Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Claire M. Perks"'
Publikováno v:
Cancer Medicine, Vol 12, Iss 13, Pp 14426-14439 (2023)
Abstract Background The overall survival of IDH‐wildtype glioblastoma patients is poor despite best available treatments. There is an urgent need for new biomarkers to inform more precise disease stratification. Previous studies have identified ins
Externí odkaz:
https://doaj.org/article/6b09adc5921840d8be5ef5568a10ade7
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
Brain tumours reduce life expectancy for an average of 20 years per patient, the highest of any cancer. A third of brain tumour patients visit their GP at least five times before diagnosis and many of those are diagnosed late through emergency depart
Externí odkaz:
https://doaj.org/article/e9850a70bf2945b6a420c2144db0dfea
Autor:
Claire M. Perks, Antonino Belfiore
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/95d8e7f39baf427c932e97bb30ac549d
Autor:
Kalina M. Biernacka, Dinesh Giri, Katherine Hawton, Francisca Segers, Claire M. Perks, Julian P. Hamilton-Shield
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
There have been over 100 cases of Rapid-onset obesity with hypothalamic dysfunction, hypoventilation, and autonomic dysregulation (ROHHAD) syndrome reported, but there is currently no curative treatment for children with this condition. We aimed to b
Externí odkaz:
https://doaj.org/article/536b31e27781458d8816f8545ddfff01
Autor:
Si Fang, James Yarmolinsky, Dipender Gill, Caroline J. Bull, Claire M. Perks, George Davey Smith, Tom R. Gaunt, Tom G. Richardson
Publikováno v:
PLoS Medicine, Vol 20, Iss 1 (2023)
Background Prostate cancer (PrCa) is the second most prevalent malignancy in men worldwide. Observational studies have linked the use of low-density lipoprotein cholesterol (LDL-c) lowering therapies with reduced risk of PrCa, which may potentially b
Externí odkaz:
https://doaj.org/article/d8607280901c4b5996a4aa7a30daf747
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/0f9f354605d34e6faa1e3fdb828fc7ed
Autor:
Claire M. Perks, Antonino Belfiore
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/96228e299f064a4aa47add8515832206
Autor:
Simon Uzor, Sean R. Porazinski, Ling Li, Bethany Clark, Masahiko Ajiro, Kei Iida, Masatoshi Hagiwara, Abdullah A. Alqasem, Claire M. Perks, Ian D. Wilson, Sebastian Oltean, Michael R. Ladomery
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Dysregulation of alternative splicing is a feature of cancer, both in aetiology and progression. It occurs because of mutations in splice sites or sites that regulate splicing, or because of the altered expression and activity of splice fact
Externí odkaz:
https://doaj.org/article/1595aa359a334c009f784001b7ba6977
Autor:
Shin-Ichiro Takahashi, Claire M. Perks
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/18d13e8743d6415fa2c44aca5d02f51d
Autor:
Abigail Harland, Xia Liu, Mattia Ghirardello, M. Carmen Galan, Claire M. Perks, Kathreena M. Kurian
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Glioma stem-like cells (GSCs) were first described as a population which may in part be resistant to traditional chemotherapeutic therapies and responsible for tumour regrowth. Knowledge of the underlying metabolic complexity governing GSC growth and
Externí odkaz:
https://doaj.org/article/343bfe4cdb0d40628831d705a914bc96