Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Claire R. Peghaire"'
Autor:
Neil P. Dufton, Claire R. Peghaire, Lourdes Osuna-Almagro, Claudio Raimondi, Viktoria Kalna, Abhishek Chauhan, Gwilym Webb, Youwen Yang, Graeme M. Birdsey, Patricia Lalor, Justin C. Mason, David H. Adams, Anna M. Randi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
The transcription factor ERG is key to endothelial lineage specification and vascular homeostasis. Here the authors show that ERG balances TGFβ signalling through the SMAD1 and SMAD3 pathways, protecting the endothelium from endothelial-to-mesenchym
Externí odkaz:
https://doaj.org/article/688d3e51bd6e4384bf9ccbf1181bb7d6
Autor:
Neil P. Dufton, Claire R. Peghaire, Lourdes Osuna-Almagro, Claudio Raimondi, Viktoria Kalna, Abhishek Chauhan, Gwilym Webb, Youwen Yang, Graeme M. Birdsey, Patricia Lalor, Justin C. Mason, David H. Adams, Anna M. Randi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/09a0a6c4e2f844d885132da763c799de
Autor:
Jesus M. Gomez-Salinero, Tomer Itkin, Sean Houghton, Chaitanya Badwe, Yang Lin, Viktoria Kalna, Neil Dufton, Claire R. Peghaire, Masataka Yokoyama, Matthew Wingo, Tyler M. Lu, Ge Li, Jenny Zhaoying Xiang, Yen-Michael Sheng Hsu, David Redmond, Ryan Schreiner, Graeme M. Birdsey, Anna M. Randi, Shahin Rafii
Publikováno v:
Nat Cardiovasc Res
Current dogma dictates that, during adulthood, endothelial cells (ECs) are locked in an immutable stable homeostatic state. By contrast, herein we show that maintenance of EC fate and function are linked and active processes, which depend on the cons
Autor:
Viktoria, Kalna, Youwen, Yang, Claire R, Peghaire, Karen, Frudd, Rebecca, Hannah, Aarti V, Shah, Lourdes, Osuna Almagro, Joseph J, Boyle, Berthold, Göttgens, Jorge, Ferrer, Anna M, Randi, Graeme M, Birdsey
Publikováno v:
Circulation Research
Supplemental Digital Content is available in the text.
Rationale: The ETS (E-26 transformation-specific) transcription factor ERG (ETS-related gene) is essential for endothelial homeostasis, driving expression of lineage genes and repressing pro
Rationale: The ETS (E-26 transformation-specific) transcription factor ERG (ETS-related gene) is essential for endothelial homeostasis, driving expression of lineage genes and repressing pro