Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Claire Vivo"'
Autor:
Ki-Up Kim, Abigail E. Hunt, Keith S. Abayasiriwardana, Kevin K. Lee, Dario Barbone, V. Courtney Broaddus, Gerard I. Evan, Tobias B. Dansen, Claire Vivo
Publikováno v:
Molecular Cancer Therapeutics. 6:2766-2776
Tumor necrosis factor–related apoptosis inducing ligand (TRAIL) holds promise for the treatment of tumors; however, many tumors are resistant to TRAIL alone. We previously showed that resistant malignant mesothelioma cells are sensitized to TRAIL-i
Autor:
Brian Davis, Mikhail V. Blagosklonny, Igor B. Roninson, Zoya N. Demidenko, Eugenia V. Broude, Mari E. Swift, Claire Vivo
Publikováno v:
Cell Cycle. 6:1467-1470
Cell cycle arrest in response to DNA damage involves protein stabilization and consequent upregulation of p53, which induces transcription of cyclin-dependent kinase inhibitor p21 (CDKN1A). We now show that p21 acts as a negative regulator of the cel
Publikováno v:
Cancer Genetics and Cytogenetics. 152:42-51
Interferon-gamma (IFN-gamma) has been found to be antiproliferative and antitumoral in malignant mesothelioma (MM), but the MM cell response to IFN-gamma has not been fully characterized so far. We investigated gene expression profiles in human MM ce
Cell cycle checkpoint status in human malignant mesothelioma cell lines: response to gamma radiation
Autor:
F Levy, P Piedbois, Claire Vivo, Y Kirova, Karen Leroy, M C Jaurand, C Lecomte, Dominique Chopin, Laurence Kheuang, Annie Renier
Publikováno v:
British Journal of Cancer
Knowledge of the function of the cell cycle checkpoints in tumour cells may be important to develop treatment strategies for human cancers. The protein p53 is an important factor that regulates cell cycle progression and apoptosis in response to drug
Autor:
Jocelyne Fleury-Feith, I Monnet, F Levy, P Chretien, Y. Pilatte, Claire Vivo, Laurence Kheuang, M C Jaurand
Publikováno v:
Oncogene. 20:1085-1093
Recombinant human interferon gamma (r-hu-IFNgamma) exerts both antitumoral activity in the early stages of human malignant mesothelioma and a cytostatic effect in human mesothelioma (HM) cell lines in vitro. The antiproliferative effect of interferon
Autor:
Sylviane Moritz, Yannick Pilatte, Jocelyne Fleury-Feith, Annie Renier, Claire Vivo, V Levresse, Françoise Levy, Marie-Claude Jaurand
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 17:660-671
The control of DNA integrity in mammalian cells is important to maintain the cell homeostasis and prevent neoplastic transformation. Control of cell division and cell death permits repair or elimination of damaged cells. Since asbestos fibers can pro
Autor:
Eugenia V, Broude, Zoya N, Demidenko, Claire, Vivo, Mari E, Swift, Brian M, Davis, Mikhail V, Blagosklonny, Igor B, Roninson
Publikováno v:
Cell cycle (Georgetown, Tex.). 6(12)
Cell cycle arrest in response to DNA damage involves protein stabilization and consequent upregulation of p53, which induces transcription of cyclin-dependent kinase inhibitor p21 (CDKN1A). We now show that p21 acts as a negative regulator of the cel
Autor:
Eugenia V. Broude, Mikhail V. Blagosklonny, Bey-Dih Chang, Brian Davis, S Kalurupalle, Igor B. Roninson, Swift Me, Claire Vivo
Publikováno v:
Oncogene. 26(48)
Damage-induced G1 checkpoint in mammalian cells involves upregulation of p53, which activates transcription of p21(Waf1) (CDKN1A). Inhibition of cyclin-dependent kinase (CDK)2 and CDK4/6 by p21 leads to dephosphorylation and activation of Rb. We now
Publikováno v:
The Journal of biological chemistry. 278(28)
Apoptotic resistance of cancer cells may be overcome by the combination of treatments that activate the two major apoptotic pathways: (i) the death receptor pathway activated by death ligands and (ii) the DNA damage pathway activated by chemotherapy.
Autor:
Annie Renier, Laurence Kheuang, Marie-Claude Jaurand, Claire Vivo, Anne Greffard, Yannick Pilatte
Publikováno v:
American journal of respiratory cell and molecular biology. 23(6)
Simian virus (SV) 40 and SV40-like DNA sequences have recently been detected in several types of human tumors, including malignant mesothelioma. However, the presence of SV40 DNA sequences is not sufficient to account for its possible role in tumor d