Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Claire M. Perks"'
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
Brain tumours reduce life expectancy for an average of 20 years per patient, the highest of any cancer. A third of brain tumour patients visit their GP at least five times before diagnosis and many of those are diagnosed late through emergency depart
Externí odkaz:
https://doaj.org/article/e9850a70bf2945b6a420c2144db0dfea
Publikováno v:
Cancer Medicine, Vol 12, Iss 13, Pp 14426-14439 (2023)
Abstract Background The overall survival of IDH‐wildtype glioblastoma patients is poor despite best available treatments. There is an urgent need for new biomarkers to inform more precise disease stratification. Previous studies have identified ins
Externí odkaz:
https://doaj.org/article/6b09adc5921840d8be5ef5568a10ade7
Publikováno v:
Cancers, Vol 16, Iss 11, p 2113 (2024)
The role if insulin-like growth factor binding protein-2 (IGFBP-2) in mediating chemoresistance in breast cancer cells has been demonstrated, but the mechanism of action is unclear. This study aimed to further investigate the role of IGFBP-2 in the D
Externí odkaz:
https://doaj.org/article/4a2b17e9111a45fdb3d3673d3c8b79d3
Autor:
Emily Gill, Claire M. Perks
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1557 (2024)
Bladder cancer is the tenth most common cancer and is a significant burden on health care services worldwide, as it is one of the most costly cancers to treat per patient. This expense is due to the extensive treatment and follow-ups that occur with
Externí odkaz:
https://doaj.org/article/8783664accb44c898376e8efb9ea9ecf
Autor:
Claire M. Perks, Antonino Belfiore
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/95d8e7f39baf427c932e97bb30ac549d
Autor:
Kalina M. Biernacka, Dinesh Giri, Katherine Hawton, Francisca Segers, Claire M. Perks, Julian P. Hamilton-Shield
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
There have been over 100 cases of Rapid-onset obesity with hypothalamic dysfunction, hypoventilation, and autonomic dysregulation (ROHHAD) syndrome reported, but there is currently no curative treatment for children with this condition. We aimed to b
Externí odkaz:
https://doaj.org/article/536b31e27781458d8816f8545ddfff01
Autor:
Claire M. Perks
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16969 (2023)
The insulin-like growth factor axis is a multifaceted, complex system that comprises two ligands, IGF-I and IGF-II, receptors (IGF-1R, IGF-IIR, insulin receptor isoforms IR-A and B, and hybrid receptors) six high affinity IGF-binding proteins (IGFBPs
Externí odkaz:
https://doaj.org/article/9ad43f60f8594eb584218f0a6c76633e
Autor:
Si Fang, James Yarmolinsky, Dipender Gill, Caroline J. Bull, Claire M. Perks, George Davey Smith, Tom R. Gaunt, Tom G. Richardson
Publikováno v:
PLoS Medicine, Vol 20, Iss 1 (2023)
Background Prostate cancer (PrCa) is the second most prevalent malignancy in men worldwide. Observational studies have linked the use of low-density lipoprotein cholesterol (LDL-c) lowering therapies with reduced risk of PrCa, which may potentially b
Externí odkaz:
https://doaj.org/article/d8607280901c4b5996a4aa7a30daf747
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/0f9f354605d34e6faa1e3fdb828fc7ed
Autor:
Claire M. Perks, Antonino Belfiore
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/96228e299f064a4aa47add8515832206