Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Claire Y.-H. Huang"'
Autor:
Whitney R. Baldwin, Holli A. Giebler, Janae L. Stovall, Ginger Young, Kelly J. Bohning, Hansi J. Dean, Jill A. Livengood, Claire Y.-H. Huang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Here the authors generate a live-attenuated Zika vaccine based on a clinically proven dengue virus serotype-2 vaccine backbone and show that one dose protects mice and non-human primates from Zika virus infection.
Externí odkaz:
https://doaj.org/article/b8778b7cdf1e454aa4f4bbc9276e3404
Genetic Adaptation by Dengue Virus Serotype 2 to Enhance Infection of Aedes aegypti Mosquito Midguts
Publikováno v:
Viruses, Vol 14, Iss 7, p 1569 (2022)
Dengue viruses (DENVs), serotypes 1–4, are arthropod-borne viruses transmitted to humans by mosquitoes, primarily Aedes aegypti. The transmission cycle begins when Ae. aegypti ingest blood from a viremic human and the virus infects midgut epithelia
Externí odkaz:
https://doaj.org/article/eb6e14df614b47c3af4df3df0f058344
Publikováno v:
New England Journal of Medicine. 388:1633-1636
Autor:
Rebecca Salgado, Seth A. Hawks, Francesca Frere, Ana Vázquez, Claire Y.-H. Huang, Nisha K. Duggal
Publikováno v:
Viruses, Vol 13, Iss 12, p 2352 (2021)
West Nile virus (WNV) and Usutu virus (USUV) are mosquito-borne flaviviruses that can cause neuroinvasive disease in humans. WNV and USUV circulate in both Africa and Europe and are closely related. Due to antigenic similarity, WNV-specific antibodie
Externí odkaz:
https://doaj.org/article/e0390629ebbe47868f4fbf44f1ac0b2b
Autor:
Payal D Maharaj, Stanley A Langevin, Bethany G Bolling, Christy C Andrade, Xavier A Engle, Wanichaya N Ramey, Angela Bosco-Lauth, Richard A Bowen, Todd A Sanders, Claire Y-H Huang, William K Reisen, Aaron C Brault
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 7, p e0007473 (2019)
The N-linked glycosylation motif at amino acid position 154-156 of the envelope (E) protein of West Nile virus (WNV) is linked to enhanced murine neuroinvasiveness, avian pathogenicity and vector competence. Naturally occurring isolates with altered
Externí odkaz:
https://doaj.org/article/c074d38fd0b049d9a322a42893c3e9d0
Autor:
Elizabeth A Dietrich, Stanley A Langevin, Claire Y-H Huang, Payal D Maharaj, Mark J Delorey, Richard A Bowen, Richard M Kinney, Aaron C Brault
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 8, p e0004938 (2016)
West Nile virus (WNV) replicates in a wide variety of avian species, which serve as reservoir and amplification hosts. WNV strains isolated in North America, such as the prototype strain NY99, elicit a highly pathogenic response in certain avian spec
Externí odkaz:
https://doaj.org/article/763bbd6c9ec745b2b45fd8630a2f4df5
Autor:
Mars Stone, Karen L. Boroughs, Brad J. Biggerstaff, Kimberly M. Anderson, Kalanthe Horiuchi, Amanda E. Calvert, Michael P. Busch, Yee Tsuey Ong, Graham Simmons, Claire Y.-H. Huang
Publikováno v:
J Clin Microbiol
Dengue viruses (DENV) and Zika virus (ZIKV) are related mosquito-borne flaviviruses with similar disease manifestations, vector ecologies, and geographic ranges. The ability to differentiate these viruses serologically is vital due to the teratogenic
Autor:
Ana Vázquez, Claire Y.-H. Huang, Rebecca M Salgado, Francesca Frere, Seth A. Hawks, Nisha K. Duggal
Publikováno v:
Repisalud
Instituto de Salud Carlos III (ISCIII)
Viruses; Volume 13; Issue 12; Pages: 2352
Viruses
Viruses, Vol 13, Iss 2352, p 2352 (2021)
Instituto de Salud Carlos III (ISCIII)
Viruses; Volume 13; Issue 12; Pages: 2352
Viruses
Viruses, Vol 13, Iss 2352, p 2352 (2021)
West Nile virus (WNV) and Usutu virus (USUV) are mosquito-borne flaviviruses that can cause neuroinvasive disease in humans. WNV and USUV circulate in both Africa and Europe and are closely related. Due to antigenic similarity, WNV-specific antibodie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230a3fd10abd5b10075aa2b2a95c969b
http://hdl.handle.net/20.500.12105/14389
http://hdl.handle.net/20.500.12105/14389
Autor:
Claire Y-H Huang, Richard M Kinney, Jill A Livengood, Bethany Bolling, John J Arguello, Betty E Luy, Shawn J Silengo, Karen L Boroughs, Janae L Stovall, Akundi P Kalanidhi, Aaron C Brault, Jorge E Osorio, Dan T Stinchcomb
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 5, p e2243 (2013)
We have developed a manufacturing strategy that can improve the safety and genetic stability of recombinant live-attenuated chimeric dengue vaccine (DENVax) viruses. These viruses, containing the pre-membrane (prM) and envelope (E) genes of dengue se
Externí odkaz:
https://doaj.org/article/f4fd186079c94a3b8c24a3a99d2d23a7
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 97:1423-1427
Recombinant live-attenuated chimeric tetravalent dengue vaccine viruses, TDV-1, -2, -3, and -4, contain the premembrane and envelope genes of dengue virus serotypes 1–4 in the replicative background of the attenuated dengue virus type-2 (DENV-2) PD