Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Claire M. Dording"'
Autor:
Peter A. Barbuti, Jochen Ohnmacht, Bruno F. R. Santos, Paul M. Antony, François Massart, Gérald Cruciani, Claire M. Dording, Lukas Pavelka, Nicolas Casadei, Yong-Jun Kwon, Rejko Krüger
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Parkinson’s disease (PD) is characterised by the degeneration of A9 dopaminergic neurons and the pathological accumulation of alpha-synuclein. The p.A30P SNCA mutation generates the pathogenic form of the alpha-synuclein protein causing an
Externí odkaz:
https://doaj.org/article/fa5d1e8ffb404e52b22f63112205442d
Autor:
Ibrahim Boussaad, Gérald Cruciani, Silvia Bolognin, Paul Antony, Claire M. Dording, Yong-Jun Kwon, Peter Heutink, Eugenio Fava, Jens C. Schwamborn, Rejko Krüger
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Patient-derived cellular models become an increasingly powerful tool to model human diseases for precision medicine approaches. The identification of robust cellular disease phenotypes in these models paved the way towards high throughput sc
Externí odkaz:
https://doaj.org/article/7839939082c44d75981d01067b8f8bf2
Autor:
Peter A. Barbuti, Bruno F.R. Santos, Claire M. Dording, Gérald Cruciani, François Massart, Andreas Hummel, Rejko Krüger
Publikováno v:
Stem Cell Research, Vol 48, Iss , Pp 101951- (2020)
Dermal fibroblasts from a patient carrying a heterozygous c.88G > C mutation in the SNCA gene that encodes alpha-synuclein were reprogrammed to pluripotency by retroviruses. This pathogenic mutation generates the p.A30P form of the alpha-synuclein pr
Externí odkaz:
https://doaj.org/article/662f63ea616f4df0a20f8df948b5d3ac
Autor:
Bruno F.R. Santos, Peter A. Barbuti, Claire M. Dording, Jochen Ohnmacht, Gérald Cruciani, Lukas Pavelka, Yong-Jun Kwon, Paul Antony, Nicolas Casadei, Rejko Krüger, François Massart
Publikováno v:
Scientific Reports
info:eu-repo/grantAgreement/EC/H2020/692320
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
info:eu-repo/grantAgreement/EC/H2020/692320
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Parkinson’s disease (PD) is characterised by the degeneration of A9 dopaminergic neurons and the pathological accumulation of alpha-synuclein. The p.A30P SNCA mutation generates the pathogenic form of the alpha-synuclein protein causing an autosoma
Autor:
François Massart, Lukas Pavelka, Peter A. Barbuti, Yong-Jun Kwon, Gérald Cruciani, Paul Antony, Claire M. Dording, Bruno F.R. Santos, Rejko Krueger
Parkinson’s disease is characterised by the degeneration of A9 dopaminergic neurons and the pathological accumulation of alpha-synuclein. In a patient-derived stem cell model, we have generated dopaminergic neurons from an individual harbouring the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7131e3934f6bffb0a3bd800011b5b103
https://doi.org/10.1101/2020.11.05.369389
https://doi.org/10.1101/2020.11.05.369389
Autor:
Peter A. Barbuti, Jens Christian Schwamborn, Gérald Cruciani, Claire M. Dording, Paul Antony, Jonathan Arias, Bruno F.R. Santos, Rejko Krüger, François Massart
Publikováno v:
Cells
Volume 9
Issue 9
Cells, Vol 9, Iss 2065, p 2065 (2020)
Volume 9
Issue 9
Cells, Vol 9, Iss 2065, p 2065 (2020)
The generation of isogenic induced pluripotent stem cell (iPSC) lines using CRISPR-Cas9 technology is a technically challenging, time-consuming process with variable efficiency. Here we use fluorescence-activated cell sorting (FACS) to sort biallelic
Autor:
Jens Christian Schwamborn, Paul Antony, Gérald Cruciani, Jonathan Arias, Claire M. Dording, Bruno F.R. Santos, Peter A. Barbuti, Rejko Krüger, François Massart
The generation of isogenic induced pluripotent stem cell (iPSC) lines using CRISPR-Cas9 technology is a technically challenging, time-consuming process with variable efficiency. Here we use fluorescence-activated cell sorting (FACS) to sort biallelic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e016805275cb252643147134a2da20a
https://doi.org/10.20944/preprints202005.0001.v1
https://doi.org/10.20944/preprints202005.0001.v1
Autor:
Gérald Cruciani, Claire M. Dording, Andreas Hummel, Rejko Krüger, François Massart, Peter A. Barbuti, Bruno F.R. Santos
Publikováno v:
Stem Cell Research, Vol 48, Iss, Pp 101951-(2020)
Dermal fibroblasts from a patient carrying a heterozygous c.88G > C mutation in the SNCA gene that encodes alpha-synuclein were reprogrammed to pluripotency by retroviruses. This pathogenic mutation generates the p.A30P form of the alpha-synuclein pr