Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Claire Xi Zhang"'
Autor:
Yuan Guan, Xiaofang Zhao, Fengwei Liu, Shuxin Yan, Yalong Wang, Cuilian Du, Xiuyu Cui, Rena Li, Claire Xi Zhang
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Recent studies suggest that the cell-to-cell spread of pathological α-synuclein (α-syn) plays important roles in the development of Parkinson’s disease (PD). PD patients who carry α-syn gene mutations often have an earlier onset and more severe
Externí odkaz:
https://doaj.org/article/283004d737cf499f80d910e724a2b5c2
Autor:
Wei Xiong, Tao Liu, Yeshi Wang, Xiaowei Chen, Lei Sun, Ning Guo, Hui Zheng, Lianghong Zheng, Martial Ruat, Weiping Han, Claire Xi Zhang, Zhuan Zhou
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e24573 (2011)
AIM: Neurotransmitter release is elicited by an elevation of intracellular Ca(2+) concentration ([Ca(2+)](i)). The action potential triggers Ca(2+) influx through Ca(2+) channels which causes local changes of [Ca(2+)](i) for vesicle release. However,
Externí odkaz:
https://doaj.org/article/566ac8c9e37b43e1ae677a1c60d70953
Autor:
Yuan Guan, Claire Xi Zhang, Xiaofang Zhao, Shuxin Yan, Meiqin Hu, Fengwei Liu, Yuhong Li, Rena Li, Yalong Wang
Publikováno v:
Molecular Neurobiology. 59:405-419
The cell-to-cell transmission of pathological α-synuclein (α-syn) has been proposed to be a critical event in the development of synucleinopathies. Recent studies have begun to reveal the underlying molecular mechanism of α-syn propagation. As one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d49ca494e695ad46bf363cf85c20981
https://doi.org/10.1007/s12035-021-02599-0
https://doi.org/10.1007/s12035-021-02599-0
Autor:
Wan-Ru Li, Feifan Zhang, Yalong Wang, Claire Xi Zhang, Chao Li, Jing-Chen Li, Meiqin Hu, Rena Li, Pei Gao, Shuli Zhang
Publikováno v:
Journal of Neurochemistry. 159:729-741
Recent work has revealed that spontaneous release plays critical roles in the central nervous system, but how it is regulated remains elusive. Here we report that synaptotagmin-11 (Syt11), a Ca2+ -independent Syt isoform associated with schizophrenia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fab1c0fce6fa85e0e29402e3ccf130e9
https://doi.org/10.1111/jnc.15523
https://doi.org/10.1111/jnc.15523
Publikováno v:
Molecular Neurobiology. 58:2874-2885
α-Klotho is known for its aging-related functions and is associated with neurodegenerative diseases, accelerated aging, premature morbidity, and mortality. Recent literature suggests that α-Klotho is also involved in the regulation of mental functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8012046a4e18facc3b4146019dfb93ca
https://doi.org/10.1007/s12035-021-02313-0
https://doi.org/10.1007/s12035-021-02313-0
Publikováno v:
Chemical Communications. 56:5441-5444
A liquid crystal biosensor based on DNA aptamer for sensitive detection of Parkinson's Disease (PD) related alpha-synuclein was developed. This LC biosensor is constructed using a simple and label free method, and it not only enables early PD diagnos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77eb0bc3fa214a9d29ebe7848360e5d0
https://doi.org/10.1039/d0cc01025a
https://doi.org/10.1039/d0cc01025a
Autor:
Yalong Wang, Claire Xi Zhang, Xiaomin Wang, Yuan Guan, Le Wang, Xiaofang Zhao, Xiaoli Gong, Shuxin Yan, Feng Yan, Yujia Zhang, Xiuyu Cui, Pei Gao, Fengwei Liu, Cuilian Du
Publikováno v:
The FASEB Journal. 34:2609-2624
Caveolae play crucial roles in intracellular membrane trafficking and mechanosensation. In this study, we report that synaptotagmin-11 (Syt11), a synaptotagmin isoform associated with Parkinson's disease and schizophrenia, regulates both caveolae-med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db2ff476a0f1515b8ee7aef4eaeef35e
https://doi.org/10.1096/fj.201901715r
https://doi.org/10.1096/fj.201901715r
Autor:
Xiuxiu Yang, Xiaofang Zhao, Hansen Zhao, Fengwei Liu, Sichun Zhang, Claire Xi Zhang, Zhongqiang Yang
Publikováno v:
Chemistry – An Asian Journal. 17
α-Synuclein is a central player in Parkinson's disease (PD) pathology. Various point mutations in α-synuclein have been identified to alter the protein-phospholipid binding behavior and cause PD. Therefore, exploration of α-synuclein-phospholipid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7a9fdd1bd5203f6b8523995e43b94b7
https://doi.org/10.1002/asia.202101251
https://doi.org/10.1002/asia.202101251
Autor:
Xiaofang, Zhao, Yuan, Guan, Fengwei, Liu, Shuxin, Yan, Yalong, Wang, Meiqin, Hu, Yuhong, Li, Rena, Li, Claire Xi, Zhang
Publikováno v:
Molecular neurobiology. 59(1)
The cell-to-cell transmission of pathological α-synuclein (α-syn) has been proposed to be a critical event in the development of synucleinopathies. Recent studies have begun to reveal the underlying molecular mechanism of α-syn propagation. As one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f4235594f8c34e53cd2a6ff79accfb55
https://pubmed.ncbi.nlm.nih.gov/34705229
https://pubmed.ncbi.nlm.nih.gov/34705229
Autor:
Yalong Wang, Rena Li, Yuan Guan, Claire Xi Zhang, Xiuyu Cui, Xiaofang Zhao, Shuxin Yan, Fengwei Liu, Cuilian Du
Publikováno v:
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Recent studies suggest that the cell-to-cell spread of pathological α-synuclein (α-syn) plays important roles in the development of Parkinson’s disease (PD). PD patients who carry α-syn gene mutations often have an earlier onset and more severe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c2b9c441a96fe2f52dd3f53a41f4d8
http://europepmc.org/articles/PMC7303300
http://europepmc.org/articles/PMC7303300