Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Claire L. Holness"'
Autor:
Claire L. Holness, Julia H. Spragg, Jonathan Fawcett, Joanne Saunders, Christopher D. Buckley, David Simmons, Ian N. Bird, Adrian L. Harris
Publikováno v:
The Journal of Cell Biology
CD31 is a member of the immunoglobulin superfamily consisting of six Ig-related domains. It is constitutively expressed by platelets, monocytes, and some lymphocytes, but at tenfold higher levels on vascular endothelial cells. CD31 has both homotypic
Autor:
David Simmons, Amanda J. Littler, Claire L. Holness, Alison McDowall, Nancy Hogg, Paul A. Bates, David Bossy, Christopher D. Buckley
Publikováno v:
Journal of Biological Chemistry. 270:877-884
Intercellular adhesion molecule 3 (ICAM-3, CD50) is a member of the immunoglobulin superfamily and is a constitutively expressed ligand for the leukocyte integrin LFA-1 (CD11a/CD18). ICAM-3 is expressed at high levels by all resting leukocyte populat
Publikováno v:
The Journal of Cell Biology
To analyze the binding requirements of LFA-1 for its two most homologous ligands, ICAM-1 and ICAM-3, we compared the effects of various LFA-1 activation regimes and a panel of anti-LFA-1 mAbs in T cell binding assays to ICAM-1 or ICAM-3 coated on pla
Publikováno v:
Journal of Biological Chemistry. 268:9661-9666
Macrosialin is a heavily glycosylated transmembrane protein of 87-115 kDa, highly and specifically expressed by mouse tissue macrophages, and to a lesser extent by dendritic cells. We have isolated cDNA clones encoding macrosialin from a thioglycolla
Publikováno v:
Virology. 193:672-679
The location of nucleotide sequences important in determining the extent of cowpea mosaic virus M-RNA accumulation in cowpea protoplasts has been analyzed by deletion mutagenesis of full-length cDNA clones from which infectious transcripts can be pro
Autor:
David Simmons, Claire L. Holness
Publikováno v:
Blood. 81:1607-1613
CD68 is a 110-Kd transmembrane glycoprotein of unknown function highly expressed by human monocytes and tissue macrophages. We have isolated cDNA clones encoding CD68 from a U937 cDNA library by transient expression in COS cells and panning with the
Autor:
Amanda J. Littler, Nicholas Murray, Christopher D. Buckley, David Simmons, David Bossy, Claire L. Holness, Ian Collins
Publikováno v:
European journal of immunology. 25(2)
Intercellular adhesion molecule-3 (ICAM-3, CD50), a member of the immunoglobulin gene superfamily, is a major ligand for the lymphocyte function-associated antigen 1 (LFA-1, CD18/CD11a) in the resting immune system and plays a role as a signaling and
Autor:
Claire L. Holness, David L. Simmons
Publikováno v:
Journal of cell science. 107
Publikováno v:
Cell adhesion and communication. 2(3)
Advances in cell adhesion research have often been linked to technological advances. The development of monoclonal antibody technology allowed the definition of the molecular components of cell adhesion and pointed to the complexity of the leukocyte