Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Claire Kwan"'
Autor:
Chengcheng Guo, Qunying Yang, Jiawei Li, Shaoxiong Wu, Meiling Deng, Xiaojing Du, Ke Sai, Xiaobing Jiang, Zhenghe Chen, Ji Zhang, Fuhua Lin, Jian Wang, Yinsheng Chen, Chao Ke, Xiangheng Zhang, Xue Ju, Yonggao Mou, Jeffrey Bacha, Anne Steino, Sarath Kanekal, Claire Kwan, Gregory Johnson, Richard Schwartz, John Langlands, Dennis Brown, Zhong-ping Chen
Publikováno v:
Glioma, Vol 2, Iss 4, Pp 167-173 (2019)
Background and Aim: Approximately 60% of glioblastoma multiforme (GBM) patients possess an unmethylated O-6-methylguanine-DNA methyltransferase (MGMT) gene, which confers a limited response to standard-of-care treatment with temozolomide (TMZ), resul
Externí odkaz:
https://doaj.org/article/359acf2023e44c0588f664d99a97141b
Autor:
Chengcheng Guo, Zhongping Chen, Qunying Yang, Jiawei Li, Shaoxiong Wu, Jeffery Bacha, Greg Johnson, John Langlands, Claire Kwan, Sarath Kanekal, Richard Schwartz, Dennis Brown
Publikováno v:
WFNOS 2022 Abstract Book.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3783519cf5cb5ed97205b22796017ae9
https://doi.org/10.14791/btrt.2022.10.f-2611
https://doi.org/10.14791/btrt.2022.10.f-2611
Autor:
Yinsheng Chen, Chao Ke, Richard Schwartz, Zhongping Chen, Dennis M. Brown, Qunying Yang, Xiao-Jing Du, Zhenghe Chen, Sarath Kanekal, John Langlands, Jia-wei Li, Claire Kwan, Meiling Deng, Anne Steino, Ji Zhang, Jian Wang, Shao-xiong Wu, Fuhua Lin, Yonggao Mou, Jeffrey A. Bacha, Greg A. Johnson, Xiaobing Jiang, Ke Sai, Xue Ju, Xiangheng Zhang, Chengcheng Guo
Publikováno v:
Glioma, Vol 2, Iss 4, Pp 167-173 (2019)
Background and Aim: Approximately 60% of glioblastoma multiforme (GBM) patients possess an unmethylated O-6-methylguanine-DNA methyltransferase (MGMT) gene, which confers a limited response to standard-of-care treatment with temozolomide (TMZ), resul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0397a7cfb0051bed409bf042879e57f
http://www.jglioma.com/article.asp?issn=2589-6113
http://www.jglioma.com/article.asp?issn=2589-6113
Autor:
Yingyue Xu, Claus Peter Richter, Stuart R. Stock, Xiaodong Tan, Israt Jahan, Bernd Fritzsch, Carmen Soriano, Changyow Claire Kwan, Jaime García-Añoveros, Xianghui Xiao
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports
Scientific Reports
To determine whether responses during infrared neural stimulation (INS) result from the direct interaction with spiral ganglion neurons (SGNs), we tested three genetically modified deaf mouse models: Atoh1-cre; Atoh1 f/f (Atoh1 conditional knockout,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3708f848b7841b75d262eb054aa1d6f
http://link.springer.com/article/10.1038/s41598-017-18814-9
http://link.springer.com/article/10.1038/s41598-017-18814-9
Autor:
John Langlands, Claire Kwan, Jia-wei Li, Chengcheng Guo, Richard Schwartz, Zhongping Chen, Dennis M. Brown, Qunying Yang, Shao-xiong Wu, Greg Johnson, Sarath Kanekal, Jeffrey A. Bacha
Publikováno v:
Neuro-Oncology Advances. 3:iv9-iv9
VAL-083 is a novel bi-functional DNA targeting agent that induces inter-strand DNA cross-links at N7-guanine, leading to DNA double-strand breaks and cell death. In vitro and in vivo studies have demonstrated VAL-083 circumvents MGMT-mediated chemo-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58bc66aaba6d13c805a7eaeb68780b86
