Výsledky vyhledávání - "Claire J.P. Boog"

Toward a myeloablative regimen with clinical potential: II. Treosulfan induces specific skin graft tolerance across haploidentical MHC barriers

Autor: Wim Vos, Claire J.P. Boog, Robert Ploemacher, D. W J G van Breugel, M. van Pel

Publikováno v: Bone Marrow Transplantation. 33:153-159

Treosulfan is a water-soluble structural analog of busulfan, acting as a prodrug of alkylating epoxide species. It does not induce severe hepatotoxicity or veno-occlusive disease at or above the maximum tolerated dose, lacks significant nonhematologi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db2406bf88b9cc2b1f8cd7c6af1ec229
https://doi.org/10.1038/sj.bmt.1704333

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Donor-specific tolerance in a murine model: the result of extra-thymic T cell deletion?

Autor: Melissa van Pel, Jose Vingerhoed, Margot van Wijk, Danielle W.J.G. van Breugel, Claire J.P. Boog, Paul J.M. Roholl, Sacco Luypen

Publikováno v: Transplant Immunology. 11:375-384

Previously, we established a murine model, that involves the engraftment of fully allogeneic T cell depleted donor bone marrow cells in sublethally irradiated and single dose anti-CD3 treated recipient mice. These mice developed permanent stable mult

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac3fd3c6aad03633dc56c332226d441
https://doi.org/10.1016/s0966-3274(02)00157-0

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Towards a myeloablative regimen with clinical potential: I. Treosulfan conditioning and bone marrow transplantation allow induction of donor-specific tolerance for skin grafts across full MHC barriers

Autor: D. W J G van Breugel, Wim Vos, Claire J.P. Boog, M. van Pel, Robert Ploemacher

Publikováno v: Bone Marrow Transplantation. 32:15-22

To investigate whether we could create a radiation-free conditioning regimen to induce permanent mixed and multilineage chimerism and donor-specific tolerance, we treated recipient mice with anti-T-cell antibodies, varying and fractionated doses of T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79fc33aa9b40b13bdd150d3e27d7018b
https://doi.org/10.1038/sj.bmt.1704094

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High IL-13 production by human neonatal T cells: neonate immune system regulator?

Autor: Birgitta S. Breur-Vriesendorp, Claire J.P. Boog, L. C. M. Boeije, Berend Hooibrink, Lucien A. Aarden, Laura M. Ribeiro-do-Couto, Jojanneke S. Kroon

Publikováno v: European journal of immunology, 31(11), 3394-3402. Wiley-VCH Verlag

Neonates are highly susceptible to diseases and display biased type 2 immune responses, although no skewing to type 2 cytokines has been reported. In view of the emerging importance of IL-13 in type 2 inflammatory responses and clinical allergy, we a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf3a619e879bd1fd77c1838e27b6a0c
https://doi.org/10.1002/1521-4141(200111)31:11<3394::aid-immu3394>3.0.co

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Permanent acceptance of both cardiac and skin allografts using a mild conditioning regimen for the induction of stable mixed chimerism in mice

Autor: Danielle W.J.G. van Breugel, Debby Smits, Melissa van Pel, Claire J.P. Boog, Mathijs van Eck, Luuk B. Hilbrands

Publikováno v: Transplant Immunology, 11, 57-63
Transplant Immunology, 11, 1, pp. 57-63

Item does not contain fulltext Patients who are receiving an organ transplant nowadays are sentenced to the life-long administration of immunosuppressive drugs, which have serious side effects. The reliable induction of donor-specific tolerance there

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c8009aa839581446e4a8bf02c181d91
https://doi.org/10.1016/S0966-3274(02)00147-8

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Dynamics of measles virus protein expression are reflected in the MHC class I epitope display

Autor: Claire J.P. Boog, Cécile A. C. M. van Els, Martien C. M. Poelen, Ad P. J. M. de Jong, Carla A. Herberts, Jacqueline A. M. van Gaans-van den Brink, Hugo M Meiring, Ed van der Heeft

Publikováno v: Molecular immunology. 39(10)

Following measles virus (MV) infection, viral peptides are presented to CTL by MHC class I molecules on infected antigen presenting cells at widely different epitope densities. Whereas three MV epitopes (MV-M(211-219), MV-F(438-446) and MV-H(30-38))

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ee42a2013ad3578e5c4238e10af8c78
https://pubmed.ncbi.nlm.nih.gov/12431390

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