Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Claire M. Schmerberg"'
Autor:
Mei Huang, William C. Wetsel, Bryan L. Roth, Herbert Y. Meltzer, Jianjun Cheng, Vladimir M. Pogorelov, Ramona M. Rodriguiz, Claire M. Schmerberg, Alan P. Kozikowski
Publikováno v:
Neuropsychopharmacology. 42:2163-2177
All FDA-approved antipsychotic drugs (APDs) target primarily dopamine D2 or serotonin (5-HT2A) receptors, or both; however, these medications are not universally effective, they may produce undesirable side effects, and provide only partial ameliorat
Autor:
Hui Ye, Adam D. Catherman, Chenxi Jia, Zichuan Zhang, Paul M. Thomas, Neil L. Kelleher, Claire M. Schmerberg, Jingxin Wang, Lingjun Li
Publikováno v:
Journal of Proteome Research. 14:4776-4791
Decapod crustaceans are important animal models for neurobiologists due to their relatively simple nervous systems with well-defined neural circuits and extensive neuromodulation by a diverse set of signaling peptides. However, biochemical characteri
Autor:
Meng Chen, William C. Wetsel, Marc G. Caron, Jian Jin, Ramona M. Rodriguiz, Su Mi Park, Russell S Dulman, Claire M. Schmerberg
Publikováno v:
Neuropsychopharmacology. 41:704-715
Current antipsychotic drugs (APDs) show efficacy with positive symptoms, but are limited in treating negative or cognitive features of schizophrenia. Whereas all currently FDA-approved medications target primarily the dopamine D2 receptor (D2R) to in
Publikováno v:
ACS Chemical Neuroscience
Food consumption is an important behavior that is regulated by an intricate array of neuropeptides (NPs). Although many feeding-related NPs have been identified in mammals, precise mechanisms are unclear and difficult to study in mammals, as current
Autor:
Claire M. Schmerberg, Lingjun Li
Publikováno v:
Protein & Peptide Letters. 20:681-694
A number of unique challenges are inherent to the study of neuropeptides (NPs), both in determining their molecular structure and their function. Traditional studies follow a model in which novel NPs are discovered and identified, then investigated f
Autor:
Claire M. Schmerberg, Lingjun Li
Publikováno v:
Analytical Chemistry. 85:915-922
Microdialysis (MD) is a useful sampling tool for many applications due to its ability to permit sampling from an animal concurrent with normal activity. MD is of particular importance in the field of neuroscience, in which it is used to sample neurot
Autor:
Giulio Vistoli, Patrick M. Giguère, Wei Lv, William C. Wetsel, Jianjun Cheng, Claire M. Schmerberg, Alan P. Kozikowski, Hendra Gunosewoyo, Bryan L. Roth, Ramona M. Rodriguiz, Arsen Gaisin, Vladimir M. Pogorelov, Oluseye K. Onajole
Publikováno v:
Journal of medicinal chemistry. 58(4)
The discovery of a new series of compounds that are potent, selective 5-HT2C receptor agonists is described herein as we continue our efforts to optimize the 2-phenylcyclopropylmethylamine scaffold. Modifications focused on the alkoxyl substituent pr
Publikováno v:
The Analyst. 140(11)
Neuropeptides (NPs), a unique and highly important class of signaling molecules across the animal kingdom, have been extensively characterized in the neuronal tissues of various crustaceans. Because many NPs are released into circulating fluid (hemol
Autor:
William C. Wetsel, Jian Jin, Su Mi Park, Claire M. Schmerberg, Vladimir M. Pogorelov, Marc G. Caron, Ramona M. Rodriguiz
Publikováno v:
International Journal of Neuropsychopharmacology