Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Claire M. Smith"'
Autor:
Joseph F. Standing, Laura Buggiotti, Jose Afonso Guerra-Assuncao, Maximillian Woodall, Samuel Ellis, Akosua A. Agyeman, Charles Miller, Mercy Okechukwu, Emily Kirkpatrick, Amy I. Jacobs, Charlotte A. Williams, Sunando Roy, Luz M. Martin-Bernal, Rachel Williams, Claire M. Smith, Theo Sanderson, Fiona B. Ashford, Beena Emmanuel, Zaheer M. Afzal, Adrian Shields, Alex G. Richter, Jienchi Dorward, Oghenekome Gbinigie, Oliver Van Hecke, Mark Lown, Nick Francis, Bhautesh Jani, Duncan B. Richards, Najib M. Rahman, Ly-Mee Yu, Nicholas P. B. Thomas, Nigel D. Hart, Philip Evans, Monique Andersson, Gail Hayward, Kerenza Hood, Jonathan S. Nguyen-Van-Tam, Paul Little, F. D. Richard Hobbs, Saye Khoo, Christopher Butler, David M. Lowe, Judith Breuer, PANORAMIC Virology Group
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Viral clearance, antibody response and the mutagenic effect of molnupiravir has not been elucidated in at-risk populations. Non-hospitalised participants within 5 days of SARS-CoV-2 symptoms randomised to receive molnupiravir (n = 253) or Us
Externí odkaz:
https://doaj.org/article/01afce3eddb24d8aa3b7e67fa19987db
Autor:
Elizabeth F. Maughan, Robert E. Hynds, Adam Pennycuick, Ersilia Nigro, Kate H.C. Gowers, Celine Denais, Sandra Gómez-López, Kyren A. Lazarus, Jessica C. Orr, David R. Pearce, Sarah E. Clarke, Dani Do Hyang Lee, Maximillian N.J. Woodall, Tereza Masonou, Katie-Marie Case, Vitor H. Teixeira, Benjamin E. Hartley, Richard J. Hewitt, Chadwan Al Yaghchi, Gurpreet S. Sandhu, Martin A. Birchall, Christopher O’Callaghan, Claire M. Smith, Paolo De Coppi, Colin R. Butler, Sam M. Janes
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105409- (2022)
Summary: The airway epithelium is a protective barrier that is maintained by the self-renewal and differentiation of basal stem cells. Increasing age is a principle risk factor for chronic lung diseases, but few studies have explored age-related mole
Externí odkaz:
https://doaj.org/article/bc9bfc65a4564f5b8c32bca349dccceb
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract Large numbers of neutrophils migrate into the lungs of children with severe Respiratory Syncytial Virus (RSV) disease. It is unclear how these cells contribute to viral clearance and recovery from infection or whether they contribute to dise
Externí odkaz:
https://doaj.org/article/29555bd932114e02acc71ec074c617a4
Publikováno v:
Viruses, Vol 8, Iss 8, p 237 (2016)
Defective interfering (DI) viruses arise during the replication of influenza A virus and contain a non-infective version of the genome that is able to interfere with the production of infectious virus. In this study we hypothesise that a cloned DI in
Externí odkaz:
https://doaj.org/article/1a77ef1ba10540a6b8d83883ca2d9068
Autor:
Fabio Tommasini, Thomas Benoist, Soichi Shibuya, Maximillian N.J. Woodall, Eleonora Naldi, Jessica C. Orr, Giovanni Giuseppe Giobbe, Elizabeth F. Maughan, Robert E. Hynds, Asllan Gjinovci, J. Ciaran Hutchinson, Owen J. Arthurs, Sam M. Janes, Nicola Elvassore, Claire M. Smith, Federica Michielin, Alessandro Filippo Pellegata, Paolo De Coppi
Lung infections are one of the leading causes of death worldwide, and this situation has been exacerbated by the emergence of COVID-19. Pre-clinical modelling of viral infections has relied on cell cultures that lack 3D structure and the context of l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::213bf01746839c8b9f7c49a9173784bd
https://doi.org/10.1101/2023.02.01.526441
https://doi.org/10.1101/2023.02.01.526441
Publikováno v:
Analytical Chemistry. 94:6089-6096
Precisely controlling the size of engineered biomolecules and pharmaceutical compounds is often critical to their function. Standard methods for size characterization, such as dynamic light scattering or size exclusion chromatography, can be sample i
Autor:
Maximillian Woodall, Ana-Maria Cujba, Kaylee B. Worlock, Katie-Marie Case, Tereza Masonou, Masahiro Yoshida, Krzysztof Polanski, Ni Huang, Rik G. H. Lindeboom, Lira Mamanova, Liam Bolt, Laura Richardson, Samuel Ellis, Machaela Palor, Thomas Burgoyne, Andreia Pinto, Dale Moulding, Timothy D. McHugh, Aarash Saleh, Eliz Kilich, Puja Mehta, Chris O’Callaghan, Jie Zhou, Wendy Barclay, Paolo De Coppi, Colin R. Butler, Heloise Vinette, Sunando Roy, Judith Breuer, Rachel C. Chambers, Wendy E. Heywood, Kevin Mills, Robert E. Hynds, Sarah A. Teichmann, Kerstin B. Meyer, Marko Z. Nikolić, Claire M. Smith
Children infected with SARS-CoV-2 rarely progress to respiratory failure, but the risk of mortality in infected people over 85 years of age remains high, despite vaccination and improving treatment options. Here, we take a comprehensive, multidiscipl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d879062a84c842d555af5dd10e4eba88
https://doi.org/10.1101/2023.01.16.524211
https://doi.org/10.1101/2023.01.16.524211
Publikováno v:
The Journal of antimicrobial chemotherapy. 78(1)
Conventional cell culture systems involve growing cells in stationary cultures in the presence of growth medium containing various types of supplements. At confluency, the cells are divided and further expanded in new culture dishes. This passage fro
Autor:
Caitlyn Adkins, Claire M Smith
Publikováno v:
Poster Presentations.
Background Advance care planning (ACP) empowers people to think about what is important to them and provides an opportunity to record their wishes for future care (Gold Standards Framework, 2018). NICE recognise that people growing older with a learn
Publikováno v:
Fertility and Sterility. 114:e81-e82