Supplementary Figure 1 from Fhit Regulates EMT Targets through an EGFR/Src/ERK/Slug Signaling Axis in Human Bronchial Cells

Autor: Béatrice Nawrocki-Raby, Myriam Polette, Philippe Birembaut, Véronique Dalstein, Claire Kileztky, Christine Gilles, Laurent Duca, Simon Grelet, Audrey Joannes

PDF file - 99KB, Supplementary figure 1: Cell invasion induced by Fhit is Slug-dependent. (a) Analysis of the effect of Slug siRNA 2 or a scrambled siRNA on the invasive capacities of HBE4-E6/E7 transfectants in a modified Boyden chamber invasion ass

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b8b3dc152ef83215966fd60859b39e
https://doi.org/10.1158/1541-7786.22511005.v1

New insights into spectral histopathology: infrared-based scoring of tumour aggressiveness of squamous cell lung carcinomas

Autor: Olivier Piot, Jean-François Angiboust, Claire Kileztky, Cyril Gobinet, Myriam Polette, Philippe Birembaut, Vincent Gaydou, Vincent Vuiblet

Publikováno v: Chemical Science
Chemical Science, 2019, 10 (15), pp.4246-4258. ⟨10.1039/c8sc04320e⟩
Chemical Science, The Royal Society of Chemistry, 2019, 10 (15), pp.4246-4258. ⟨10.1039/c8sc04320e⟩

International audience; Spectral histopathology, based on infrared interrogation of tissue sections, proved a promising tool for helping pathologists in characterizing histological structures in a quantitative and automatic manner. In cancer diagnosi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3168024ef4d067dd16161a2459d686
https://doi.org/10.1039/c8sc04320e

Fhit Regulates EMT Targets through an EGFR/Src/ERK/Slug Signaling Axis in Human Bronchial Cells

Autor: Philippe Birembaut, Audrey Joannes, Christine Gilles, Claire Kileztky, Myriam Polette, Simon Grelet, B. Nawrocki-Raby, Véronique Dalstein, Laurent Duca

Publikováno v: Molecular Cancer Research. 12:775-783

In many cancers, including lung carcinomas, Fragile histidine triad (Fhit) is frequently decreased or lost. Fhit status has recently been shown to be associated with elevated in vitro and in vivo invasiveness in lung cancer. Tumor cell invasion is fa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4617f255f3c28070a500478f8340a9a
https://doi.org/10.1158/1541-7786.mcr-13-0386-t

The human NANOS3 gene contributes to lung tumour invasion by inducing epithelial-mesenchymal transition

Autor: Simon, Grelet, Vanessa, Andries, Myriam, Polette, Christine, Gilles, Katrien, Staes, Anne-Pascaline, Martin, Claire, Kileztky, Christine, Terryn, Véronique, Dalstein, Chun-Wen, Cheng, Chen-Yang, Shen, Philippe, Birembaut, Frans, Van Roy, Béatrice, Nawrocki-Raby

Publikováno v: The Journal of pathology. 237(1)

We have explored the role of the human NANOS3 gene in lung tumour progression. We show that NANOS3 is over-expressed by invasive lung cancer cells and is a prognostic marker for non-small cell lung carcinomas (NSCLCs). NANOS3 gene expression is restr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1041525006af5839db33d45a64679fab
https://pubmed.ncbi.nlm.nih.gov/25904364

The E-cadherin-repressed hNanos1 gene induces tumor cell invasion by upregulating MT1-MMP expression

Autor: Claire Kileztky, K. Strumane, Christine Gilles, B. Nawrocki-Raby, Myriam Polette, F. Van Roy, Geert Berx, Véronique Dalstein, Philippe Birembaut, A. Bonnomet

Publikováno v: Oncogene. 27(26)

In this study, we examined the role of the E-cadherin-repressed gene human Nanos1 (hNanos1) in tumor invasion process. First, our in vivo study revealed that hNanos1 mRNAs were overexpressed in invasive lung carcinomas. Moreover, hNanos1 was co-local

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b9eaeccface163f7481ce105f6af495
https://pubmed.ncbi.nlm.nih.gov/18223680