Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Claire Soave"'
Autor:
Claire Soave, Charles Ducker, Naeyma Islam, Seongho Kim, Sally Yurgelevic, Nathan I. Nicely, Luke Pardy, Yanfang Huang, Peter E. Shaw, Gregory Auner, Alex Dickson, Manohar Ratnam
Publikováno v:
Molecular Pharmacology. 103:211-220
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac00f614771eba82c67081e9038e9844
https://doi.org/10.1124/molpharm.122.000589
https://doi.org/10.1124/molpharm.122.000589
Publikováno v:
Prostate
Background Both hormone-sensitive and castration- and enzalutamide-resistant prostate cancers (PCa) depend on the ternary complex factor (TCF) protein ELK1 to serve as a tethering protein for the androgen receptor (AR) to activate a critical set of g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc75bb43a0c42c0e5c400a2ebe9ace3
https://doi.org/10.1002/pros.23932
https://doi.org/10.1002/pros.23932
Publikováno v:
Cancer Research. 81:2469-2469
Prostate cancer (PC) is generally dependent on the androgen signaling axis for growth. Advanced PC is managed by androgen deprivation therapy (ADT). However, the tumors frequently progress by restoring AR signaling that is androgen-independent or hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37f1d30f351e260f393f0b3318e9aea9
https://doi.org/10.1158/1538-7445.am2021-2469
https://doi.org/10.1158/1538-7445.am2021-2469
Publikováno v:
Cancer and Metastasis Reviews. 36:717-736
In the past fifteen years, the proteasome has been validated as an anticancer drug target and 20S proteasome inhibitors (such as bortezomib and carfilzomib) have been approved by the FDA for the treatment of multiple myeloma and some other liquid tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab74c95197f365b23ffaa5607bb7cb46
https://doi.org/10.1007/s10555-017-9705-x
https://doi.org/10.1007/s10555-017-9705-x
Autor:
Kush Patel, Robert Foldes, Tracey Guerin Edbauer, Reda Saber Ibrahim Ahmed, Antonio Vinicius Pazetti de Oliveira, Tak Hang Chan, Yasmine Elghoul, Andrea Renzetti, Q. Ping Dou, Claire Soave
Publikováno v:
Medicinal Plants ISBN: 9783030312688
Green tea polyphenols, especially catechins, have shown great promise for use as anticancer agents. One such catechin, epigallocatechin-3 gallate (EGCG), is of particular interest due to mounting evidence of its ability to interrupt a variety of esse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17b43058846db35b818734473504973e
https://doi.org/10.1007/978-3-030-31269-5_14
https://doi.org/10.1007/978-3-030-31269-5_14
Autor:
Reda Saber Ibrahim Ahmed, Claire Soave, Gang Liu, Huanjie Yang, Pershang Farshi, Ashraf A. El-Ghoneimy, Robert Foldes, Tak Hang Chan, Q. Ping Dou, H. A. El-Banna, Andrea Renzetti, Ghassan M. Saed
Publikováno v:
Journal of Cellular Biochemistry. 117:2357-2369
Uterine fibroids (leiomyomas) are very common benign tumors grown on the smooth muscle layer of the uterus, present in up to 75% of reproductive-age women and causing significant morbidity in a subset of this population. Although the etiology and bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebce160fd76822f50a1578e230318a8f
https://doi.org/10.1002/jcb.25533
https://doi.org/10.1002/jcb.25533
Autor:
Stephanie Lucas, Ghazal Nabil, Guohua Chen, Q. Ping Dou, Jian Wang, H. A. El-Banna, Claire Soave, Zainab Sabry Othman Ahmed
Publikováno v:
Recent Patents on Anti-Cancer Drug Discovery. 12
Background: Alteration of cellular metabolism is a hallmark of cancer, which underlies exciting opportunities to develop effective, anti-cancer therapeutics by targeting through inhibition of cancer metabolism. Nicotinamide adenine dinucleotide (NAD+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::992ad3c90be1d5688346433443c312c1
https://doi.org/10.2174/1574892812666170619125503
https://doi.org/10.2174/1574892812666170619125503
Autor:
Reda Saber Ibrahim, Ahmed, Gang, Liu, Andrea, Renzetti, Pershang, Farshi, Huanjie, Yang, Claire, Soave, Ghassan, Saed, Ashraf Ahmed, El-Ghoneimy, Hossny Awad, El-Banna, Robert, Foldes, Tak-Hang, Chan, Q Ping, Dou
Publikováno v:
Journal of cellular biochemistry. 117(10)
Uterine fibroids (leiomyomas) are very common benign tumors grown on the smooth muscle layer of the uterus, present in up to 75% of reproductive-age women and causing significant morbidity in a subset of this population. Although the etiology and bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc3bf1824194af41ddeba445f871ffc2
https://pubmed.ncbi.nlm.nih.gov/26950525
https://pubmed.ncbi.nlm.nih.gov/26950525
Publikováno v:
Journal of Developing Drugs.
Disulfiram (tetra ethyl thiuram disulfide, or DSF), is a disulfide derivative of N, N-diethyl dithiocarbamate (DEDTC). DSF is an FDA approved drug for the treatment of alcoholism, and at low doses continues to be a useful treatment option for those s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2785eaf0016ca8161c6a3f9e02e9f674
https://doi.org/10.4172/2329-6631.1000e147
https://doi.org/10.4172/2329-6631.1000e147
Autor:
J.-L. Bosson, Claire Soave, Yoann Gaboreau, Elena Chidlovskii, Pascal Couturier, Audrey Lebelhomme, Gilles Pernod
Publikováno v:
Geriatrie et psychologie neuropsychiatrie du vieillissement. 13(3)
Bleeding is the main complication on vitamin K antagonist treatment (VKA), particularly in elderly patients. However, the bleeding risk prediction in geriatric patients remains difficult. We evaluated the predictive value of the HAS-BLED and ATRIA bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55db1752c5c39f756414deffa825d958
https://pubmed.ncbi.nlm.nih.gov/26395301
https://pubmed.ncbi.nlm.nih.gov/26395301