Neonatal Hepatic Myeloid Progenitors Expand and Propagate Liver Injury in Mice

Autor: Anas Alkhani, Cathrine Korsholm, Claire S. Levy, Sarah Mohamedaly, Caroline C. Duwaerts, Eric M. Pietras, Amar Nijagal

Publikováno v: Journal of clinical medicine, vol 12, iss 1
Journal of Clinical Medicine; Volume 12; Issue 1; Pages: 337

Background: Biliary atresia (BA) is a progressive pediatric inflammatory disease of the liver that leads to cirrhosis and necessitates liver transplantation. The rapid progression from liver injury to liver failure in children with BA suggests that f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788c446ad7dcebdd04098b725c2150fe
https://pubmed.ncbi.nlm.nih.gov/36615137

Ly6cLo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation

Autor: Aras N. Mattis, Katya Polovina, Amar Nijagal, Jacquelyn J. Maher, Claire S. Levy, Margaret Tsui, Anas Alkhani, Steven J. Van Dyken, Katherine A. Rosenberg, Matthias Mack, Bruce Wang

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific reports, vol 10, iss 1

Perinatal hepatic inflammation can have devastating consequences. Monocytes play an important role in the initiation and resolution of inflammation, and their diverse functions can be attributed to specific cellular subsets: pro-inflammatory or class

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec552d129afdf6cc1b11daea78e080c
http://link.springer.com/article/10.1038/s41598-020-64158-2

Expression of ovine herpesvirus -2 encoded microRNAs in an immortalised bovine - cell line.

Autor: Katie Nightingale, Claire S Levy, John Hopkins, Finn Grey, Suzanne Esper, Robert G Dalziel

Publikováno v: PLoS ONE, Vol 9, Iss 5, p e97765 (2014)

Ovine herpesvirus-2 (OvHV-2) infects most sheep, where it establishes an asymptomatic, latent infection. Infection of susceptible hosts e.g. cattle and deer results in malignant catarrhal fever, a fatal lymphoproliferative disease characterised by un

Externí odkaz: https://doaj.org/article/9f3c8d393b0c4d4a93ede007f21751ae

Nr4a1 As a Regulator of Monocyte Subsets in a Mouse Model of Biliary Atresia

Autor: Amar Nijagal, Claire S. Levy, Sarah Mohamedaly

Publikováno v: Journal of the American College of Surgeons. 233:S180

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::97158ee740a4e14efe06638e2a971730
https://doi.org/10.1016/j.jamcollsurg.2021.07.363

Ovine herpesvirus-2 encoded microRNAs target virus genes involved in virus latency

Autor: Aayesha Riaz, Inga Dry, Claire S. Levy, John Hopkins, Finn Grey, Darren J. Shaw, Robert G. Dalziel

Publikováno v: Riaz, A, Dry, I, Levy, C, Hopkins, J, Grey, F, Shaw, D & Dalziel, R 2014, ' Ovine herpesvirus-2 encoded microRNAs target virus genes involved in virus latency ', Journal of General Virology, vol. 95, no. 2, pp. 472-480 . https://doi.org/10.1099/vir.0.059303-0

Herpesviruses encode microRNAs (miRNAs) that target both virus and host genes; however, their role in herpesvirus biology is understood poorly. We identified previously eight miRNAs encoded by ovine herpesvirus-2 (OvHV-2), the causative agent of mali

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd4c6678404a7840da28c8793bf55abd
https://europepmc.org/articles/PMC4820034/