Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Claire de la Cova"'
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 12, Pp 4707-4712 (2020)
Externí odkaz:
https://doaj.org/article/cfb4d62263cd48a2972a86284bf2efda
Publikováno v:
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 10, Iss 12, Pp 4707-4712 (2020)
G3: Genes, Genomes, Genetics, Vol 10, Iss 12, Pp 4707-4712 (2020)
The process of apoptosis in epithelia involves activation of caspases, delamination of cells, and degradation of cellular components. Corpses and cellular debris are then rapidly cleared from the tissue by phagocytic blood cells. In studies of the Dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e77e0b20b0e9e957a08aeeaaa6fdaa
https://doi.org/10.1534/g3.120.401800
https://doi.org/10.1534/g3.120.401800
Publikováno v:
Development.
Activation of a canonical EGFR-Ras-Raf-ERK cascade initiates patterning of multipotent Vulval Precursor Cells (VPCs) of C. elegans. We previously showed that this pathway includes a negative-feedback component in which MPK-1/ERK activity targets the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e100a545d5b89eeee4886147690f1328
https://doi.org/10.1242/dev.195941
https://doi.org/10.1242/dev.195941
Autor:
Laura A. Johnston, Nanami Senoo-Matsuda, Marcello Ziosi, Paola Bellosta, Catarina M. Quinzii, D. Christine Wu, Claire de la Cova
Publikováno v:
Cell Metabolism. 19:470-483
SummaryIn growing tissues, cell fitness disparities can provoke interactions that promote stronger cells at the expense of the weaker in a process called cell competition. The mechanistic definition of cell fitness is not understood, nor is it unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e499b4f7b25d1f4ff2a764d542927d
https://doi.org/10.1016/j.cmet.2014.01.012
https://doi.org/10.1016/j.cmet.2014.01.012
Autor:
Claire de la Cova, Iva Greenwald
Publikováno v:
Genes & Development. 26:2524-2535
The conserved E3 ubiquitin ligase component named SEL-10 in Caenorhabditis elegans and Fbw7 in mammals targets substrates for ubiquitin-mediated degradation through a high-affinity binding site called a Cdc4 phosphodegron (CPD). As many known substra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c4c65e614a41fdb38dbd98d0ca8c684
https://doi.org/10.1101/gad.203703.112
https://doi.org/10.1101/gad.203703.112
Autor:
Laura A. Johnston, Claire de la Cova
Publikováno v:
Seminars in Cancer Biology. 16:303-312
The Myc transcription factor regulates fundamental processes in a cell's life: its growth, division, and survival. Myc is conserved throughout metazoan phyla, and its identification in the fruit fly, Drosophila melanogaster has led to new insights in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3df45930773aa69241ffdf16448f5c6
https://doi.org/10.1016/j.semcancer.2006.07.010
https://doi.org/10.1016/j.semcancer.2006.07.010
Publikováno v:
Developmental Cell. 42:542-553.e4
Kinase translocation reporters (KTRs) are genetically encoded fluorescent activity sensors that convert kinase activity into a nucleocytoplasmic shuttling equilibrium for visualizing single-cell signaling dynamics. Here, we adapt the first-generation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6840ca645d4833bf61ef8481ef6c63f
https://doi.org/10.1016/j.devcel.2017.07.014
https://doi.org/10.1016/j.devcel.2017.07.014
Experiments in both vertebrates and invertebrates have illustrated the competitive nature of growth and led to the idea that competition is a mechanism of regulating organ and tissue size. We have assessed competitive interactions between cells in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c91c1038d6b5d6b4a0648d813727651
https://www.zora.uzh.ch/id/eprint/741/
https://www.zora.uzh.ch/id/eprint/741/
