R.⁵, Roder, J. C.^1,2,6

Publikováno v: Genes, Brain & Behavior. Jun2012, Vol. 11 Issue 4, p436-443. 8p. 3 Graphs.

Synaptic modulators Nrxn1 and Nrxn3 are disregulated in a Disc1 mouse model of schizophrenia.

Autor: Brown, S. M.¹, Clapcote, S. J.², Millar, J. K.¹, Torrance, H. S.¹, Anderson, S. M.¹, Walker, R.¹, Rampino, A.¹, Roder, J. C.³, Thomson, P. A.⁴, Porteous, D. J.⁴, Evans, K. L.⁴

Publikováno v: Molecular Psychiatry. Jun2011, Vol. 16 Issue 6, p585-587. 3p. 1 Graph.

Disrupted in schizophrenia 1 and phosphodiesterase 4B: towards an understanding of psychiatric illness

Autor: Millar, J. K., Mackie, S., Clapcote, S. J., Murdoch, H., Pickard, B. S., Christie, S., Muir, W. J., Blackwood, D. H., Roder, J. C., Houslay, M. D., Porteous, D. J.

Publikováno v: Millar, J K, Mackie, S, Clapcote, S J, Murdoch, H, Pickard, B S, Christie, S, Muir, W J, Blackwood, D H, Roder, J C, Houslay, M D & Porteous, D J 2007, ' Disrupted in schizophrenia 1 and phosphodiesterase 4B: towards an understanding of psychiatric illness ', Journal of Physiology, vol. 584, no. Pt 2, pp. 401-405 . https://doi.org/10.1113/jphysiol.2007.140210

Disrupted in schizophrenia 1 (DISC1) is one of the most convincing genetic risk factors for major mental illness identified to date. DISC1 interacts directly with phosphodiesterase 4B (PDE4B), an independently identified risk factor for schizophrenia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3094::53505cb7b5dfb5badff38304674e0be4
https://www.pure.ed.ac.uk/ws/files/9104058/Disrupted_in_schizophrenia_1_and_phosphodiesterase_4B.pdf

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