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pro vyhledávání: '"Claire Ogilvie"'
Autor:
Claire Ogilvie, Bo Liang, Shaylan Hill, Taha Rahmatullah, Dongdong Cao, Yunrong Gao, Matthew Kurien, Hyunjun Max Ahn, Anshuman Swain
Publikováno v:
The Journal of Biological Chemistry
The templates for transcription and replication by respiratory syncytial virus (RSV) polymerase are helical nucleocapsids (NCs), formed by viral RNAs that are encapsidated by the nucleoprotein (N). Proper NC assembly is vital for RSV polymerase to en
Autor:
Bo Liang, Shaylan Hill, Yinglong Miao, Dongdong Cao, Priyal Parikh, Amy Yang, Angela Salazar, Claire Ogilvie, Karen Priyadarshini John, Amber Bell, Yunrong Gao, Hyunjun Max Ahn, Shristi Pawnikar, Anshuman Swain, Ju Mi Ha
Publikováno v:
Structure
The M2-1 protein of human respiratory syncytial virus (HRSV) is a transcription anti-terminator that regulates the processivity of the HRSV RNA-dependent RNA polymerase (RdRP). Here, we report a crystal structure of HRSV M2-1 bound to a short positiv