Mutations in TP53 are exclusively associated with del(17p) in multiple myeloma

Autor: Laurence Lodé, Marion Eveillard, Valérie Trichet, Thierry Soussi, Soraya Wuillème, Steven Richebourg, Florence Magrangeas, Norbert Ifrah, Loïc Campion, Catherine Traullé, François Guilhot, Denis Caillot, Gérald Marit, Claire Mathiot, Thierry Facon, Michel Attal, Jean-Luc Harousseau, Philippe Moreau, Stéphane Minvielle, Hervé Avet-Loiseau

Publikováno v: Haematologica, Vol 95, Iss 11 (2010)

Deletion of the 17p13 chromosomal region [del(17p)] is associated with a poor outcome in multiple myeloma. Most of the studies have targeted the TP53 gene for deletion analyses, although no study showed that this gene is the deletion target. In order

Externí odkaz: https://doaj.org/article/4c03e1a31bc8451abc486e77b7b5a3b3

Activité de recherche clinique académique des investigateurs du réseau des Groupes coopérateurs en oncologie (GCO) : bilan et perspectives

Autor: Maryline Vo, Alexandra Langlais, Jean-François Seitz, Christine Delpeut, Etienne Bardet, Khe Hoang Xuan, Bénédicte Votan, Claire Mathiot, Denis Moro-Sibilot, Jean Michon, Corinne Haioun, Gilles Salles, Christophe Louvet, Franck Morin, Claire Dubois, Eric Pujade-Lauraine, Nadejda Vintonenko, Philippe Casassus, Pascal Deschaseaux, Bernard Milleron, Cécile Girault

Publikováno v: Bulletin du Cancer. 104:652-661

Resume Introduction Le Plan Cancer 2014–2019 insiste sur l’importance de la collaboration entre tous les acteurs de la recherche clinique dans la lutte contre le cancer, dont les intergroupes et groupes cooperateurs. Cette enquete avait pour obje

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a17733261208dee813f5afd5913514e4
https://doi.org/10.1016/j.bulcan.2017.05.006

Bortezomib, thalidomide, and dexamethasone with or without daratumumab before and after autologous stem-cell transplantation for newly diagnosed multiple myeloma (CASSIOPEIA): a randomised, open-label, phase 3 study

Autor: Bertrand Arnulf, Lotfi Benboubker, Claire Mathiot, Jérôme J. Lambert, Cécile Sonntag, Pieter Sonneveld, Lixia Pei, Aurore Perrot, Jean Paul Fermand, Karim Belhadj, Pascal Lenain, Matthijs Westerman, Saskia K. Klein, Carla de Boer, William Deraedt, Soraya Wuilleme, Anne-Marie Stoppa, Jessica Vermeulen, Frédérique Orsini-Piocelle, Brigitte Kolb, Jordan M. Schecter, Jean-Pierre Marolleau, Cyrille Hulin, Mark-David Levin, Tobias Kampfenkel, Sen Zhuang, Jill Corre, Christopher Chiu, Jean Fontan, Hervé Avet-Loiseau, Thomas Dejoie, Martine Escoffre-Barbe, Murielle Roussel, Michel Delforge, Jean-Richard Eveillard, Cyrille Touzeau, Lionel Karlin, Tahamtan Ahmadi, Philippe Moreau, Niels W.C.J. van de Donk, Marie C. Béné, Marie-Christiane Vekemans, Sonja Zweegman, Xavier Leleu, Reda Garidi, Hélène Caillon, Mourad Tiab, Margaret Macro, Nathalie Meuleman, Elena Smith, Laurent Garderet, Kon-Siong Jie, Thierry Facon, Denis Caillot, Frédérique Kuhnowski, Annemiek Broijl, Michel Attal, Chantal Doyen

