Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Claire H. Stevens"'
Autor:
Neville Ng, Mauricio Castro Cabral-da-Silva, Simon Maksour, Tracey Berg, Martin Engel, Dina M. Silva, Dzung Do-Ha, Jeremy S. Lum, Sonia Sanz Muñoz, Nadia Suarez-Bosche, Claire H. Stevens, Lezanne Ooi
Publikováno v:
Translational Medicine Communications, Vol 5, Iss 1, Pp 1-10 (2020)
Abstract Background Vanishing white matter disease (VWMD) is a rare disease caused by mutations of the guanine exchange factor eIF2B. VWMD typically presents with juvenile onset, and there are few treatments for the disease. Recent progress in the fi
Externí odkaz:
https://doaj.org/article/34d00140baa14b5c9bdf71e3ab7c5644
Autor:
Flora Cheng, Alana De Luca, Alison L. Hogan, Stephanie L. Rayner, Jennilee M. Davidson, Maxinne Watchon, Claire H. Stevens, Sonia Sanz Muñoz, Lezanne Ooi, Justin J. Yerbury, Emily K. Don, Jennifer A. Fifita, Maria D. Villalva, Hannah Suddull, Tyler R. Chapman, Thomas J. Hedl, Adam K. Walker, Shu Yang, Marco Morsch, Bingyang Shi, Ian P. Blair, Angela S. Laird, Roger S. Chung, Albert Lee
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
The past decade has seen a rapid acceleration in the discovery of new genetic causes of ALS, with more than 20 putative ALS-causing genes now cited. These genes encode proteins that cover a diverse range of molecular functions, including free radical
Externí odkaz:
https://doaj.org/article/6d9d5478214e4a43b5c90d1b2ff9a16b
Autor:
Rachelle Balez, Tracey Berg, Monique Bax, Sonia Sanz Muñoz, Mauricio C. Cabral-da-Silva, Martin Engel, Dzung Do-Ha, Claire H. Stevens, Dominic Rowe, Shu Yang, Ian P. Blair, Lezanne Ooi
Publikováno v:
Stem Cell Research, Vol 42, Iss , Pp - (2020)
Dermal fibroblasts were donated by a 43 year old male patient with clinically diagnosed familial amyotrophic lateral sclerosis (ALS), carrying the SOD1E101G mutation. The induced pluripotent stem cell (iPSC) line UOWi007-A was generated using repeate
Externí odkaz:
https://doaj.org/article/dae665f88de044ac8ff397bfa9c6cdd6
Autor:
Sonia Sanz Muñoz, Rachelle Balez, Mauricio e Castro Cabral-da-Silva, Tracey Berg, Martin Engel, Monique Bax, Dzung Do-Ha, Claire H. Stevens, Mark Greenough, Ashley Bush, Lezanne Ooi
Publikováno v:
Stem Cell Research, Vol 31, Iss , Pp 227-230 (2018)
The induced pluripotent stem cell (iPSC) lines UOWi002-A and UOWi003-A were reprogrammed from dermal fibroblasts via mRNA transfection. Dermal fibroblasts from a 56 year old female caucasian familial Alzheimer's disease patient carrying A246E mutatio
Externí odkaz:
https://doaj.org/article/0cbc1736d14d4a8db79ce19b3dfc783a
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9430 (2021)
Motor neuron disease (MND) comprises a group of fatal neurodegenerative diseases with no effective cure. As progressive motor neuron cell death is one of pathological characteristics of MND, molecules which protect these cells are attractive therapeu
Externí odkaz:
https://doaj.org/article/2a9a168e8eac485c8fbf648c3857cc18
Autor:
Monique Bax, Rachelle Balez, Sonia Sanz Muñoz, Dzung Do-Ha, Claire H. Stevens, Tracey Berg, Mauricio C. Cabral-da-Silva, Martin Engel, Garth Nicholson, Shu Yang, Ian P. Blair, Lezanne Ooi
Publikováno v:
Stem Cell Research, Vol 40, Iss , Pp - (2019)
Dermal fibroblasts from a 59 year old male patient with amyotrophic lateral sclerosis (symptomatic at the time of collection), attributed to a mutation in the cyclin F gene (CCNFS621G), were reprogrammed using mRNA and microRNA-delivered OSKM factors
Externí odkaz:
https://doaj.org/article/24aceff198744133ade4e5f0a2bd9611
Autor:
Monique Bax, Jessie McKenna, Dzung Do-Ha, Claire H. Stevens, Sarah Higginbottom, Rachelle Balez, Mauricio e Castro Cabral-da-Silva, Natalie E. Farrawell, Martin Engel, Philip Poronnik, Justin J. Yerbury, Darren N. Saunders, Lezanne Ooi
Publikováno v:
Cells, Vol 8, Iss 6, p 581 (2019)
The ubiquitin proteasome system (UPS) plays an important role in regulating numerous cellular processes, and a dysfunctional UPS is thought to contribute to motor neuron disease. Consequently, we sought to map the changing ubiquitome in human iPSCs d
Externí odkaz:
https://doaj.org/article/fb3bfa9cf941450b97ac10ec0bf3e5ef
Autor:
Rachelle Balez, Claire H. Stevens, Kerstin Lenk, Simon Maksour, Kuldip Sidhu, Greg Sutherland, lezanne ooi
Background Nitrosative stress is a feature of Alzheimer’s disease, however the underlying mechanisms driving nitrosative stress and the impact of nitric oxide on neuronal function in Alzheimer’s disease is still largely unknown. Methods We analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c33ba5b371bd2c630e07b5f1fe5220c9
https://doi.org/10.21203/rs.3.rs-2257266/v1
https://doi.org/10.21203/rs.3.rs-2257266/v1
Autor:
Rabbee G. Mahmudunnabi, Dzung Do-Ha, Yusuke Yamauchi, Shu Yang, Claire H. Stevens, Ian P. Blair, Nahian Binte Aziz, Md. Shahriar A. Hossain, Yoon-Bo Shim, Muhammad J. A. Shiddiky, Mostafa Kamal Masud, Lezanne Ooi
Publikováno v:
ChemElectroChem. 7:3459-3467
Dysregulated microRNA associated pathways contribute to the pathology of neurological disorders, hence presenting themselves as a potential candidate for motor neuron disease (MND) diagnosis. Herein, we reported an enzymatic amplification‐free appr
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9430, p 9430 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Motor neuron disease (MND) comprises a group of fatal neurodegenerative diseases with no effective cure. As progressive motor neuron cell death is one of pathological characteristics of MND, molecules which protect these cells are attractive therapeu