Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Claire Grierson"'
ChipSeg: An Automatic Tool to Segment Bacterial and Mammalian Cells Cultured in Microfluidic Devices
Autor:
Irene de Cesare, Criseida G. Zamora-Chimal, Lorena Postiglione, Mahmoud Khazim, Elisa Pedone, Barbara Shannon, Gianfranco Fiore, Giansimone Perrino, Sara Napolitano, Diego di Bernardo, Nigel J. Savery, Claire Grierson, Mario di Bernardo, Lucia Marucci
Publikováno v:
ACS Omega, Vol 6, Iss 4, Pp 2473-2476 (2021)
Externí odkaz:
https://doaj.org/article/d14265a544524f38b27532d973d25878
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Whole-cell modelling is a newly expanding field that has many applications in lab experiment design and predictive drug testing. Although whole-cell model output contains a wealth of information, it is complex and high dimensional and thus hard to in
Externí odkaz:
https://doaj.org/article/73673cc520824d97a6530c78b851232a
Autor:
Joshua Rees-Garbutt, Oliver Chalkley, Sophie Landon, Oliver Purcell, Lucia Marucci, Claire Grierson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Genome engineering will one day benefit from computational tools that can design genomes with desired functions. Here the authors develop computational design-simulate-test algorithms to design minimal genomes based on the whole-cell model of Mycopla
Externí odkaz:
https://doaj.org/article/a2d27e6f513347d0a606d457b9efaf7f
Autor:
Lucia Marucci, Matteo Barberis, Jonathan Karr, Oliver Ray, Paul R. Race, Miguel de Souza Andrade, Claire Grierson, Stefan Andreas Hoffmann, Sophie Landon, Elibio Rech, Joshua Rees-Garbutt, Richard Seabrook, William Shaw, Christopher Woods
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Computer-aided design (CAD) for synthetic biology promises to accelerate the rational and robust engineering of biological systems. It requires both detailed and quantitative mathematical and experimental models of the processes to (re)design biology
Externí odkaz:
https://doaj.org/article/21234573db3648779069b4c0a12e44ef
Autor:
Joshua Rees-Garbutt, Oliver Chalkley, Sophie Landon, Oliver Purcell, Lucia Marucci, Claire Grierson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/fcb0a9f768a24f66b3f4d9ff459240f9
Autor:
Ioana M. Gherman, Lucia Marucci, Zahraa Abdallah, Claire Grierson, Thomas Gorochowski, Wei Pang
Mechanistic models have been used for centuries to describe complex interconnected processes, including biological ones. As the scope of these models has widened, so have their computational demands. This complexity can limit their suitability when r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b4b0f018965e7576b4a4b48bad0da5
https://doi.org/10.20944/preprints202209.0455.v1
https://doi.org/10.20944/preprints202209.0455.v1
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2189
Synthetic biologists engineer cells and cellular functions using design-build-test cycles; when the task is to extensively engineer entire genomes, the lack of appropriate design tools and biological knowledge about each gene in a cell can lengthen t
Publikováno v:
Essays in Biochemistry
Producing ‘designer cells’ with specific functions is potentially feasible in the near future. Recent developments, including whole-cell models, genome design algorithms and gene editing tools, have advanced the possibility of combining biologica
Autor:
Idil, Cazimoglu, Alexander P S, Darlington, Aurelija, Grigonyte, Charlotte E G, Hoskin, Juntai, Liu, Robert, Oppenheimer, Jesús A, Siller-Farfán, Claire, Grierson, Antonis, Papachristodoulou
Publikováno v:
Synthetic Biology
This article presents the experience of a team of students and academics in developing a post-graduate training program in the new field of Synthetic Biology. Our Centre for Doctoral Training in Synthetic Biology (SynBioCDT) is an initiative funded b
Autor:
Karen, Böhme, Yong, Li, Florence, Charlot, Claire, Grierson, Katia, Marrocco, Kyotaka, Okada, Michel, Laloue, Fabien, Nogué
Publikováno v:
The Plant journal : for cell and molecular biology. 40(5)
Root hairs are a major site for the uptake of water and nutrients into plants, and they form an increasingly important model system for the study of development in higher plants. We now report on the molecular genetic analysis of the srh1 mutant in A