Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Claire F Jessup"'
Autor:
Heshan Peiris, Michael D Duffield, Joao Fadista, Claire F Jessup, Vinder Kashmir, Amanda J Genders, Sean L McGee, Alyce M Martin, Madiha Saiedi, Nicholas Morton, Roderick Carter, Michael A Cousin, Alexandros C Kokotos, Nikolay Oskolkov, Petr Volkov, Tertius A Hough, Elizabeth M C Fisher, Victor L J Tybulewicz, Jorge Busciglio, Pinar E Coskun, Ann Becker, Pavel V Belichenko, William C Mobley, Michael T Ryan, Jeng Yie Chan, D Ross Laybutt, P Toby Coates, Sijun Yang, Charlotte Ling, Leif Groop, Melanie A Pritchard, Damien J Keating
Publikováno v:
PLoS Genetics, Vol 12, Iss 5, p e1006033 (2016)
Type 2 diabetes (T2D) is a complex metabolic disease associated with obesity, insulin resistance and hypoinsulinemia due to pancreatic β-cell dysfunction. Reduced mitochondrial function is thought to be central to β-cell dysfunction. Mitochondrial
Externí odkaz:
https://doaj.org/article/55d1108814ad40e3b162e4623311cfe8
Autor:
Kay K. Myo Min, Darling Rojas-Canales, Daniella Penko, Mark DeNichilo, Michaelia P. Cockshell, Charlie B. Ffrench, Emma J. Thompson, Olof Asplund, Christopher J. Drogemuller, Rashmi B. Prasad, Leif Groop, Shane T. Grey, Helen E. Thomas, Thomas Loudovaris, Thomas W. Kay, My G. Mahoney, Claire F. Jessup, P. Toby Coates, Claudine S. Bonder
Publikováno v:
Cell Death and Disease, Vol 13, Iss 10, Pp 1-15 (2022)
Abstract Type 1 diabetes is a complex disease characterized by the lack of endogenous insulin secreted from the pancreatic β-cells. Although β-cell targeted autoimmune processes and β-cell dysfunction are known to occur in type 1 diabetes, a compl
Externí odkaz:
https://doaj.org/article/afcc41530a1443548bde1470cff8d8ab
Autor:
Kay K. Myo Min, Charlie B. Ffrench, Claire F. Jessup, Mia Shepherdson, Savio George Barreto, Claudine S. Bonder
Simple Summary: Pancreatic ductal adenocarcinoma (PDAC) is the most common form of pancreatic tumours, representing greater than 90% of all diagnosed cases of pancreatic cancer. PDAC has the lowest 5-year survival rate of all tumour malignancies with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6844cce43812e67e43dff069356a8c17
https://hdl.handle.net/11541.2/34061
https://hdl.handle.net/11541.2/34061
Autor:
Claire F. Jessup, Alyce M. Martin, Damien J. Keating, Waliul I. Khan, Emily W. Sun, Geraint B. Rogers, Amanda J. Page, Gregory R. Steinberg, Steven Lodewyk Wesselingh, Jocelyn M. Choo, Julian M. Yabut
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
The gut microbiome is an established regulator of aspects of host metabolism, such as glucose handling. Despite the known impacts of the gut microbiota on host glucose homeostasis, the underlying mechanisms are unknown. The gut microbiome is also a p
Autor:
Claire F. Jessup, Richard L. Young, Alyce M. Martin, Nick J. Spencer, Damien J. Keating, Geraint B. Rogers, Lex E. X. Leong
Publikováno v:
Endocrinology. 158:1049-1063
Serotonin (5-hydroxytryptamine or 5-HT) is a multifunctional bioamine with important signaling roles in a range of physiological pathways. Almost all of the 5-HT in our bodies is synthesized in specialized enteroendocrine cells within the gastrointes
Autor:
Heshan Peiris, Claudine S. Bonder, Rainer Viktor Haberberger, Patrick T. Coates, Kate A. Parham, Stuart M. Pitson, Shane T. Grey, Kay Khine Myo Min, Damien J. Keating, Claire F. Jessup, Darling Rojas-Canales, Daniella Penko, Chris Drogemuller
Publikováno v:
Diabetes. 66:1301-1311
Pancreatic islet transplantation is a promising clinical treatment for type 1 diabetes, but success is limited by extensive -cell death in the immediate posttransplant period and impaired islet function in the longer term. Following transplantation,
Publikováno v:
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility SocietyREFERENCES. 32(8)
Background Enterochromaffin (EC) cells are specialized enteroendocrine cells lining the gastrointestinal (GI) tract and the source of almost all serotonin (5-hydroxytryptamine; 5-HT) in the body. Gut-derived 5-HT has a plethora of physiological roles
Autor:
Richard L. Young, Damien J. Keating, Nick J. Spencer, Lex E. X. Leong, Geraint B. Rogers, Alyce M. Martin, Claire F. Jessup
Serotonin (5-hydroxytryptamine, 5-HT) is an important multifunctional bioamine, with roles in a range of physiological pathways. Almost all of the 5-HT in our body, and all of the circulating 5-HT, is synthesized and secreted by specialized enteroend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8085b88f5e4be30e224c9622eb945928
https://doi.org/10.1016/b978-0-12-800050-2.00007-3
https://doi.org/10.1016/b978-0-12-800050-2.00007-3
Autor:
D. Bennett Grinsfelder, Ngoc Uyen Nhi Nguyen, Hesham A. Sadek, Valentina Parra, Christi Hull, Beverly A. Rothermel, Matthew J. Watt, Claire F. Jessup, Jana S. Burchfield, Tanvi Jakkampudi, Misook Oh, Alyce M. Martin, Rana K. Gupta, Dusan Matusica, D. Randy McMillan, Damien J. Keating, Israel Iyoke, David Rotter, Melanie April Pritchard, Heshan Peiris, Aldons J. Lusis, Cyndi R. Morales, Brian W. Parks
Publikováno v:
EMBO reports. 19
Increasing non‐shivering thermogenesis (NST), which expends calories as heat rather than storing them as fat, is championed as an effective way to combat obesity and metabolic disease. Innate mechanisms constraining the capacity for NST present a f
Publikováno v:
Curr Diab Rep
PURPOSES OF REVIEW: Scattered throughout the pancreas, the endocrine islets rely on neurovascular support for signal relay to regulate hormone secretion and for maintaining tissue homeostasis. The islet accessory cells (or components) of neurovascula