Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Claire S. Lynch"'
Publikováno v:
Biochemistry. 31:1757-1767
Mutagenesis of the dimer- and hexamer-forming surfaces of insulin yields analogues with reduced tendencies to aggregate and dramatically altered pharmacokinetic properties. We recently showed that one such analogue, HisB10----Asp, ProB28----Lys, LysB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65498236dbc4ecd51ccfea855dc154a1
https://doi.org/10.1021/bi00121a025
https://doi.org/10.1021/bi00121a025
Publikováno v:
Biochemistry. 30:7373-7389
Insulin provides an important model for the application of genetic engineering to rational protein design and has been well characterized in the crystal state. However, self-association of insulin in solution has precluded complementary 2D NMR study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80c1f1ba9d1cc9655acab3a30cc1c136
https://doi.org/10.1021/bi00244a004
https://doi.org/10.1021/bi00244a004
Publikováno v:
Peptides ISBN: 9789401050050
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d5d2ee5dbedb616c23a2d50f1f9def6
https://doi.org/10.1007/978-94-011-2264-1_16
https://doi.org/10.1007/978-94-011-2264-1_16
Publikováno v:
Peptides ISBN: 9789401050050
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdcdaf945629025487e1519b34c2d6d8
https://doi.org/10.1007/978-94-011-2264-1_17
https://doi.org/10.1007/978-94-011-2264-1_17
Autor:
Michael A. Weiss, Qing-Xin Hua, Michel Kochoyan, Claire S. Lynch, Bruce H. Frank, Steven E. Shoelson
Publikováno v:
Peptides ISBN: 9789401050050
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b0e544eb35ebc0454f030fde3ccb739
https://doi.org/10.1007/978-94-011-2264-1_6
https://doi.org/10.1007/978-94-011-2264-1_6