Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Claire Newland"'
Publikováno v:
Muscle & Nerve. 25:715-724
In the Lambert-Eaton myasthenic syndrome (LEMS), immunoglobulin G (IgG) autoantibodies to presynaptic voltage-gated calcium channels (VGCCs) at the neuromuscular junction lead to a reduction in nerve-evoked release of neurotransmitter and muscle weak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bf2a1e1ac5020267a06e3ca70602b92
https://doi.org/10.1002/mus.10087
https://doi.org/10.1002/mus.10087
Publikováno v:
Annals of Neurology. 46:639-647
Acetylcholine receptor (AChR) deficiency is a recessively inherited congenital myasthenic syndrome in which fatigable muscle weakness results from impaired neuromuscular transmission caused by reduced AChR numbers. In mature muscle, AChRs consist of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e84ba674bc0d8148685027b559e8f7ee
https://doi.org/10.1002/1531-8249(199910)46:4<639::aid-ana13>3.0.co
https://doi.org/10.1002/1531-8249(199910)46:4<639::aid-ana13>3.0.co
Publikováno v:
Annals of the New York Academy of Sciences. 841:195-198
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31c6b23ef9af6feb9ec34bba353a29a7
https://doi.org/10.1111/j.1749-6632.1998.tb10927.x
https://doi.org/10.1111/j.1749-6632.1998.tb10927.x
Autor:
Nicholas Willcox, Angela Vincent, Sara Ghorazian, Leslie Jacobson, Paul Plested, John Newsdom-Davis, Cal Maclenan, Jeremy Farrar, Agata Polizzi, Teresa Tang, Claire Newland, David Beeson, Sietske Riemersma
Publikováno v:
Annals of the New York Academy of Sciences. 841:482-496
A new autoimmune disease affecting the neuromuscular junction has been defined. Acquired neuromyotonia is associated with antibodies to voltage-gated potassium channels that act, at least in part, by reducing potassium channel function with resulting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf32fa01a11365bc9149657bb3a31e0
https://doi.org/10.1111/j.1749-6632.1998.tb10968.x
https://doi.org/10.1111/j.1749-6632.1998.tb10968.x
Autor:
Claire Newland, Guy Chauplannaz, John Newsom-Davis, Angela Vincent, Hans Oosterhuis, David Beeson, R Croxen
Publikováno v:
Human Molecular Genetics. 6:767-774
Congenital myasthenic syndromes are a group of rare genetic disorders that compromise neuromuscular transmission. A subset of these disorders, the slow-channel congenital myasthenic syndrome (SCCMS), is dominantly inherited and has been shown to invo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28a8541c72aeb13e3cbff58067edda0f
https://doi.org/10.1093/hmg/6.5.767
https://doi.org/10.1093/hmg/6.5.767
Autor:
R Croxen, John Newsom-Davis, M. Tariq, Alexandra Buckel, Angela Vincent, David Beeson, Catharina Larsson, F. Y. Li, Claire Newland
Publikováno v:
Annals of the New York Academy of Sciences. 841:181-183
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d850ce9c4ef4f088ed5299660a36cb96
https://doi.org/10.1111/j.1749-6632.1998.tb10924.x
https://doi.org/10.1111/j.1749-6632.1998.tb10924.x
Autor:
Sietske Riemersma, John McConville, Agata Polizzi, Paul Plested, Leslie Jacobson, Claire Newland, Werner Hoch, Angela Vincent, Teresa Tang, John Newsom-Davis, David Beeson
Publikováno v:
Cholinergic Mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::054a3fa62005b34d29a4eead771c74ad
https://doi.org/10.3109/9780203493878-35
https://doi.org/10.3109/9780203493878-35
Publikováno v:
European journal of pharmacology. 354(2-3)
The nonsteroidal antioestrogen tamoxifen has been shown to block a number of voltage-gated cation-selective channels but its effect on ligand-gated cation-selective channels has not been studied. We have investigated the action of tamoxifen and the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d67967e9ac0295b4f8041bb76397201
https://pubmed.ncbi.nlm.nih.gov/9754928
https://pubmed.ncbi.nlm.nih.gov/9754928
Autor:
Claire Newland, Ian K. Hart, Christine Morris, Olaf Pongs, Caroline Waters, John Newsom-Davis, David Beeson, Angela Vincent
Publikováno v:
Annals of neurology. 41(2)
Antibody-mediated autoimmunity underlies a diverse range of disorders, particularly in the nervous system where the extracellular domains of ion channels and receptors are especially vulnerable targets. We present here a novel means of detecting auto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f51c4fa215e57a8ac8a010486f547d59
https://pubmed.ncbi.nlm.nih.gov/9029073
https://pubmed.ncbi.nlm.nih.gov/9029073
Publikováno v:
Trends in neurosciences. 20(1)
The neuromuscular junction is the site of several myasthenic ( mys ,muscle; aesthenia , weakness) disorders of autoimmune and genetic origin. The acquired autoimmune conditions are mainly adult-onset and caused by antibodies to specific neuronal and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a13545639cb35891c73e91f5894ab8ea
https://pubmed.ncbi.nlm.nih.gov/9004414
https://pubmed.ncbi.nlm.nih.gov/9004414