Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Claire W, Chen"'
Autor:
Maria I. Avrutsky, Claire W. Chen, Jacqueline M. Lawson, Scott J. Snipas, Guy S. Salvesen, Carol M. Troy
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
PurposeRetinal vein occlusion (RVO) is a sight-threatening condition typically treated with intravitreal injection of vascular endothelial growth factor (VEGF) antagonists. Treatment response to anti-VEGF therapies is highly variable, with poor visua
Externí odkaz:
https://doaj.org/article/343ce8dd0fbf4bde92bc9cbfe8a8de51
Autor:
Maria I. Avrutsky, Crystal Colón Ortiz, Kendra V. Johnson, Anna M. Potenski, Claire W. Chen, Jacqueline M. Lawson, Alexandra J. White, Stephanie K. Yuen, Fatima N. Morales, Elisa Canepa, Scott Snipas, Guy S. Salvesen, Ying Y. Jean, Carol M. Troy
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Retinal vein occlusion can cause blindness, and features neuronal dysfunction, inflammation and breakdown of vascular integrity. Here the authors report a non-apoptotic role of endothelial caspase-9 in regulating blood-retina barrier integrity and ne
Externí odkaz:
https://doaj.org/article/4688da8d4e524bccb33f889dc5ad0823
Autor:
Maria I. Avrutsky, Crystal Colón Ortiz, Kendra V. Johnson, Anna M. Potenski, Claire W. Chen, Jacqueline M. Lawson, Alexandra J. White, Stephanie K. Yuen, Fatima N. Morales, Elisa Canepa, Scott Snipas, Guy S. Salvesen, Ying Y. Jean, Carol M. Troy
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/3967406557774ccfbdefb75fc3e62a7e
Publikováno v:
Translational vision sciencetechnology. 11(8)
To characterize postnatal ocular pathology in a Ndufs4-/- mouse model of complex I deficiency using noninvasive retinal imaging and visual testing.Ndufs4-/- mice and wild-type (WT) littermates were analyzed at 3, 5, and 7 weeks postnatal. Retinal mor
Autor:
Carol M. Troy, Maria I. Avrutsky, Ying Y. Jean, Scott J. Snipas, Claire W. Chen, Kendra V. Johnson, Anna M. Potenski, Crystal K. Colón Ortiz
Publikováno v:
J Vis Exp
The family of caspases is known to mediate many cellular pathways beyond cell death, including cell differentiation, axonal pathfinding, and proliferation. Since the identification of the family of cell death proteases, there has been a search for to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c5127d97b259b0b98ae2e3abe3e231d
https://europepmc.org/articles/PMC9499738/
https://europepmc.org/articles/PMC9499738/
Publikováno v:
J Vis Exp
Advancements in ophthalmic imaging tools offer an unprecedented level of access to researchers working with animal models of neurovascular injury. To properly leverage this greater translatability, there is a need to devise reproducible methods of dr
Publikováno v:
Journal of Visualized Experiments.
Autor:
Claire W. Chen, Maria Avrutsky, Jacqueline Lawson, Stephanie K. Yuen, Anna Michelle Potenski, Ying Y. Jean, Fatima N. Morales, Kendra V. Johnson, Crystal Koralis Colón Ortiz, Scott J. Snipas, Carol M. Troy, Guy S. Salvesen, Alexandra J. White, Elisa Canepa
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications
Nature Communications
Central nervous system ischemic injury features neuronal dysfunction, inflammation and breakdown of vascular integrity. Here we show that activation of endothelial caspase-9 after hypoxia-ischemia is a critical event in subsequent dysfunction of the
Autor:
Kendra V. Johnson, Crystal Koralis Colón Ortiz, Carol M. Troy, Claire W. Chen, Ying Y. Jean, Stephanie K. Yuen, Maria Avrutsky, Jacqueline Lawson, Elisa Canepa, Alexandra J. White, Anna Michelle Potenski, Fatima N. Morales, Guy S. Salvesen, Scott J. Snipas
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
Central nervous system ischemic injury features neuronal dysfunction, inflammation and breakdown of vascular integrity. Here we show that activation of endothelial caspase-9 after hypoxia-ischemia is a critical event in subsequent dysfunction of the