Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Claire G. Cupples"'
Autor:
Michael Hultström, Di Peng, Mediha Becirovic Agic, Claire G. Cupples, William A. Cupples, Nicholas Mitrou
Publikováno v:
Physiological Reports, Vol 9, Iss 23, Pp n/a-n/a (2021)
Abstract Acute kidney injury (AKI) is a common perioperative complication that is associated with increased mortality. This study investigates the renal gene expression in male Long–Evans rats after prolonged anesthesia and surgery to detect molecu
Externí odkaz:
https://doaj.org/article/f60037ebe4f247cd98e95bafa2866f19
Publikováno v:
Mutation Research/Reviews in Mutation Research. 705:228-238
In model DNA, A pairs with T, and C with G. However, in vivo, the complementarity of the DNA strands may be disrupted by errors in DNA replication, biochemical modification of bases and recombination. In prokaryotic organisms, mispaired bases are rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6014005d1c08eb2a950b0a2e4964b7d
https://doi.org/10.1016/j.mrrev.2010.07.002
https://doi.org/10.1016/j.mrrev.2010.07.002
Publikováno v:
DNA Repair. 8:354-359
5-Azacytidine induces CG-to-GC transversion mutations in Escherichia coli. The results presented in this paper provide evidence that repair of the drug-induced lesions that produce these mutations involves components of both the mismatch repair and n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdb04996ba293cddb0793cc3b793907a
https://doi.org/10.1016/j.dnarep.2008.11.015
https://doi.org/10.1016/j.dnarep.2008.11.015
Publikováno v:
Biochemistry. 42:1796-1803
Trp-999 is a key residue for the action of beta-galactosidases (Escherichia coli). Several site specific substitutions (Phe, Gly, Tyr, Leu) for Trp-999 were made. Each substitution caused greatly decreased affinities for substrates and inhibitors tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea5956b6d2a29f89f6ed4498224cbcf
https://doi.org/10.1021/bi0270642
https://doi.org/10.1021/bi0270642
Publikováno v:
Mutation Research/DNA Repair. 485:331-338
Vsr mediates very short patch repair in Escherichia coli, correcting T/G mismatches caused by deamination of 5-methylcytosine to thymine. MutS and MutL, part of the post-replication mismatch repair system, stimulate VSP repair. In this study, we use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c59dbfd0c76347d6dbe84c241c70da
https://doi.org/10.1016/s0921-8777(01)00071-4
https://doi.org/10.1016/s0921-8777(01)00071-4
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 304:181-185
We have developed and tested a simple phenotypic assay which monitors C to T transition mutations at the second C of a CCAGG sequence in the lacZ gene of Escherichia coli . The assay is based on new data concerning amino acid requirements on either s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c737ff2e530fdaa25358574b83f0338
https://doi.org/10.1016/0027-5107(94)90209-7
https://doi.org/10.1016/0027-5107(94)90209-7
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biology. 32(1)
Base pair mismatches in DNA arise from errors in DNA replication, recombination, and biochemical modification of bases. Mismatches are inherently transient. They are resolved passively by DNA replication, or actively by enzymatic removal and resynthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc510da925df0b62f5f3d8f727ec12d
https://pubmed.ncbi.nlm.nih.gov/19953589
https://pubmed.ncbi.nlm.nih.gov/19953589
Autor:
Bernard A. Connolly, Claire G. Cupples, Roger J. Heinze, Luis Giron-Monzon, Sven Geisler, Alexandra Solovyova, Sarah L. Elliot, Peter Friedhoff
Publikováno v:
Nucleic Acids Research
DNA mismatch repair (MMR) and very-short patch (VSP) repair are two pathways involved in the repair of T:G mismatches. To learn about competition and cooperation between these two repair pathways, we analyzed the physical and functional interaction b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d72519307653f5391f772a59d9aa6e9
https://pubmed.ncbi.nlm.nih.gov/19474347
https://pubmed.ncbi.nlm.nih.gov/19474347
Publikováno v:
Journal of bacteriology. 191(12)
The activities of the Vsr and MutH endonucleases of Escherichia coli are stimulated by MutL. The interaction of MutL with each enzyme is enhanced in vivo by 2-aminopurine treatment and by inactivation of the mutY gene. We hypothesize that MutL recrui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318cfc5166062e378beb3f252a94e8cd
https://pubmed.ncbi.nlm.nih.gov/19376855
https://pubmed.ncbi.nlm.nih.gov/19376855