Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Claire Weatherburn"'
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Comparison of intermittent and continuous extracorporeal treatments for the enhanced elimination of dabigatran
Autor: Josette Eris, Claire Weatherburn, Huyen Tran, Geoffrey Kershaw, David Williamson, Amélie Bernier-Jean, Josée Bouchard, Marc Ghannoum, Jignesh P. Patel, Darren M. Roberts
Publikováno v: Clinical Toxicology. 53:156-163
Severe bleeding associated with dabigatran frequently requires intensive care management. An antidote is currently unavailable and data reporting the effect of dialysis on elimination of dabigatran are encouraging, but limited. Objective. To report t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de051f06cd76f0789e98197847038af
https://doi.org/10.3109/15563650.2015.1004580
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3
Multiple myeloma causes clonal T-cell immunosenescence: identification of potential novel targets for promoting tumour immunity and implications for checkpoint blockade
Autor: John Gibson, Narelle Woodland, Phoebe Joy Ho, S Yang, Derek N.J. Hart, Najah T. Nassif, Ross Brown, Claire Weatherburn, Christian E Bryant, Pasquale M Barbaro, Hayley Suen, Douglas E. Joshua
Publikováno v: Leukemia. 30(8)
Tumour-induced dysfunction of cytotoxic T cells in patients with multiple myeloma (MM) may contribute to immune escape and be responsible for the lack of therapeutic efficacy of immune checkpoint blockade. We therefore investigated dysfunctional clon
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e2c44aedd0f571acf97a3f7f7df836
https://pubmed.ncbi.nlm.nih.gov/27102208
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4
Digital PCR for MRD detection of myeloma
Autor: Najah T. Nassif, Narelle Woodland, Derek N.J. Hart, S Yang, Simon McAuliffe, Phoebe Joy Ho, D. E. Joshua, Ross Brown, Cheryl L. Paul, John Gibson, Claire Weatherburn, Alberto Catalano, Hayley Suen
A pilot study was performed to investigate the use of digital PCR (dPCR) to detect minimal residual disease (MRD) in patients with multiple myeloma. dPCR allows greater quantitative specificity in PCR reactions by performing multiple, minute PCR reac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ba8d827522b061dab24a00c0866630
https://hdl.handle.net/10453/37600
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6
Myeloid derived suppressor cells are numerically, functionally and phenotypically different in patients with multiple myeloma
Autor: Najah T. Nassif, John Gibson, Tulita Liyadipitiya, Shihong Yang, Phillip D. Fromm, James Favaloro, Claire Weatherburn, Hayley Suen, Ross Brown, Douglas E. Joshua, P. Joy Ho, Derek N.J. Hart, Narelle Woodland
Publikováno v: Leukemialymphoma. 55(12)
© 2014 Informa UK, Ltd. Myeloid derived suppressor cells (MDSCs) are a heterogeneous population of cells that have been implicated as inhibitors of lymphopoiesis in patients with malignancies. They have a consensus phenotype of CD33+/CD11b+/HLA-DRlo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b6a22f7eb065eefbd5090d21f9c97a
https://pubmed.ncbi.nlm.nih.gov/24716461
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7
Phospho-flow detection of constitutive and cytokine-induced pSTAT3/5, pAKT and pERK expression highlights novel prognostic biomarkers for patients with multiple myeloma
Autor: Claire Weatherburn, S Yang, Phoebe Joy Ho, Ross Brown, John Gibson, Hayley Suen, Derek N.J. Hart, Douglas E. Joshua
Publikováno v: Leukemia. 29(2)
Identifying check points in cell signal transduction pathways has led to the development of new cancer therapies; however, relatively few studies have determined the diagnostic and prognostic significance of analysing phosphorylated signaling protein
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbc86feaea8e3397be0b38ede3c7e910
https://pubmed.ncbi.nlm.nih.gov/24990616
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8
A Blood Dendritic Cell Vaccine for Acute Myeloid Leukemia
Autor: Shihong Yang, Phillip D. Fromm, Michael S. Papadimitrious, Phoebe Joy Ho, Christian E Bryant, John Gibson, Claire Weatherburn, Derek N.J. Hart, Harry J. Iland, Douglas E. Joshua, Hayley Suen, Robin Gasiorowski, Georgina J. Clark, Jennifer Hsu, Daniel Orellana, Ross D. Brown
Publikováno v: Blood. 128:5221-5221
Many acute myeloid leukemia (AML) patients achieve a complete remission (CR) with chemotherapy but relapse is common. Removal of residual disease remains the greatest challenge. Allogeneic transplantation (alloHCT) addresses this through an immune-me
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d3a9bc612ac1044c96cde05a222446a
https://doi.org/10.1182/blood.v128.22.5221.5221
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9
Phospho-Flow Cytometry Quantitation of STAT Signalling Checkpoints in Malignant and Non-Malignant Cells Identifies Patients Suitable for pSTAT3 and 5 Targeted Inhibitors
Autor: Christian E Bryant, Derek N.J. Hart, Ross D. Brown, Shihong Yang, Claire Weatherburn, Douglas E. Joshua, P. Joy Ho, John Gibson, Stephen Larsen, Hayley Suen
Publikováno v: Blood. 126:5356-5356
Background IL-6 receptor/JAK/STAT is a major signalling pathway associated with pleiotropic functions including cell transformation and proliferation. STAT3, one of a family of 7 STAT members, sits at the apex of the signalling cascade and is a poten
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::17926a57cb0e43123a15cdaa0809fa6e
https://doi.org/10.1182/blood.v126.23.5356.5356
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