Publikováno v: The Lancet
The Lancet, 2019, 394 (10192), pp.29-38. ⟨10.1016/S0140-6736(19)31240-1⟩
Moreau, P, Attal, M, Hulin, C, Arnulf, B, Belhadj, K, Benboubker, L, Béné, M C, Broijl, A, Caillon, H L, Caillot, D, Corre, J, Delforge, M, Dejoie, T, Doyen, C, Facon, T, Sonntag, C C, Fontan, J, Garderet, L, Jie, K-S, Karlin, L, Kuhnowski, F, Lambert, J R, Leleu, X, Lenain, P, Macro, M, Mathiot, C, Orsini-Piocelle, F, Perrot, A, Stoppa, A-M, van de Donk, N W CJ, Wuilleme, S, Zweegman, S, Kolb, B, Touzeau, C, Roussel, M, Tiab, M, Marolleau, J-P, Meuleman, N, Vekemans, M-C, Westerman, M, Klein, S K, Levin, M-D, Fermand, J P, Escoffre-Barbe, M, Eveillard, J-R, Garidi, R, Ahmadi, T, Zhuang, S, Chiu, C, Pei, L, de Boer, C, Smith, E, Deraedt, W, Kampfenkel, T, Schecter, J, Vermeulen, J, Avet-Loiseau, H & Sonneveld, P 2019, ' Bortezomib, thalidomide, and dexamethasone with or without daratumumab before and after autologous stem-cell transplantation for newly diagnosed multiple myeloma (CASSIOPEIA): a randomised, open-label, phase 3 study ', The Lancet, vol. 394, no. 10192, pp. 29-38 . https://doi.org/10.1016/S0140-6736(19)31240-1
The Lancet, 394(10192), 29-38. Elsevier Limited
Lancet, Vol. 394, no. 10192, p. 29-38 (2019)
Lancet (UK), 394(10192), 29-38. Elsevier Ltd.

Background: Bortezomib, thalidomide, and dexamethasone (VTd) plus autologous stem-cell transplantation is standard treatment in Europe for transplant-eligible patients with newly diagnosed multiple myeloma. We evaluated whether the addition of daratu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbfa6c08ba25919f03b6f545d38d13cf
https://hal-u-picardie.archives-ouvertes.fr/hal-03605015

Lenalidomide, Bortezomib, and Dexamethasone with Transplantation for Myeloma

Autor: Michel, Attal, Valerie, Lauwers-Cances, Cyrille, Hulin, Xavier, Leleu, Denis, Caillot, Martine, Escoffre, Bertrand, Arnulf, Margaret, Macro, Karim, Belhadj, Laurent, Garderet, Murielle, Roussel, Catherine, Payen, Claire, Mathiot, Jean P, Fermand, Nathalie, Meuleman, Sandrine, Rollet, Michelle E, Maglio, Andrea A, Zeytoonjian, Edie A, Weller, Nikhil, Munshi, Kenneth C, Anderson, Paul G, Richardson, Thierry, Facon, Hervé, Avet-Loiseau, Jean-Luc, Harousseau, Philippe, Moreau, P, Zunic

Publikováno v: New England Journal of Medicine
New England Journal of Medicine, Massachusetts Medical Society, 2017, 376 (14), pp.1311-1320. ⟨10.1056/NEJMoa1611750⟩
New England Journal of Medicine, 2017, 376 (14), pp.1311-1320. ⟨10.1056/NEJMoa1611750⟩

International audience; BackgroundHigh-dose chemotherapy plus autologous stem-cell transplantation has been the standard treatment for newly diagnosed multiple myeloma in adults up to 65 years of age. However, promising data on the use of combination

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdc03257c51eb21024f9872b6210446a
https://hal-univ-bourgogne.archives-ouvertes.fr/hal-01557406

IgA kappa/IgA lambda heavy/light chain assessment in the management of patients with IgA myeloma

Autor: Hervé Avet-Loiseau, Suzanna Schraen, Philippe Moreau, Hélène Demarquette, Remy Dulery, Thierry Facon, Salomon Manier, Stephen Harding, Marie Pierre Noel, Guillemette Fouquet, Claire Mathiot, Stéphanie Guidez, Eileen M Boyle, Jean-Luc Faucompré, Marie Odile Petillon, Xavier Leleu, Bernadette Hennache, Sarah Bonnet, Charles Herbaux, Brigitte Onraed

Publikováno v: Cancer. 120:3952-3957

BACKGROUND Accurate quantification of immunoglobulin A (IgA) monoclonal immunoglobulins by serum protein electrophoresis (SPEP) can be difficult and can impact the assessment of response among patients with multiple myeloma (MM). Therefore, there is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ac17b837e7524b4c630809d43cbef1c
https://doi.org/10.1002/cncr.28946