Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Claire Smalley Rumfield"'
Autor:
Samuel T. Pellom, Claire Smalley Rumfield, Y. Maurice Morillon II, Nicholas Roller, Lisa K. Poppe, Douglas E. Brough, Helen Sabzevari, Jeffrey Schlom, Caroline Jochems
Publikováno v:
JCI Insight, Vol 6, Iss 7 (2021)
There are approximately 44,000 cases of human papillomavirus–associated (HPV-associated) cancer each year in the United States, most commonly caused by HPV types 16 and 18. Prophylactic vaccines successfully prevent healthy people from acquiring HP
Externí odkaz:
https://doaj.org/article/23d2fa7a4ec74f2a9d94ecf908385524
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background While prophylactic human papillomavirus (HPV) vaccines will certainly reduce the incidence of HPV-associated cancers, these malignancies remain a major health issue. PDS0101 is a liposomal-based HPV therapeutic vaccine consisting of the im
Externí odkaz:
https://doaj.org/article/499f17fbdd6d46d39861faa21701564c
Autor:
Y. Maurice Morillon, Claire Smalley Rumfield, Samuel T. Pellom, Ariana Sabzevari, Nicholas T. Roller, Lucas A. Horn, Caroline Jochems, Claudia Palena, John W. Greiner, Jeffrey Schlom
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The lack of serial biopsies in patients with a range of carcinomas has been one obstacle in our understanding of the mechanism of action of immuno-oncology agents as well as the elucidation of mechanisms of resistance to these novel therapeutics. Whi
Externí odkaz:
https://doaj.org/article/17c83c0e943345a1970124ea7637a98b
Autor:
Caroline Jochems, Sarah R. Tritsch, Karin M. Knudson, Sofia R. Gameiro, Claire Smalley Rumfield, Samuel T. Pellom, Y. Maurice Morillon, Robby Newman, Warren Marcus, Christopher Szeto, Shahrooz Rabizadeh, Hing C. Wong, Patrick Soon-Shiong, Jeffrey Schlom
Publikováno v:
OncoImmunology, Vol 8, Iss 2 (2019)
Here we describe a novel bifunctional fusion protein, designated N-809. This molecule comprises the IL-15/IL15Rα superagonist complex containing the Fc-domain of IgG1 (N-803, formerly designated as ALT-803) fused to two single chain anti-PD-L1 domai
Externí odkaz:
https://doaj.org/article/44c44230f6754047981633a4bd819a06
Autor:
Helen Sabzevari, Jeffrey Schlom, Nicholas Roller, Samuel T. Pellom, Claire Smalley Rumfield, Douglas E. Brough, Caroline Jochems, Lisa K. Poppe, Y. Maurice Morillon
Publikováno v:
JCI Insight
JCI Insight, Vol 6, Iss 7 (2021)
JCI Insight, Vol 6, Iss 7 (2021)
There are approximately 44,000 cases of human papillomavirus–associated (HPV-associated) cancer each year in the United States, most commonly caused by HPV types 16 and 18. Prophylactic vaccines successfully prevent healthy people from acquiring HP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112338e58ea596f70b12e172e6c75e0d
https://doi.org/10.1172/jci.insight.141912
https://doi.org/10.1172/jci.insight.141912
Autor:
Caroline Jochems, Nicole Toney, Claire Smalley Rumfield, James L. Gulley, Renee N. Donahue, Samuel T. Pellom, Yo-Ting Tsai, Jeffrey Schlom, Julius Strauss
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background The safety and efficacy of bintrafusp alfa, a first-in-class bifunctional fusion protein composed of the extracellular domain of the TGF-βRII receptor (a TGF-β ‘trap’) fused to a human IgG1 mAb blocking PD-L1, have been demonstrated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac3e08550dcdf24556836aba1b8f46f7
https://doaj.org/article/56a5f63dd8094d879f8beceba53f2ae1
https://doaj.org/article/56a5f63dd8094d879f8beceba53f2ae1
Autor:
Ariana Sabzevari, Claire Smalley Rumfield, Nicholas Roller, Claudia Palena, John W. Greiner, Y. Maurice Morillon, Caroline Jochems, Samuel T Pellom, Jeffrey Schlom, Lucas A. Horn
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 10 (2020)
Frontiers in Oncology, Vol 10 (2020)
The lack of serial biopsies in patients with a range of carcinomas has been one obstacle in our understanding of the mechanism of action of immuno-oncology agents as well as the elucidation of mechanisms of resistance to these novel therapeutics. Whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beea5e6cf4faa25c5ac7e7ca02103621
https://doi.org/10.3389/fonc.2020.00549
https://doi.org/10.3389/fonc.2020.00549
Publikováno v:
Infect Immun
Rickettsiae are cytosolically replicating, obligately intracellular bacteria causing human infections worldwide with potentially fatal outcomes. We previously showed that Rickettsia australis activates ASC inflammasome in macrophages. In the present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fefb801c51251b74d0afadcfc62df1d4
https://doi.org/10.1128/iai.00886-19
https://doi.org/10.1128/iai.00886-19
Autor:
Samuel Troy Pellom, Claire Smalley Rumfield, Yves Maurice Morillon, Nicholas Roller, Douglas Brough, Helen Sabzevari, Jack Greiner, Jeffrey Schlom, Caroline Jochems
Publikováno v:
The Journal of Immunology. 204:91.6-91.6
There are about 44,000 cases of Human Papilloma Virus (HPV) associated cancer each year in the US, most commonly caused by HPV 16 and 18. Prophylactic vaccines have been successful at preventing healthy patients from acquiring HPV infections via the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd67fa954bf8127d735e241b01689599
https://doi.org/10.4049/jimmunol.204.supp.91.6
https://doi.org/10.4049/jimmunol.204.supp.91.6
Autor:
Robby Newman, Jeffrey Schlom, Sofia R. Gameiro, Claire Smalley Rumfield, Y. Maurice Morillon, Hing C. Wong, Karin M. Knudson, Patrick Soon-Shiong, Christopher Szeto, Samuel T Pellom, Shahrooz Rabizadeh, Warren D. Marcus, Sarah R. Tritsch, Caroline Jochems
Publikováno v:
OncoImmunology, Vol 8, Iss 2 (2019)
Oncoimmunology
Oncoimmunology
Here we describe a novel bifunctional fusion protein, designated N-809. This molecule comprises the IL-15/IL15Rα superagonist complex containing the Fc-domain of IgG1 (N-803, formerly designated as ALT-803) fused to two single chain anti-PD-L1 domai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7466f9acdd413adbba575cd4c1cfa982
https://pubmed.ncbi.nlm.nih.gov/30713787
https://pubmed.ncbi.nlm.nih.gov/30713787