Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Claire J H Kramer"'
Autor:
Katja N. Gaarenstroom, Claire J H Kramer, Lise M van Wijk, Tjalling Bosse, Harry Vrieling, Cor D. de Kroon, Judith R. Kroep, S. Vermeulen, Marthe M de Jonge, Natalja T. ter Haar, Maaike P.G. Vreeswijk
Publikováno v:
Cancers, 13(12), 2994. MDPI} {AG
Cancers
Cancers, Vol 13, Iss 2994, p 2994 (2021)
Cancers
Cancers, Vol 13, Iss 2994, p 2994 (2021)
Simple Summary Rapid and reliable identification of patients with homologous recombination deficient (HRD) tumors is important for treatment choice as these tumors tend to respond well to platinum-based chemotherapy and PARP inhibitors (PARPi). In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91077617985b09704101321a36dda3c2
https://hdl.handle.net/1887/3250622
https://hdl.handle.net/1887/3250622
Autor:
A Llop-Guevara, Tjalling Bosse, N. ter Haar, Violeta Serra, N Campanini, Alexandra Leary, Benedetta Pellegrino, Antonino Musolino, E Yaniz-Galende, Claire J H Kramer, Mpg Vreeswijk
Publikováno v:
Translational research biomarkers.
Introduction/Background* RAD51 protein has been proposed as a functional readout of homologous recombination (HR) status using formalin-fixed paraffin embedded (FFPE) tumour tissue blocks. Recently, few laboratories have assessed the performance of R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f08d904bf11833ee87f4769f9894bc4
https://doi.org/10.1136/ijgc-2021-esgo.592
https://doi.org/10.1136/ijgc-2021-esgo.592
Autor:
Hein Putter, Esther Bastiaannet, Gabi W. van Pelt, Emad A. Rakha, Rob A. E. M. Tollenaar, Claire J H Kramer, Wilma E. Mesker, Kiki M.H. Vangangelt, Andrew R. Green, Danielle Cohen
Publikováno v:
Breast Cancer Research and Treatment, 179(1), 37-45. SPRINGER
Breast Cancer Research and Treatment
Breast Cancer Research and Treatment
Purpose The tumour microenvironment in older patients is subject to changes. The tumour–stroma ratio (TSR) was evaluated in order to estimate the amount of intra-tumoural stroma and to evaluate the prognostic value of the TSR in older patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4ced0da57795b89ce86824ae63ad86
https://hdl.handle.net/1887/3184240
https://hdl.handle.net/1887/3184240
Autor:
R.A.E.M. Tollenaar, G W van Pelt, T.J.A. Dekker, Wilma E. Mesker, Kiki M.H. Vangangelt, Claire J H Kramer
Publikováno v:
Breast Cancer Research and Treatment
Breast Cancer Research and Treatment, 173(1), 55-64
Breast Cancer Research and Treatment, 173(1), 55-64
Purpose There is a strong need to improve the prognostication of breast cancer patients in order to prevent over- and undertreatment, especially when considering adjuvant chemotherapy. Tumour stroma characteristics might be valuable in predicting dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d54b6f807300975fd4c3e7df7c37266
http://europepmc.org/articles/PMC6394568
http://europepmc.org/articles/PMC6394568
Autor:
Lise M van Wijk, Cor D. de Kroon, Tjalling Bosse, Harry Vrieling, Claire J H Kramer, Natalja T. ter Haar, S. Vermeulen, Maaike P.G. Vreeswijk, Katja N. Gaarenstroom, Violeta Serra, Marthe M de Jonge
Publikováno v:
Cancer Research. 81:364-364
Sensitivity to PARP inhibitors is related to tumor-specific defects in homologous recombination (HR) and extends beyond BRCA1/2-related deficiencies. Therefore, there is great interest in a robust method to identify HR-deficient (HRD) carcinomas in r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::725fefffe731d17a54a9e5228617e021
https://doi.org/10.1158/1538-7445.am2021-364
https://doi.org/10.1158/1538-7445.am2021-364