Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Claire Pierra Rouviere"'
Autor:
David Dukhan, Thierry Convard, Rachid Rahali, Agnès Amador, Anna Giulia Loi, Valeria Mascia, Massimiliano LaColla, Julien Milhau, Eric Badaroux, Maria Seifer, Loredana Onidi, Ludovic Griffe, Claire Pierra Rouviere, Joe McCarville, Dominique Louis Nestor Ghislain Surleraux, Efisio Sais, Daniel Da Costa, David Standring, Jean-François Griffon, Frédéric Leroy, Michel Liuzzi, Jean-Laurent Paparin, Cyril B. Dousson
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:4536-4541
The hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase (RdRp) plays a central role in virus replication. NS5B has no functional equivalent in mammalian cells and, as a consequence, is an attractive target for selective inhibition. This Letter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0889ad7344d0de4eb0df64906929abdc
https://doi.org/10.1016/j.bmcl.2016.01.042
https://doi.org/10.1016/j.bmcl.2016.01.042
Publikováno v:
Antiviral Res
Chronic Hepatitis B Virus infections afflict >250 million people and kill nearly 1 million annually. Current non-curative therapies are dominated by nucleos(t)ide analogs (NAs) that profoundly but incompletely suppress DNA synthesis by the viral reve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6393ebee196e304e4345dd9723e497c5
https://doi.org/10.1016/j.antiviral.2020.104815
https://doi.org/10.1016/j.antiviral.2020.104815