Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Claire Ham"'
Autor:
Edmund G.-T. Wee, Sarah Kempster, Deborah Ferguson, Joanna Hall, Claire Ham, Susan Morris, Alison Crook, Sarah C. Gilbert, Bette Korber, Neil Almond, Tomáš Hanke
Publikováno v:
Vaccines, Vol 12, Iss 9, p 965 (2024)
During the COVID-19 pandemic, antibody-based vaccines targeting the SARS-CoV-2 spike glycoprotein were the focus for development because neutralizing antibodies were associated with protection against the SARS-CoV-2 infection pre-clinically and in hu
Externí odkaz:
https://doaj.org/article/930f60a8a56f41d685369c49147e4604
Autor:
Neil Berry, Deborah Ferguson, Sarah Kempster, Jo Hall, Claire Ham, Adrian Jenkins, Vicky Rannow, Elaine Giles, Rose Leahy, Sara Goulding, Arturo Fernandez, Yemisi Adedeji, Sandrine Vessillier, Deepa Rajagopal, Sandra Prior, Yann Le Duff, Matthew Hurley, Sarah Gilbert, Martin Fritzsche, Ryan Mate, Nicola Rose, Robert J. Francis, Kirsty MacLellan-Gibson, Alejandro Suarez-Bonnet, Simon Priestnall, Neil Almond
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract SARS-CoV-2 exhibits a diverse host species range with variable outcomes, enabling differential host susceptibility studies to assess suitability for pre-clinical countermeasure and pathogenesis studies. Baseline virological, molecular and pa
Externí odkaz:
https://doaj.org/article/0bdbc34a3c9f4aa9acf1c9f0c03b6ceb
Autor:
Neil Berry, Monja Stein, Deborah Ferguson, Claire Ham, Jo Hall, Elaine Giles, Sarah Kempster, Yemisi Adedeji, Neil Almond, Carolina Herrera
Publikováno v:
Pathogens, Vol 11, Iss 9, p 1033 (2022)
Zika virus (ZIKV) cases continue to be reported, and no vaccine or specific antiviral agent has been approved for the prevention or treatment of infection. Though ZIKV is primarily transmitted by mosquitos, cases of sexual transmission and prolonged
Externí odkaz:
https://doaj.org/article/e5e1eace77f243a2b5eacda4be2c1966
Autor:
Emmanuel Atangana Maze, Claire Ham, Jack Kelly, Lindsay Ussher, Neil Almond, Greg J. Towers, Neil Berry, Robert Belshaw
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Retroviral replication leaves a DNA copy in the host cell chromosome, which over millions of years of infection of germline cells has led to 5% of the human genome sequence being comprised of endogenous retroviruses (ERVs), distributed throughout an
Externí odkaz:
https://doaj.org/article/b6cd3d6d28024df28ce0dcd2f6258114
Autor:
Barbara Tavano, Vicky Tsipouri, Gareth A. D. Hardy, Caroline M. Royle, Michael R. Keegan, Dietmar Fuchs, Steven Patterson, Neil Almond, Neil Berry, Claire Ham, Deborah Ferguson, Adriano Boasso
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The human immunodeficiency virus (HIV) accesses the central nervous system (CNS) early during infection, leading to HIV-associated cognitive impairment and establishment of a viral reservoir. Here, we describe a dichotomy in inflammatory responses in
Externí odkaz:
https://doaj.org/article/059140a26240458491a5e6fb9961998f
Autor:
Neil Berry, Maria Manoussaka, Claire Ham, Deborah Ferguson, Hannah Tudor, Giada Mattiuzzo, Bep Klaver, Mark Page, Richard Stebbings, Atze T Das, Ben Berkhout, Neil Almond, Martin P Cranage
Publikováno v:
PLoS Pathogens, Vol 12, Iss 12, p e1006083 (2016)
In order to evaluate the role of persisting virus replication during occult phase immunisation in the live attenuated SIV vaccine model, a novel SIVmac239Δnef variant (SIVrtTA) genetically engineered to replicate in the presence of doxycycline was e
Externí odkaz:
https://doaj.org/article/ea6aed62ef594471b00b7605dc821e58
Autor:
Deborah Ferguson, Giada Mattiuzzo, Claire Ham, Richard Stebbings, Bo Li, Nicola J Rose, Edward T Mee, Deborah Smith, Mark Page, Martin P Cranage, Neil Almond, Greg J Towers, Neil J Berry
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104390 (2014)
Vaccination of Mauritian cynomolgus macaques with the attenuated nef-truncated C8 variant of SIVmac251/32H (SIVmacC8) induces early, potent protection against pathogenic, heterologous challenge before the maturation of cognate immunity. To identify p
Externí odkaz:
https://doaj.org/article/5eb92a21fe9c413e99b1cd16f88e7fd4
Autor:
Neil Berry, Claire Ham, Edward T Mee, Nicola J Rose, Giada Mattiuzzo, Adrian Jenkins, Mark Page, William Elsley, Mark Robinson, Deborah Smith, Deborah Ferguson, Greg Towers, Neil Almond, Richard Stebbings
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23092 (2011)
BackgroundLive attenuated simian immunodeficiency virus (SIV) vaccines represent the most effective means of vaccinating macaques against pathogenic SIV challenge. However, thus far, protection has been demonstrated to be more effective against homol
Externí odkaz:
https://doaj.org/article/a64fa4c38d5c4c62935da21688bc9508
Autor:
Martin Cranage, Sally Sharpe, Carolina Herrera, Alethea Cope, Mike Dennis, Neil Berry, Claire Ham, Jonathan Heeney, Naser Rezk, Angela Kashuba, Peter Anton, Ian McGowan, Robin Shattock
Publikováno v:
PLoS Medicine, Vol 5, Iss 8, p e157; discussion e157 (2008)
The rectum is particularly vulnerable to HIV transmission having only a single protective layer of columnar epithelium overlying tissue rich in activated lymphoid cells; thus, unprotected anal intercourse in both women and men carries a higher risk o
Externí odkaz:
https://doaj.org/article/20ebe69c4813446bb05877fa43b3e966
Publikováno v:
Frontiers in Human Neuroscience, Vol 18 (2024)
Identification of neuromuscular impairments in cerebral palsy (CP) is essential to providing effective treatment. However, clinical recognition of neuromuscular impairments in CP and their contribution to gait abnormalities is limited, resulting in s
Externí odkaz:
https://doaj.org/article/150f5579cde2418aa831e6e0577ce9be