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pro vyhledávání: '"Claire M. Holden"'
Autor:
Bethany J. Bogan, Holly C. Williams, Claire M. Holden, Vraj Patel, Giji Joseph, Christopher Fierro, Hugo Sepulveda, W. Robert Taylor, Amir Rezvan, Alejandra San Martin
Publikováno v:
Cells, Vol 13, Iss 8, p 658 (2024)
Vascular smooth muscle cells (VSMCs), in their contractile and differentiated state, are fundamental for maintaining vascular function. Upon exposure to cholesterol (CHO), VSMCs undergo dedifferentiation, adopting characteristics of foam cells—lipi
Externí odkaz:
https://doaj.org/article/4732a12e4c74475f9b2047336dfa930c
Autor:
Felipe Paredes, Holly C. Williams, Izabela Suster, Macarena Tejos, Roberto Fuentealba, Bethany Bogan, Claire M. Holden, Alejandra San Martin
Publikováno v:
Free Radical Biology and Medicine. 195:283-297
The polymerase delta interacting protein 2 (Poldip2) is a nuclear-encoded mitochondrial protein required for oxidative metabolism. Under hypoxia, Poldip2 expression is repressed by an unknown mechanism. Therefore, low levels of Poldip2 are required t