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of 2
pro vyhledávání: '"Claire Muxworthy"'
Autor:
Sudipto Roy, Claire Davison, Claire Muxworthy, Christian Wolff, Sarah Baxendale, Philip W. Ingham
Publikováno v:
Nature Genetics. 36:88-93
Vertebrate skeletal muscles comprise distinct fiber types that differ in their morphology, contractile function, mitochondrial content and metabolic properties. Recent studies identified the transcriptional coactivator PGC-1alpha as a key mediator of
Autor:
Yusuke Nakagawa, Yoshihiko Kawaguchi, Rebecca C.J. Twells, Claire Muxworthy, Kara M.D. Hunter, Amanda Wilson, Marilyn E. Merriman, Roger D. Cox, Tony Merriman, Francesco Cucca, Patricia A. McKinney, Julian P.H. Shield, Jaakko Tuomilehto, Eva Tuomilehto-Wolf, Constantin Ionesco-Tirgoviste, Lorenza Nisticò, Raffaella Buzzetti, Paolo Pozzilli, null San-Raffaele Family Study, Geir Joner, Eric Thorsby, Dag E. Undlien, Flemming Pociot, Jörn Nerup, Kjersti S. Rönningen, null Bart's-Oxford Family Study Group, Stephen C. Bain, John A. Todd
Publikováno v:
The American Journal of Human Genetics. 63:547-556
Summary Genomewide linkage studies of type 1 diabetes (or insulin-dependent diabetes mellitus [IDDM]) indicate that several unlinked susceptibility loci can explain the clustering of the disease in families. One such locus has been mapped to chromoso