Výsledky vyhledávání - "Claire O. Malécot"

Low voltage-activated channels in rat pulmonary vein cardiomyocytes: coexistence of a non-selective cationic channel and of T-type Ca channels

Autor: Claire O. Malécot

Publikováno v: Pflügers Archiv European Journal of Physiology
Pflügers Archiv European Journal of Physiology, Springer Verlag, 2020, 472, pp.1019-1029. ⟨10.1007/s00424-020-02413-1⟩

International audience; In rat pulmonary vein (PV) cardiomyocytes (CM), norepinephrine (NE) induces an automatic activity consisting of bursts of slow action potentials which depend on Ca2+ (upstroke) and Na+ (inter-burst) channels. Our objective was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc057e22218dfbfbe5047e9ef879f988
https://hal.archives-ouvertes.fr/hal-02881260

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A TTX-Sensitive Resting Na+Permeability Contributes to the Catecholaminergic Automatic Activity in Rat Pulmonary Vein

Autor: Véronique Maupoil, Ian Findlay, Pierre Bredeloux, Claire O. Malécot

Publikováno v: Journal of Cardiovascular Electrophysiology. 26:311-319

Na Channels and Automatic Activity in Rat PV Introduction Ectopic activity arising from pulmonary veins (PV) plays a prominent role in the onset of atrial fibrillation in humans. Rat PV cardiac muscle cells have a lower resting membrane potential (RM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b189892e465f4f8279196601f39f78c1
https://doi.org/10.1111/jce.12572

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SarConfoCal: simultaneous sarcomere length and cytoplasmic calcium measurements for laser scanning confocal microscopy images

Autor: Côme Pasqualin, François Gannier, Pierre Bredeloux, Véronique Maupoil, Angèle Yu, Claire O. Malécot

Publikováno v: Bioinformatics
Bioinformatics, Oxford University Press (OUP), 2017, pp.btw754. ⟨10.1093/bioinformatics/btw754⟩

Summary Simultaneous recordings of myocytes contractility and their cytoplasmic calcium concentration allow powerful studies, particularly on heart failure and other cardiac dysfunctions. Such studies require dedicated and expensive experimental devi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9700fa62c1bb3e63f0ec2f4f642e6ff9
https://hal.archives-ouvertes.fr/hal-02459105

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SarcOptiM for ImageJ: high-frequency online sarcomere length computing on stimulated cardiomyocytes

Autor: Claire O. Malécot, Véronique Maupoil, Pierre Bredeloux, François Gannier, Côme Pasqualin, Angèle Yu

Publikováno v: American Journal of Physiology-Cell Physiology
American Journal of Physiology-Cell Physiology, American Physiological Society, 2016, 311 (2), pp.C277-C283. ⟨10.1152/ajpcell.00094.2016⟩

Accurate measurement of cardiomyocyte contraction is a critical issue for scientists working on cardiac physiology and physiopathology of diseases implying contraction impairment. Cardiomyocytes contraction can be quantified by measuring sarcomere le

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1a872b4311164d973b320e5e50f15fb
https://hal.archives-ouvertes.fr/hal-01406801

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Roles of PKA, PI3K, and cPLA2 in the NO-mediated negative inotropic effect of β2-adrenoceptor agonists in guinea pig right papillary muscles

Autor: Pierre Cosnay, Jacques M. Lignon, François Gannier, Fabien A. Faucher, Claire O. Malécot

Publikováno v: American Journal of Physiology-Cell Physiology. 294:C106-C117

Although β2-adrenoceptors represent 15–25% of β-adrenoceptors in the guinea pig heart, their functionality is controversial. We assessed the inotropic effects of β2-adrenoceptor partial agonists in right papillary muscles. Salbutamol induced a s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8211fdb358ee65bb9cee69264d7959a9
https://doi.org/10.1152/ajpcell.00231.2007

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Antimony-induced cardiomyopathy in guinea-pig and protection byL-carnitine

Autor: Marco Alvarez, Claire O. Malécot, Jacques M. Lignon, François Gannier

Publikováno v: British Journal of Pharmacology. 144:17-27

Antimony (Sb) is the mainstay for the treatment of Leishmaniasis. It has serious, often lethal, cardiovascular side effects. The objective of this study was to examine the effects of Sb treatment upon the electrocardiogram (ECG), myocyte contractilit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ad50f843191cc8c70e31ac99d95542a2
https://doi.org/10.1038/sj.bjp.0706030

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Alternate Splicing in the Cytosolic II–III Loop and the Carboxy Terminus of Human E-type Voltage-Gated Ca Channels: Electrophysiological Characterization of Isoforms

Autor: Andreas Krieger, Toni Schneider, Udo Klöckner, Claire O. Malécot, Jérôme Leroy, Gabriele Pfitzer, Jürgen Hescheler, Alexey Pereverzev

Publikováno v: Molecular and Cellular Neuroscience. 21:352-365

There is growing evidence that Ca v 2.3 (α1E, E-type) transcripts may encode the ion-conducting subunit of a subclass of R-type Ca 2+ channels, a heterogeneous group of channels by definition resistant to blockers of L-, N-, and P/Q-type Ca 2+ chann

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4f4e6cc7e6cf9bda897314d501dc6060
https://doi.org/10.1006/mcne.2002.1179

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Caffeine-induced immobilization of gating charges in isolated guinea-pig ventricular heart cells

Autor: Jérôme Leroy, François Gannier, Claire O. Malécot, Jacques M. Lignon, J Argibay

Publikováno v: British Journal of Pharmacology. 135:721-734

The effects of 10 mM caffeine (CAF) on intramembrane charge movements (ICM) were studied in isolated guinea-pig ventricular heart cells with the whole-cell patch-clamp technique. In the presence of CAF, the properties (voltage dependence, maximum QON

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a84ab2f95675df8b29a0f27897d04c26
https://doi.org/10.1038/sj.bjp.0704520

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