Unexpected contribution of fibroblasts to muscle lineage as a mechanism for limb muscle patterning

Autor: Joana Esteves de Lima, Cédrine Blavet, Marie-Ange Bonnin, Estelle Hirsinger, Glenda Comai, Laurent Yvernogeau, Marie-Claire Delfini, Léa Bellenger, Sébastien Mella, Sonya Nassari, Catherine Robin, Ronen Schweitzer, Claire Fournier-Thibault, Thierry Jaffredo, Shahragim Tajbakhsh, Frédéric Relaix, Delphine Duprez

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)

The dogma is that limb muscle cells originate from somite, while connective tissue fibroblasts derive from lateral plate mesoderm. Here the authors identify a fibroblast population that undergoes myoblast conversion in response to BMP and contributes

Externí odkaz: https://doaj.org/article/426e99df6c074d7ca470fa9110de9340

BMP signalling directs a fibroblast-to-myoblast conversion at the connective tissue/muscle interface to pattern limb muscles

Autor: Frédéric Relaix, Glenda Comai, Marie-Ange Bonnin, Léa Bellenger, Sonya Nassari, Laurent Yvernogeau, Catherine Robin, Shahragim Tajbakhsh, Joana Esteves de Lima, Delphine Duprez, Cédrine Blavet, Sébastien Mella, Estelle Hirsinger, Ronen Schweitzer, Claire Fournier-Thibault

Positional information driving limb muscle patterning is contained in lateral plate mesoderm-derived tissues, such as tendon or muscle connective tissue but not in myogenic cells themselves. The long-standing consensus is that myogenic cells originat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b7541ee8d654a32e816fb7896987826
https://hal.archives-ouvertes.fr/hal-03002436/document

Non-myogenic Contribution to Muscle Development and Homeostasis: The Role of Connective Tissues

Autor: Delphine Duprez, Sonya Nassari, Claire Fournier-Thibault

Publikováno v: Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, 2017, 1, pp.22-22. ⟨10.3389/fcell.2017.00022⟩
Frontiers in Cell and Developmental Biology, Frontiers media, 2017, 1, pp.22-22. ⟨10.3389/fcell.2017.00022⟩

International audience; Skeletal muscles belong to the musculoskeletal system, which is composed of bone, tendon, ligament and irregular connective tissue, and closely associated with motor nerves and blood vessels. The intrinsic molecular signals re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ba769953cbdd34e87b46348c224ad9
https://hal.sorbonne-universite.fr/hal-01539045

SDF1-CXCR4 signaling: A new player involved in DiGeorge/22q11-deletion syndrome

Autor: Jean-Loup Duband, Claire Fournier-Thibault, Sophie Escot

Publikováno v: RARE DISEASES
RARE DISEASES, 2016, 4 (1), pp.e1195050. ⟨10.1080/21675511.2016.1195050⟩
Rare Diseases

International audience; The DiGeorge/22q11- deletion syndrome (22q11DS), also known as velocardiofacial syndrome, is a congenital disease causing numerous structural and behavioral disorders, including cardiac outflow tract anomalies, craniofacial dy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a9bb21d6dd39fc903dedfc37ae8c10
https://hal.archives-ouvertes.fr/hal-01538321

Sonic Hedgehog Regulates Integrin Activity, Cadherin Contacts, and Cell Polarity to Orchestrate Neural Tube Morphogenesis

Autor: Jean-Loup Duband, Sólveig Thorsteinsdóttir, Cédrine Blavet, Fernanda Bajanca, Claire Fournier-Thibault, Artem Jarov

Publikováno v: The Journal of Neuroscience. 29:12506-12520

In vertebrates, the embryonic nervous system is shaped and patterned by a series of temporally and spatially regulated cell divisions, cell specifications, and cell adhesions and movements. Morphogens of the Hedgehog, Wnt, and bone morphogenetic prot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1f6619a55abd4a153b212ff9009aab1
https://doi.org/10.1523/jneurosci.2003-09.2009