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pro vyhledávání: '"Claire N Horvat"'
Autor:
Michelle H Rich, Abigail V Sharrock, Timothy S Mulligan, Frazer Matthews, Alistair S Brown, Hannah R Lee-Harwood, Elsie M Williams, Janine N Copp, Rory F Little, Jenni JB Francis, Claire N Horvat, Luke J Stevenson, Jeremy G Owen, Meera T Saxena, Jeff S Mumm, David F Ackerley
Publikováno v:
bioRxiv
SummaryFunctional screening of environmental DNA (eDNA) libraries is a potentially powerful approach to discover enzymatic “unknown unknowns”, but is usually heavily biased toward the tiny subset of genes preferentially transcribed and translated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a912240b02a0284245439c0f64bc50dc
https://doi.org/10.1101/2023.03.24.534183
https://doi.org/10.1101/2023.03.24.534183
Autor:
Christopher P. Guise, Adam V. Patterson, Janine N. Copp, Elsie M. Williams, Gareth A. Prosser, Jeff B. Smaill, Claire N. Horvat, William A. Denny, David F. Ackerley, Alexandra M. Mowday, Amir Ashoorzadeh, Sophie P. Syddall, Pearl M. Swe
Publikováno v:
Biochemical pharmacology. 85(8)
Two potentially complementary approaches to improve the anti-cancer strategy gene-directed enzyme prodrug therapy (GDEPT) are discovery of more efficient prodrug-activating enzymes, and development of more effective prodrugs. Here we demonstrate the