https://doi.org/10.1093/noajnl/vdab112.033
https://doi.org/10.1093/noajnl/vdab112.033
Autor:
Sarath Kanekal, Gregory Johnson, Richard Schwartz, Dennis Brown, Chengcheng Guo, Claire Kwan, Qunying Yang, Anne Steino, Jeffrey A. Bacha, Zhongping Chen, Shao-xiong Wu, John Langlands, Jia-wei Li
Publikováno v:
Cancer Research. 81:CT172-CT172
Glioblastoma (GBM) is the most common and aggressive primary brain cancer. The majority of glioblastoma multiforme (GBM) patients have an unmethylated MGMT promoter status, leading to limited response to TMZ and decreased survival. Current standard-o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a383e1f68364f22c754c72b8d4dae2bd
https://doi.org/10.1158/1538-7445.am2021-ct172
https://doi.org/10.1158/1538-7445.am2021-ct172
Autor:
Lorena Lopez, Jeffrey A. Bacha, Shao-xiong Wu, Richard Schwartz, Sarath Kanekal, Greg A. Johnson, Claire Kwan, Zhongping Chen, John Langlands, Jia-wei Li, Qunying Yang, Dennis Brown, Chengcheng Guo
Publikováno v:
Neuro Oncol
Approximately 60% of glioblastoma multiforme (GBM) patients possess an unmethylated methylguanine DNA-methyltransferase (MGMT gene, which confers a limited response to standard of care treatment with temozolomide (TMZ) resulting in a lower survival.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ccd74a4d92ab4f2af359f1ead08123
https://europepmc.org/articles/PMC6847153/
https://europepmc.org/articles/PMC6847153/
Autor:
Richard Schwartz, Dennis Brown, Qunying Yang, Zhongping Chen, Chengcheng Guo, Greg Johnson, John Langlands, Anne Steino, Jia-wei Li, Shao-xiong Wu, Sarath Kanekal, Claire Kwan, Jeffrey A. Bacha, Lorena Lopez
Publikováno v:
Neuro Oncol
Approximately 60% of glioblastoma multiforme (GBM) patients possess an unmethylated methylguanine DNA-methyltransferase (MGMT) promoter region, which confers a limited response to standard-of-care treatment with temozolomide (TMZ), resulting in short
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea67e274d2d022c949a0c3f5d8a0266
https://doi.org/10.1093/neuonc/noaa215.242
https://doi.org/10.1093/neuonc/noaa215.242
Autor:
Claire Kwan, Richard Schwartz, Qunying Yang, Shao-xiong Wu, Sarath Kanekal, Gregory Johnson, Jia-Wei Lei, Anne Steino, Zhongping Chen, Dennis M. Brown, Chengcheng Guo, John Langlands, Jeffrey A. Bacha
Publikováno v:
Cancer Research. 80:CT273-CT273
Glioblastoma (GBM) is the most common and aggressive primary brain cancer. Current standard-of-care includes surgery followed by chemoirradiation and temozolomide (TMZ). An unmethylated promoter for O6-methylguanine DNA methyltransferase (MGMT) is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c2d142a30204d8efe6d55dc1a9c0d7f
https://doi.org/10.1158/1538-7445.am2020-ct273
https://doi.org/10.1158/1538-7445.am2020-ct273
Autor:
Lorena Lopez, Richard Schwartz, Zhongping Chen, Claire Kwan, Sarath Kanekal, Anne Steino, Jeffrey A. Bacha, John Langlands, Dennis Brown, Chengcheng Guo
Glioblastoma (GBM) is the most common and aggressive primary brain cancer. Current standard-of-care includes surgery followed by chemo-radiation and temozolomide. An unmethylated promoter for O6-methylguanine-DNA-methyltransferase (MGMT) is a validat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5587adfac21c02a1dc433d9135cd69d4
https://europepmc.org/articles/PMC6216509/
https://europepmc.org/articles/PMC6216509/