Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Claire Roesler"'
Autor:
Dongdong Cao, Yunrong Gao, Claire Roesler, Samantha Rice, Paul D’Cunha, Lisa Zhuang, Julia Slack, Mason Domke, Anna Antonova, Sarah Romanelli, Shayon Keating, Gabriela Forero, Puneet Juneja, Bo Liang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Respiratory syncytial virus (RSV) is a pathogenic non-segmented negative-sense RNA virus and active RSV polymerase is composed of a 250 kDa large (L) protein and tetrameric phosphoprotein (P). Here, the authors present the 3.67 Å cryo-EM structure o
Externí odkaz:
https://doaj.org/article/2acb3735a4264456be4a72bc93dc7d0d
Autor:
Taylor Rager, Adam Eckburg, Meet Patel, Rong Qiu, Shahina Gantiwala, Katrina Dovalovsky, Kelly Fan, Katie Lam, Claire Roesler, Aayush Rastogi, Shruti Gautam, Namrata Dube, Bridget Morgan, S M Nasifuzzaman, Dhruv Ramaswami, Varun Gnanasekar, Jeffrey Smith, Aftab Merchant, Neelu Puri
Publikováno v:
Cancers. 14:3779
Melanoma possesses invasive metastatic growth patterns and is one of the most aggressive types of skin cancer. In 2021, it is estimated that 7180 deaths were attributed to melanoma in the United States alone. Once melanoma metastasizes, traditional t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c44eec643891b4e0fa657d02ead0daa1
https://doi.org/10.3390/cancers14153779
https://doi.org/10.3390/cancers14153779
Autor:
Sarah Romanelli, Julia Slack, Samantha Rice, Yunrong Gao, Bo Liang, Claire Roesler, Lisa Zhuang, Anna Antonova, Dongdong Cao, Paul D’Cunha
Publikováno v:
Journal of Virology
As a major human pathogen, RSV affects 3.4 million children worldwide annually. However, no effective antivirals or vaccines are available. An in-depth mechanistic understanding of the RSV RNA synthesis machinery remains a high priority among the NNS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e71c0e17867f3859dcba4fef839d3d0c
http://europepmc.org/articles/PMC7737744
http://europepmc.org/articles/PMC7737744
Autor:
Lisa Zhuang, Bo Liang, Sarah Romanelli, Anna Antonova, Puneet Juneja, Shayon Keating, Gabriela Forero, Paul D’Cunha, Julia Slack, Claire Roesler, Dongdong Cao, Samantha Rice, Yunrong Gao, Mason Domke
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
The respiratory syncytial virus (RSV) RNA polymerase, constituted of a 250 kDa large (L) protein and tetrameric phosphoprotein (P), catalyzes three distinct enzymatic activities — nucleotide polymerization, cap addition, and cap methylation. How RS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afce42eb86e5ff6bbb5399b775262c82
https://pubmed.ncbi.nlm.nih.gov/31953395
https://pubmed.ncbi.nlm.nih.gov/31953395