Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Claire M Banwell"'
Autor:
Myrsini Kaforou, Victoria J Wright, Tolu Oni, Neil French, Suzanne T Anderson, Nonzwakazi Bangani, Claire M Banwell, Andrew J Brent, Amelia C Crampin, Hazel M Dockrell, Brian Eley, Robert S Heyderman, Martin L Hibberd, Florian Kern, Paul R Langford, Ling Ling, Marc Mendelson, Tom H Ottenhoff, Femia Zgambo, Robert J Wilkinson, Lachlan J Coin, Michael Levin
Publikováno v:
PLoS Medicine, Vol 10, Iss 10, p e1001538 (2013)
BackgroundA major impediment to tuberculosis control in Africa is the difficulty in diagnosing active tuberculosis (TB), particularly in the context of HIV infection. We hypothesized that a unique host blood RNA transcriptional signature would distin
Externí odkaz:
https://doaj.org/article/c9a7e833bb4b4edbb6bcb66204d78681
Publikováno v:
Nucleic Acids Research
The main regulator of the human tumor suppresser gene p21(waf1/cip1) is the transcription factor p53, but more recently it has been suggested to be a primary anti-proliferative target for the nuclear receptor VDR in the presence of its ligand 1alpha,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bea4e9b40809910e4aefdfb38a738f1
https://doi.org/10.1093/nar/gkj460
https://doi.org/10.1093/nar/gkj460
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. :245-249
Proliferation of the non-malignant breast epithelial cell line, MCF-12A, is sensitively and completely inhibited by 1alpha,25-dihydroxyvitamin D(3) (1alpha,25(OH)(2)D(3)) (ED90 = 70 nM), We used real time RT-PCR to demonstrate that the relative resis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f89952aabdb1fd80397e5ece4fa8b384
https://doi.org/10.1016/j.jsbmb.2004.03.081
https://doi.org/10.1016/j.jsbmb.2004.03.081
Publikováno v:
European Journal of Immunology. 30:2125-2129
T cell precursor development depends upon poorly defined interactions between thymocyte precursors and stromal cells involving cell surface molecules, extracellular matrix (ECM) components and soluble growth factors. To determine whether presentation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65309f9ffdecb65d7599fd7aa9f2bf46
https://doi.org/10.1002/1521-4141(2000)30:8<2125::aid-immu2125>3.0.co
https://doi.org/10.1002/1521-4141(2000)30:8<2125::aid-immu2125>3.0.co
Autor:
Dominique J. Pepper, Robert J. Wilkinson, Paul R. Langford, Tolu Oni, Katalin A. Wilkinson, Hannah P. Gideon, Kathryn J. Wood, Claire M. Banwell, Melissa Hamilton, Ronnett Seldon
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 8, p e71351 (2013)
PLoS One
PLoS ONE, Vol 8, Iss 8, p e71351 (2013)
PLoS One
Studies on Mycobacterium tuberculosis (MTB) antigens are of interest in order to improve vaccine efficacy and to define biomarkers for diagnosis and treatment monitoring. The methodologies used for these investigations differ greatly between laborato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f11365f1092bcf1fc8576c2a6115f44b
http://europepmc.org/articles/PMC3738639
http://europepmc.org/articles/PMC3738639
Publikováno v:
Breast cancer research and treatment. 104(2)
Complete or partial inability to sense and repair DNA damage increases the risk of developing cancer. The ataxia telangiectasia mutated (ATM) protein kinase has a crucial role in response to DNA double-strand breaks. Hereditary mutations in the ATM g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a45dd95cf2294a66e134fc7922c31b84
https://pubmed.ncbi.nlm.nih.gov/17061036
https://pubmed.ncbi.nlm.nih.gov/17061036
Publikováno v:
Anticancer research. 26(4A)
The ligand-mediated switch from binding co-repressor to co-activator complexes is central to the transcriptional actions of the vitamin D receptor (VDR) and other nuclear receptors. The capacity of deregulated co-repressors to attenuate the responsiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7bcc51b15347d0fa7debe2ee8604adf3
https://pubmed.ncbi.nlm.nih.gov/16886664
https://pubmed.ncbi.nlm.nih.gov/16886664
Autor:
Michelle Guy, Claire M. Banwell, Janine Mansi, Laura P. O'Neill, Kay W. Colston, Moray J. Campbell, Paul M. Stewart, Alice E. Miles, Milan R. Uskokovic, Donia P. MacCartney, Bryan M. Turner
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 12(7 Pt 1)
Purpose: We hypothesized that deregulated corepressor actions, with associated histone deacetylation activity, epigenetically suppressed vitamin D receptor (VDR) responsiveness and drives resistance towards 1α,25-dihydroxyvitamin D3. Experimental De
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d97d180a40035fc92326231571acc22
https://pubmed.ncbi.nlm.nih.gov/16609009
https://pubmed.ncbi.nlm.nih.gov/16609009
Autor:
Kay W. Colston, Claire M. Banwell, Kelly Townsend, Michelle Guy, Janine Mansi, Martin Hewison, Paul M. Stewart, Moray J. Campbell
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 11(9)
Purpose: Vitamin D seems to exert a protective effect against common cancers, although this does not correlate with circulating levels of active 1,25-dihydroxyvitamin D3 [1,25(OH)2D3], indicating a more localized activation of vitamin D. The aim of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5c899a654f9c0c8669033294baf0948
https://pubmed.ncbi.nlm.nih.gov/15867263
https://pubmed.ncbi.nlm.nih.gov/15867263
Publikováno v:
Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer. 164
Breast and prostate cancer are leading causes of cancer death in the Western world. Hormone ablation is the primary therapy for invasive disease, but the tumour often recurs in an androgen or oestrogen receptor negative form for which novel therapies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c28c80abe71dcf0b024b63920c84dfb6
https://pubmed.ncbi.nlm.nih.gov/12899515
https://pubmed.ncbi.nlm.nih.gov/12899515