Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Claire L Streatfield"'
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e34259 (2012)
We recently showed that hypoxia-inducible factor 1 (HIF-1) plays a crucial role in the pro-allergic functions of human basophils by transcriptional control of energy metabolism via glycolysis as well as directly triggering expression of the angiogeni
Externí odkaz:
https://doaj.org/article/5d1983117cd6428b9f3aa63b052f8d5f
Publikováno v:
European Journal of Immunology. 39:3511-3519
Basophils play a pivotal role in regulating chronic allergic inflammation as well as angiogenesis. Here, we show for the first time that IgE-mediated activation of primary human basophils results in protein accumulation of the α-subunit of hypoxia-i
Autor:
Claire L. Streatfield, Bernhard F. Gibbs, Inna M. Yasinska, Vadim V. Sumbayev, Abraham E. Oniku
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 3, p e34259 (2012)
PLoS ONE, Vol 7, Iss 3, p e34259 (2012)
We recently showed that hypoxia-inducible factor 1 (HIF-1) plays a crucial role in the pro-allergic functions of human basophils by transcriptional control of energy metabolism via glycolysis as well as directly triggering expression of the angiogeni
Publikováno v:
Expert review of clinical immunology. 5(6)
Basophils are relatively rare leukocytes that potentially play a role in both systemic anaphylaxis and, owing to their ability to migrate from the blood into various other tissues, in more localized aspects of allergic inflammation. Given their great
Publikováno v:
European journal of immunology. 39(12)
Basophils play a pivotal role in regulating chronic allergic inflammation as well as angiogenesis. Here, we show for the first time that IgE-mediated activation of primary human basophils results in protein accumulation of the alpha-subunit of hypoxi
Autor:
Ed McGowan, Rachel Rosenthal, Andrew Fiore-Gartland, Gladys Macharia, Sheila Balinda, Anne Kapaata, Gisele Umviligihozo, Erick Muok, Jama Dalel, Claire L. Streatfield, Helen Coutinho, Dario Dilernia, Daniela C. Monaco, David Morrison, Ling Yue, Eric Hunter, Morten Nielsen, Jill Gilmour, Jonathan Hare
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Predictive models are becoming more and more commonplace as tools for candidate antigen discovery to meet the challenges of enabling epitope mapping of cohorts with diverse HLA properties. Here we build on the concept of using two key parameters, div
Externí odkaz:
https://doaj.org/article/493f151d155947d8b8782e91a188310e