Výsledky vyhledávání - "Claire J. Guo"

Abstract 153: Development of a workflow to handle the quality control and analysis of Olink protein biomarker data in early phase oncology clinical trials

Autor: Stacie Lambert, Claire J. Guo, Mary Saltarelli, Chun Zhang, Hua Fang

Publikováno v: Cancer Research. 81:153-153

INTRODUCTION: Olink is a high-throughput targeted biomarker platform based on Proximity Extension Assay (PEA) technology using oligonucleotide-labeled antibody pairs. At AbbVie RWC, we have primarily utilized the 96-plex Immune-Oncology (IO) panel me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::71443a7e24df4700b908e49937949c05
https://doi.org/10.1158/1538-7445.am2021-153

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Abstract 4464: Pharmacodynamic and predictive biomarkers of clinical responses to PD-1 inhibitor budigalimab from the first-in-human clinical trial

Autor: Tolga Turan, David Masica, Chun Zhang, Catherine Tribouley, Gregory Vosganian, Claire J. Guo, Stefan Englert, Robert T. McLaughlin, Stacie Lambert, Daniel E. H. Afar

Publikováno v: Cancer Research. 80:4464-4464

Background: Programmed cell death 1 (PD-1) is a receptor upregulated on activated lymphocytes that mediates a dominant-negative checkpoint signal limiting antigen receptor-driven cellular activation. PD-1 immune checkpoint inhibitors have shown durab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a4f44ae785ddbac576be2421beb9f7ed
https://doi.org/10.1158/1538-7445.am2020-4464

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The source of gypsum in Mammoth Cave, Kentucky

Autor: Claire J. Guo, Aaron N. Aadison, David A. Fike, G. Robert Osburn, J. Garrecht Metzger

Publikováno v: Geology. 43:187-190

Mammoth Cave (Kentucky, USA) is the world9s longest human-navigable cave system. Gypsum (CaSO 4 ∙2H 2 O) crystals line many dry passages of the limestone cave and the source of sulfur for the gypsum remains uncertain. Previous workers have suggeste

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::775552ba7df1e37b773fdcf19ecfe136
https://doi.org/10.1130/g36131.1

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