Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Claire L Shovlin"'
Autor:
Inês G Mollet, Dilipkumar Patel, Fatima S Govani, Adam Giess, Koralia Paschalaki, Manikandan Periyasamy, Elaine C Lidington, Justin C Mason, Michael D Jones, Laurence Game, Simak Ali, Claire L Shovlin
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0147990 (2016)
BACKGROUND:Spontaneous reports from patients able to report vascular sequelae in real time, and recognition that serum non transferrin bound iron may reach or exceed 10μmol/L in the blood stream after iron tablets or infusions, led us to hypothesize
Externí odkaz:
https://doaj.org/article/2124d7e947f44e82b62022015bd7087c
Autor:
Claire L Shovlin
Publikováno v:
Frontiers in Genetics, Vol 6 (2015)
Hereditary hemorrhagic telangiectasia (HHT) is mechanistically and therapeutically challenging, not only because of the molecular and cellular perturbations that generate vascular abnormalities, but also the modifications to circulatory physiology th
Externí odkaz:
https://doaj.org/article/f99ee8b310cc48e29977819331e3bf1a
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90777 (2014)
BackgroundOxygen, haemoglobin and cardiac output are integrated components of oxygen transport: each gram of haemoglobin transports 1.34 mls of oxygen in the blood. Low arterial partial pressure of oxygen (PaO2), and haemoglobin saturation (SaO2), ar
Externí odkaz:
https://doaj.org/article/808769cc988441b2bfe0ab93fd467bd3
Autor:
Claire L Shovlin, Basel Chamali, Vatshalan Santhirapala, John A Livesey, Gillian Angus, Richard Manning, Michael A Laffan, John Meek, Hannah C Tighe, James E Jackson
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88812 (2014)
BACKGROUND: Pulmonary first pass filtration of particles marginally exceeding ∼7 µm (the size of a red blood cell) is used routinely in diagnostics, and allows cellular aggregates forming or entering the circulation in the preceding cardiac cycle
Externí odkaz:
https://doaj.org/article/47ad01d573ee4ec08b399a091832c9c0
Autor:
Atieh Modarresi, Claire L. Shovlin
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/4b9e7bb8f62b423d8debd42f5d6df93e
Autor:
Helen Finnamore, James Le Couteur, Mary Hickson, Mark Busbridge, Kevin Whelan, Claire L Shovlin
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76516 (2013)
BackgroundIron deficiency anemia remains a major global health problem. Higher iron demands provide the potential for a targeted preventative approach before anemia develops. The primary study objective was to develop and validate a metric that strat
Externí odkaz:
https://doaj.org/article/e5dff53e39dc46aea04e6dafe7b14cee
Autor:
Claire L Shovlin, Gillian Angus, Richard A Manning, Grace N Okoli, Fatima S Govani, Kay Elderfield, Graeme M Birdsey, Inês G Mollet, Michael A Laffan, Francesco A Mauri
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9154 (2010)
Coagulation factor VIII (FVIII) deficiency leads to haemophilia A. Conversely, elevated plasma levels are a strong predictor of recurrent venous thromboemboli and pulmonary hypertension phenotypes in which in situ thromboses are implicated. Extrahepa
Externí odkaz:
https://doaj.org/article/1ee1cca344154c9baa88b450f4f448dd
Autor:
Ghazel Mukhtar, Claire L. Shovlin
Publikováno v:
eJHaem, Vol 4, Iss 3, Pp 602-611 (2023)
Abstract Hereditary haemorrhagic telangiectasia (HHT) can result in challenging anaemia and thrombosis phenotypes. Clinical presentations of HHT vary for relatives with identical casual mutations, suggesting other factors may modify severity. To exam
Externí odkaz:
https://doaj.org/article/294455ac894e4d7faf5ded714f437c2a
Autor:
Lakshya Sharma, Fatma Almaghlouth, Heidi Mckernan, James Springett, Hannah C. Tighe, Claire L. Shovlin
Publikováno v:
Haematologica, Vol 109, Iss 3 (2023)
Externí odkaz:
https://doaj.org/article/abea7f9fe4d44867adb93cc6b1cb3db3
Publikováno v:
BMJ Open Respiratory Research, Vol 6, Iss 1 (2019)
Introduction Assessment of performance status is an important component of clinical management of patients with pulmonary arteriovenous malformations (PAVMs). Usual methods are time-consuming and insensitive to variations within normal or supranormal
Externí odkaz:
https://doaj.org/article/b83a0790557c41dc89bd15cc7cb0e688