Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Claire M. Doherty"'
Autor:
Claire M. Doherty, Paige R. Patterson, Julie A. Emeanuwa, Jessica Belmares Ortega, Barbara A. Fox, David J. Bzik, Eric Y. Denkers
Publikováno v:
mBio, Vol 15, Iss 11 (2024)
ABSTRACT As a model organism in the study of immunity to infection, Toxoplasma gondii has been instrumental in establishing key principles of host anti-microbial defense and its regulation. Here, we employed an attenuated uracil auxotroph strain of T
Externí odkaz:
https://doaj.org/article/e4fc1f9b3a5741efafd95bfc8cb21f30
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10, p e1009970 (2021)
Toxoplasma gondii is an orally acquired pathogen that induces strong IFN-γ based immunity conferring protection but that can also be the cause of immunopathology. The response in mice is driven in part by well-characterized MyD88-dependent signaling
Externí odkaz:
https://doaj.org/article/414ff491d4484a61aadcd0d8355b9edc
Autor:
Heather L Mercer, Lindsay M Snyder, Claire M Doherty, Barbara A Fox, David J Bzik, Eric Y Denkers
Publikováno v:
PLoS Pathogens, Vol 16, Iss 5, p e1008572 (2020)
The apicomplexan Toxoplasma gondii induces strong protective immunity dependent upon recognition by Toll-like receptors (TLR)11 and 12 operating in conjunction with MyD88 in the murine host. However, TLR11 and 12 proteins are not present in humans, i
Externí odkaz:
https://doaj.org/article/1158ee5894a54cd9af1900b0919a7d3c
Publikováno v:
ImmunoHorizons. 6:660-670
iToxoplasma gondii/iinduces strong IFN-γ-based immunity. Innate lymphoid cells (ILC), in particular ILC1, are an important innate source of this protective cytokine during infection. Our objective was to determine how MyD88-dependent signaling influ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5962b253e16303eff6ca082ef3a36c3
https://doi.org/10.4049/immunohorizons.2200070
https://doi.org/10.4049/immunohorizons.2200070
Publikováno v:
Parasite immunologyREFERENCES. 44(1-2)
Signalling by IFN-y and CD40 is known to trigger anti-microbial activity in macrophages infected with Toxoplasma gondii, but their effects on infected neurons are less well known. Here, we compared how stimulation with IFN-y and an agonistic anti-CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6279cb8e8aeaa66a811ef6a9c9ee0834
https://pubmed.ncbi.nlm.nih.gov/34762755
https://pubmed.ncbi.nlm.nih.gov/34762755
Autor:
Heather Lynn Mercer, Lindsay M. Snyder, Kayla L. Menard, Claire M. Doherty, David J. Bzik, Barbara A. Fox, Eric Y. Denkers
Publikováno v:
The Journal of Immunology. 206:112.13-112.13
The apicomplexan Toxoplasma gondii induces strong protective immunity in part dependent upon recognition by Toll-like receptors (TLR) 11 and 12 operating in conjunction with MyD88 in the murine host. However, these TLR are not present in humans, prom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ff5a4a849b63fc8d205412c5da7da89
https://doi.org/10.4049/jimmunol.206.supp.112.13
https://doi.org/10.4049/jimmunol.206.supp.112.13
Publikováno v:
The Journal of Immunology. 206:16.15-16.15
Toxoplasma gondii is an orally acquired pathogen that induces strong, protective IFN-γ based immunity. The response in mice is driven in part by well-characterized MyD88-dependent signaling pathways. The objective of this study was to determine the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fec7442654155a1418a0c7cf440f5c02
https://doi.org/10.4049/jimmunol.206.supp.16.15
https://doi.org/10.4049/jimmunol.206.supp.16.15
Autor:
Barbara A. Fox, Heather L. Mercer, Claire M. Doherty, Eric Y. Denkers, David J. Bzik, Lindsay M. Snyder
Publikováno v:
PLoS Pathogens, Vol 16, Iss 5, p e1008572 (2020)
PLoS Pathogens
PLoS Pathogens
The apicomplexan Toxoplasma gondii induces strong protective immunity dependent upon recognition by Toll-like receptors (TLR)11 and 12 operating in conjunction with MyD88 in the murine host. However, TLR11 and 12 proteins are not present in humans, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7fd8112a64b7e838e1544eb56f78ac2
https://doi.org/10.1371/journal.ppat.1008572
https://doi.org/10.1371/journal.ppat.1008572