Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Claire L Attwooll"'
Publikováno v:
Molecular and Cellular Biology. 29:5540-5551
In this study, we examine the telomeric functions of the mammalian Mre11 complex by using hypomorphic Mre11 and Nbs1 mutants (Mre11(ATLD1/ATLD1) and Nbs1(Delta)(B/)(DeltaB), respectively). No telomere shortening was observed in Mre11(ATLD1/ATLD1) cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd014dc6600a9ecf3099b0c6647e8149
https://doi.org/10.1128/mcb.00479-09
https://doi.org/10.1128/mcb.00479-09
Autor:
Claire L Attwooll, Jennifer Varley, Mary R Thorncroft, Jillian M. Birch, Gail McGown, Fiona Stewart
Publikováno v:
Cancer Genetics and Cytogenetics. 135:165-172
The majority of families with classic Li-Fraumeni Syndrome (LFS) and a significant proportion of Li-Fraumeni-like (LFL) families have a germline mutation in the TP53 tumor suppressor gene. However around 20% of LFS and 60% of LFL families have no ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::098b776be3f6d9aefa7b308095ec3b06
https://doi.org/10.1016/s0165-4608(01)00649-5
https://doi.org/10.1016/s0165-4608(01)00649-5
Autor:
Anna Kelsey, Mary R Thorncroft, John M Boyle, Jillian M. Birch, Martin J Greaves, Gail McGown, Jennifer Varley, Gavin R M White, Claire L Attwooll
Publikováno v:
Oncogene. 20:2647-2654
Germline TP53 splicing mutations have been described infrequently (>2%) in the literature, however in a series of 40 patients and families identified by our group in which there are germline TP53 mutations, seven affect splicing (18%). The low figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4dce3b1838b3282a98970b29cd37299
https://doi.org/10.1038/sj.onc.1204369
https://doi.org/10.1038/sj.onc.1204369
Autor:
M Tariq, Nicholas Telford, Claire L Attwooll, John Coyne, Martin Harris, Brian P Eyden, Anthony J. Freemont, M Atkinson, Jennifer Varley
Publikováno v:
The American Journal of Surgical Pathology. 24:1020-1026
A case of extraskeletal myxoid chondrosarcoma (EMC) in which there was histochemical, immunohistochemical, and ultrastructural evidence of neuroendocrine differentiation is reported. Genetic investigations showed the recently described novel transloc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b3a63d5a29ea433a5eea64c9affb7c
https://doi.org/10.1097/00000478-200007000-00015
https://doi.org/10.1097/00000478-200007000-00015
Autor:
Helmut Hanenberg, Orna Levran, Kornelia Neveling, Rashida Henry, Eunike Velleuer, Jurg Ott, Kelly Milton, Reinhard Kalb, Sat Dev Batish, Sandra Barral, Paula Río, Claire L. Attwooll, Detlev Schindler, Arleen D. Auerbach, John H.J. Petrini
Publikováno v:
Nature Genetics. 37:931-933
Seven Fanconi anemia-associated proteins (FANCA, FANCB, FANCC, FANCE, FANCF, FANCG and FANCL) form a nuclear Fanconi anemia core complex that activates the monoubiquitination of FANCD2, targeting FANCD2 to BRCA1-containing nuclear foci. Cells from in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0bd1c6b1267c6ca0213ee60a28ea81a
https://doi.org/10.1038/ng1624
https://doi.org/10.1038/ng1624
Publikováno v:
Oncogene. 18:7599-7601
A proportion of extraskeletal myxoid chondrosarcomas (EMC) have been shown to have a characteristic translocation t(9;22)(q22;q12) involving the EWS gene at 22q12 and the CHN orphan nuclear receptor gene at 9q22. This translocation appears to be larg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c9671916ac75717657c1d7b8f8fc068
https://doi.org/10.1038/sj.onc.1203156
https://doi.org/10.1038/sj.onc.1203156
Publikováno v:
Journal of cellular biochemistry. 97(3)
The advent of gene targeting has allowed the dissection of many essential cellular pathways, including those involved in cell cycle regulation, signal transduction, and development. However, it is becoming increasingly clear that the simple gene dele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59325d88599c3c11821c47662fad5e5
https://pubmed.ncbi.nlm.nih.gov/16288461
https://pubmed.ncbi.nlm.nih.gov/16288461
Autor:
Reinhard Kalb, Kornelia Neveling, Claire L. Attwooll, Orna Levran, Sandra Barral, Sat Dev Batish, Paula Río, Eunike Velleuer, Kelly Milton, Arleen D. Auerbach, Jurg Ott, Helmut Hanenberg, John H.J. Petrini, Rashida Henry, Detlev Schindler
Publikováno v:
Nature Genetics. 37:1296-1296
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af38effad2b638db6fccd0db65e3eadb
https://doi.org/10.1038/ng1105-1296
https://doi.org/10.1038/ng1105-1296
Publikováno v:
Journal of Cellular Biochemistry; Feb2006, Vol. 97 Issue 3, p459-473, 15p