Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Claire R. Weston"'
Autor:
Cristina Cellurale, Claire R Weston, Judith Reilly, David S Garlick, D Joseph Jerry, Hayla K Sluss, Roger J Davis
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12469 (2010)
The cJun NH2-terminal kinase (JNK) signal transduction pathway has been implicated in mammary carcinogenesis. To test the role of JNK, we examined the effect of ablation of the Jnk1 and Jnk2 genes in a Trp53-dependent model of breast cancer using BAL
Externí odkaz:
https://doaj.org/article/e3edcc8710984e838f206fbeb95f0e60
Autor:
Daniel E Todd, Kathryn Balmanno, Catherine Newson, Sarah A. Molton, Claire R. Weston, Simon J. Cook, Andrew Garner
Publikováno v:
Cellular Signalling. 17:1412-1422
The conditional protein kinase DeltaMEKK3:ER* allows activation of the mitogen-activated and stress-activated protein kinases (MAPKs and SAPKs) without imposing a primary cellular stress or damage. Such separation of stress from stress-induced signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7e905f852b4bb02bcd041866d98c6e5
https://doi.org/10.1016/j.cellsig.2005.02.006
https://doi.org/10.1016/j.cellsig.2005.02.006
Autor:
Anthony Wong, Richard A. Flavell, Mary E.P. Goad, Claire R. Weston, J. Perry Hall, Roger J. Davis
Publikováno v:
Proceedings of the National Academy of Sciences. 101:14114-14119
The c-Jun NH 2 -terminal kinase (JNK) group of mitogen-activated protein kinases is activated in response to a wide array of cellular stresses and proinflammatory cytokines. Roles for JNK in the developing nervous system and T-cell-mediated immunity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d260a11e45c10b520c7ab7ceecd9306
https://doi.org/10.1073/pnas.0406061101
https://doi.org/10.1073/pnas.0406061101
Autor:
Tamera Barrett, Claire R. Weston, Richard A. Flavell, Marie Helene Delmotte, Nyaya Kelkar, Roger J. Davis, Barbara J. Sheppard
Publikováno v:
Proceedings of the National Academy of Sciences. 100:9843-9848
The murine JNK-interacting protein 3 (JIP3) protein (also known as JSAP1) is expressed exclusively in neurons and has been identified as a scaffold protein for the c-Jun NH 2 -terminal kinase (JNK) signaling pathway and as an adapter protein for carg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17911983be5759e1ef8d7d69e686cbef
https://doi.org/10.1073/pnas.1733944100
https://doi.org/10.1073/pnas.1733944100
Autor:
J. Perry Hall, Richard A. Flavell, Roger J. Davis, Anthony C. Wong, Claire R. Weston, Mary E.P. Goad
Publikováno v:
Genes & Development. 17:1271-1280
The c-Jun NH2-terminal kinase (JNK) group of mitogen-activated protein kinases is stimulated in response to a wide array of cellular stresses and proinflammatory cytokines. Mice lacking individual members of theJnkfamily (Jnk1,Jnk2, andJnk3) are viab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b4ad8620adde41f1f4cb49af0cc6f2
https://doi.org/10.1101/gad.1087303
https://doi.org/10.1101/gad.1087303
Publikováno v:
Journal of Biological Chemistry. 278:18811-18816
Both the ERK and phosphatidylinositol 3'-kinase (PI3K) signaling pathways can protect cells from apoptosis following withdrawal of survival factors. We have previously shown that the ERK1/2 pathway acts independently of PI3K to block expression of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37fa0ddf701b69d9b701e3a292599120
https://doi.org/10.1074/jbc.m301010200
https://doi.org/10.1074/jbc.m301010200
Publikováno v:
Science. 296:2345-2347
Mitogen activated protein kinases (MAPKs) are components of signaling pathways that control how cells respond to their environment. There are many different MAPKs and to keep pathways distinct, particular MAPKs must bind their ligands with high speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fba30d832dc62e4856df984817935921
https://doi.org/10.1126/science.1073344
https://doi.org/10.1126/science.1073344
Autor:
Claire R. Weston, Roger J. Davis
Publikováno v:
Current opinion in cell biology. 19(2)
The c-Jun NH(2)-terminal kinase (JNK) is a member of an evolutionarily conserved sub-family of mitogen-activated protein (MAP) kinases. Recent studies have led to progress towards understanding the physiological function of the JNK signaling pathway,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47ea53de31cff0e15c26419398a0beb7
https://pubmed.ncbi.nlm.nih.gov/17303404
https://pubmed.ncbi.nlm.nih.gov/17303404
Autor:
Yasu-Taka Azuma, Richard A. Flavell, Manchuan Chen, Elise H. Tran, Claire R. Weston, Roger J. Davis
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 103(36)
Environmental insults such as microbial pathogens can contribute to the activation of autoreactive T cells, leading to inflammation of target organs and, ultimately, autoimmune disease. Various infections have been linked to multiple sclerosis and it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c383bb1c377b6afb54884048a25071
https://pubmed.ncbi.nlm.nih.gov/16938889
https://pubmed.ncbi.nlm.nih.gov/16938889
Autor:
Andrew P. Garner, Claire R. Weston, Catherine Newson, Kathryn Balmanno, Ruth M Densham, Sarah A Molton, Linda Scott, Daniel E Todd, Simon J. Cook
Publikováno v:
Oncogene. 23(19)
To study the mechanisms by which mitogen- and stress-activated protein kinases regulate cell cycle re-entry, we have used a panel of conditional kinases that stimulate defined MAPK or SAPK cascades. Activation of DeltaMEKK3:ER* during serum restimula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c7065889b43e55e35794467ab4f20e8
https://pubmed.ncbi.nlm.nih.gov/14981547
https://pubmed.ncbi.nlm.nih.gov/14981547