Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Claire Snowdon"'
Autor:
Annabelle South, Claire Snowdon, Eva Burnett, Barbara E. Bierer, Katie Gillies, Talia Isaacs, Matthew R. Sydes
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-18 (2024)
Abstract Background Sharing trial results with participants is a moral imperative, but too often does not happen in appropriate ways. Methods We carried out semi-structured interviews with patients (n = 13) and site staff (n = 11), and surveyed 180 p
Externí odkaz:
https://doaj.org/article/4821c719f2054037b6d8620aa4304957
Autor:
Graeme Maclennan, Nick Heywood, Clare Clement, Natalie S Blencowe, Jane Blazeby, Dmitri Nepogodiev, Laura Magill, Alejandro Arenas-Pinto, Tom Pinkney, J Athene Lane, James Glasbey, Victoria Hardy, Karen Coulman, Jonathan Alistair Cook, Claire Snowdon, Richard Bulbulia, Zoe Hilton
Publikováno v:
BMJ Open, Vol 13, Iss 12 (2023)
Objectives This study aimed to understand the role of surgical Trainee Research Collaboratives (TRCs) in conducting randomised controlled trials and identify strategies to enhance trainee engagement in trials.Design This is a mixed methods study. We
Externí odkaz:
https://doaj.org/article/d375cf02f903440b8a5cd72a82ac7b77
Autor:
Claire Snowdon, Elizabeth Silver, Paul Charlton, Brian Devlin, Emma Greenwood, Andrew Hutchings, Susan Moug, Ravinder Vohra, Richard Grieve
Publikováno v:
Health Expectations, Vol 26, Iss 4, Pp 1658-1667 (2023)
Abstract Background The COVID‐19 pandemic brought rapid and major changes to research, and those wishing to carry out Patient and Public Involvement (PPI) activities faced challenges, such as restrictions on movement and contact, illness, bereaveme
Externí odkaz:
https://doaj.org/article/a9e9c73a7e7745c88553b81cf886e254
Autor:
Sharon B. Love, Fay Cafferty, Claire Snowdon, Karen Carty, Joshua Savage, Philip Pallmann, Lucy McParland, Louise Brown, Lindsey Masters, Francesca Schiavone, Dominic Hague, Stephen Townsend, Claire Amos, Annabelle South, Kate Sturgeon, Ruth Langley, Timothy Maughan, Nicholas James, Emma Hall, Sarah Kernaghan, Judith Bliss, Nick Turner, Andrew Tutt, Christina Yap, Charlotte Firth, Anthony Kong, Hisham Mehanna, Colin Watts, Robert Hills, Ian Thomas, Mhairi Copland, Sue Bell, David Sebag-Montefiore, Robert Jones, Mahesh K. B. Parmar, Matthew R. Sydes
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-14 (2022)
Abstract Background Late-phase platform protocols (including basket, umbrella, multi-arm multi-stage (MAMS), and master protocols) are generally agreed to be more efficient than traditional two-arm clinical trial designs but are not extensively used.
Externí odkaz:
https://doaj.org/article/f16f51eff76c45b9b2545597e35df8a3
Autor:
James M. S. Wason, Munyaradzi Dimairo, Katie Biggs, Sarah Bowden, Julia Brown, Laura Flight, Jamie Hall, Thomas Jaki, Rachel Lowe, Philip Pallmann, Mark A. Pilling, Claire Snowdon, Matthew R. Sydes, Sofía S. Villar, Christopher J. Weir, Nina Wilson, Christina Yap, Helen Hancock, Rebecca Maier
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Adaptive designs are a class of methods for improving efficiency and patient benefit of clinical trials. Although their use has increased in recent years, research suggests they are not used in many situations where they have potential to br
Externí odkaz:
https://doaj.org/article/22339b16e2cc4f4288ebaef1419f4518
Autor:
Claire Snowdon, Sarah Kernaghan, Laura Moretti, Nicholas C. Turner, Alistair Ring, Katie Wilkinson, Sue Martin, Stephanie Foster, Lucy S. Kilburn, Judith M. Bliss
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-10 (2022)
Abstract Background Platform trial designs are used increasingly in cancer clinical research and are considered an efficient model for evaluating multiple compounds within a single disease or disease subtype. However, these trial designs can be chall
Externí odkaz:
https://doaj.org/article/95aec4e90bb041c8a063405e0216014f
Autor:
Richard Grieve, Andrew Hutchings, Silvia Moler Zapata, Stephen O’Neill, David G Lugo-Palacios, Richard Silverwood, David Cromwell, Tommaso Kircheis, Elizabeth Silver, Claire Snowdon, Paul Charlton, Geoff Bellingan, Ramani Moonesinghe, Luke Keele, Neil Smart, Robert Hinchliffe
Publikováno v:
Health and Social Care Delivery Research, Vol 11, Iss 1 (2023)
Background: Evidence is required on the clinical effectiveness and cost-effectiveness of emergency surgery compared with non-emergency surgery strategies (including medical management, non-surgical procedures and elective surgery) for patients admitt
Externí odkaz:
https://doaj.org/article/273bb18081dc4ea8ae13c1f9dbd2f462
Autor:
Nina Wilson, Katie Biggs, Sarah Bowden, Julia Brown, Munyaradzi Dimairo, Laura Flight, Jamie Hall, Anna Hockaday, Thomas Jaki, Rachel Lowe, Caroline Murphy, Philip Pallmann, Mark A. Pilling, Claire Snowdon, Matthew R. Sydes, Sofía S. Villar, Christopher J. Weir, Jessica Welburn, Christina Yap, Rebecca Maier, Helen Hancock, James M. S. Wason
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-17 (2021)
Abstract Background Adaptive designs offer great promise in improving the efficiency and patient-benefit of clinical trials. An important barrier to further increased use is a lack of understanding about which additional resources are required to con
Externí odkaz:
https://doaj.org/article/54a6d8a22728449aaca970ea965fdb82
Autor:
Zahra Jamal, Alexander Perkins, Christopher Allen, Research Advisory Group, Richard Evans, Joanna Sturgess, Claire Snowdon, Tim Clayton, Diana Elbourne
Publikováno v:
Research Involvement and Engagement, Vol 7, Iss 1, Pp 1-7 (2021)
Plain English summary Patient and Public Involvement (PPI) describes the active involvement of patients and the public in the research process. Through PPI, patients and members of the public are increasingly involved in the design and conduct of cli
Externí odkaz:
https://doaj.org/article/02bbd689d0614dbfb92b7f41784dbefe
Autor:
Clair Le Boutillier, Claire Snowdon, Vishal Patel, Mark McPhail, Christopher Ward, Ben Carter, Ruhama Uddin, Ane Zamalloa, Vanessa Lawrence
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0263288 (2022)
ObjectiveThe success of pharmacological randomised controlled trials (RCTs) depends on the recruitment of the required number of participants. Recruitment to RCTs for patients with cirrhosis and small oesophageal varices raises specific additional ch
Externí odkaz:
https://doaj.org/article/0ce7f22b7cf94779918538579070b67e