Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Claire Edgerly"'
Autor:
Jonathan W. Riess, Shaila Rahman, Waleed Kian, Claire Edgerly, Andreas M. Heilmann, Russell Madison, Shakti H. Ramkissoon, Shai Shlomi Klaitman, Jon H. Chung, Sally E. Trabucco, Dexter X. Jin, Brian M. Alexander, Samuel J. Klempner, Lee A. Albacker, Garrett M. Frampton, Laila C. Roisman, Vincent A. Miller, Jeffrey S. Ross, Alexa B. Schrock, Jeffrey P. Gregg, Nir Peled, Ethan S. Sokol, Siraj M. Ali
Publikováno v:
Translational Oncology, Vol 14, Iss 10, Pp 101184- (2021)
Background: The translocation t(15:19) produces the oncogenic BRD4-NUT fusion which is pathognomonic for NUT carcinoma (NC), which is a rare, but extremely aggressive solid tumor. Comprehensive genomic profiling (CGP) by hybrid-capture based next gen
Externí odkaz:
https://doaj.org/article/f78f81cbdd204e1789f4f2191a1fc032
Autor:
Douglas I. Lin, Nikunj Shah, Julie Y. Tse, Jonathan K. Killian, Amanda Hemmerich, Claire Edgerly, James Haberberger, Eric A. Severson, Richard S.P. Huang, Shakti H. Ramkissoon, Jo-Anne Vergilio, Jeffrey S. Ross, Julia A. Elvin
Publikováno v:
Gynecologic Oncology Reports, Vol 34, Iss , Pp 100652- (2020)
Mesonephric carcinoma is a rare cancer that most often arises within the cervix, and less frequently, in the ovary and endometrium. A retrospective search of our CLIA-certified and CAP-accredited reference molecular laboratory database (Foundation Me
Externí odkaz:
https://doaj.org/article/084d9ff953d44eab8571217dce0682cc
Autor:
Lori A. Ramkissoon, Worthy Pegram, James Haberberger, Natalie Danziger, Glenn Lesser, Roy Strowd, Sonika Dahiya, Thomas J. Cummings, Wenya Linda Bi, Malak Abedalthagafi, Pratheesh Sathyan, Kimberly McGregor, Prasanth Reddy, Eric Severson, Erik Williams, Douglas Lin, Claire Edgerly, Richard S. P. Huang, Amanda Hemmerich, James Creeden, Charlotte Brown, Jeffrey Venstrom, Priti Hegde, Jeffrey S. Ross, Brian M. Alexander, Julia Elvin, Shakti H. Ramkissoon
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Despite advances in systemic therapies for solid tumors, the development of brain metastases remains a significant contributor to overall cancer mortality and requires improved methods for diagnosing and treating these lesions. Similarly, the prognos
Externí odkaz:
https://doaj.org/article/d0714fbac5434bd29958cf5481928aff
Autor:
Jonathan Keith Killian, Julie Y. Tse, Shakti H. Ramkissoon, Julia A. Elvin, James Haberberger, Richard S.P. Huang, Priti Hegde, Naomi L Ferguson, Matthew Hiemenz, Clarence Owens, Amanda Hemmerich, Jeffrey S. Ross, Brian M. Alexander, Erik A. Williams, Eric Allan Severson, Claire Edgerly, Jeffrey M. Venstrom, Jo-Anne Vergilio, Daniel L. Duncan, Douglas I. Lin, Natalie Danziger
Publikováno v:
Modern Pathology. 34:252-263
PD-L1 immunohistochemistry (IHC) currently has the most Food and Drug Administration (FDA) approvals as a companion diagnostic (CDx) for immunotherapies in specific tumor types; however, multiple other immunotherapy biomarkers exist. We performed thi
Autor:
Amanda Hemmerich, Claire Edgerly, Eric Allan Severson, Meghan Shea, Jeffrey S. Ross, Yamicia D. Connor, Jonathan L. Hecht, Daniel Duncan, Julia A. Elvin, Richard S.P. Huang, Siraj M. Ali, Douglas I. Lin, Shakti H. Ramkissoon, Jo-Anne Vergilio
Publikováno v:
Gynecologic Oncology. 157:357-366
Objective Genomic alterations of BCOR via ZC3H7B-BCOR fusion or BCOR internal tandem duplication (ITD) define a subset of endometrial stromal sarcoma (ESS). The goals of this study were to: 1) determine the molecular landscape of BCOR-rearranged ESS,
Autor:
Evgeny Yakirevich, Garrett M. Frampton, Claire Edgerly, Russell Madison, Arjun Vasant Balar, Shridar Ganesan, Jeffrey S. Ross, Alexa B. Schrock, Saranya Akumalla, Douglas I. Lin, Vincent A. Miller, Margaret Rosenzweig, Rachel L. Erlich, Siraj M. Ali
Publikováno v:
Oncology. 98:905-912
Purpose: Perivascular epithelioid cell tumor (PEComa) is a rare mesenchymal soft tissue neoplasm often linked to mTOR pathway activation via TSC2 mutation. We analyzed a series of 31 consecutive metastatic PEComa (mPEComa) cases using a combined DNA/
Autor:
Claire Edgerly, Sergey Gorelyshev, Amanda Hemmerich, Eric Allan Severson, Yakov Chudnovsky, David E. Kram, Rachel L. Erlich, Joshua McCorkle, Alexander Savateev, Nicholas Britt, Daniel Duncan, Yuri Trunin, Jeffrey S. Ross, Andge Valiakhmetova, Andrew Rankin, Richard S.P. Huang, Vincent A. Miller, Shakti H. Ramkissoon, Julia A. Elvin, Alexander Konovalov
Publikováno v:
The Oncologist
For pediatric patients with high‐grade gliomas, standard‐of‐care treatment includes surgery, chemotherapy, and radiation therapy; however, most patients ultimately succumb to their disease. With advances in genomic characterization of pediatric
Autor:
Sally E. Trabucco, Shakti H. Ramkissoon, Brian M. Alexander, Andreas M. Heilmann, Jonathan W. Riess, Nir Peled, Shaila Rahman, Samuel J. Klempner, Jon Chung, Vincent A. Miller, Dexter X. Jin, Jeffrey S. Ross, Jeffrey P. Gregg, Alexa B. Schrock, Laila C. Roisman, Garrett M. Frampton, Lee A. Albacker, Russell Madison, Claire Edgerly, Siraj M. Ali, Ethan Sokol, Waleed Kian, Shai Shlomi Klaitman
Publikováno v:
Translational Oncology, Vol 14, Iss 10, Pp 101184-(2021)
Translational Oncology
Translational Oncology
Highlights • NUT carcinoma is a rare but aggressive solid tumor that can be diagnosed by presence of the BRD4-NUT fusion. • This series presents 31 cases of solid tumors that harbor BRD4-NUT but often carry other diagnoses such NSCLC—NOS and NS
Autor:
Eric A Severson, James Haberberger, Amanda Hemmerich, Richard S P Huang, Claire Edgerly, Kelsie Schiavone, Adib Najafian, Matthew Hiemenz, Mirna Lechpammer, Jo-Anne Vergilio, Glenn Lesser, Roy Strowd, Julia Elvin, Jeffrey S Ross, Priti Hegde, Brian Alexander, Samuel Singer, Shakti Ramkissoon
Publikováno v:
The oncologist.
Background B-cell primary central nervous system (CNS) lymphoma (PCL) is diffuse large B-cell lymphoma (DLBCL) confined to the CNS. Less than 50% of patients with PCL achieve complete remission with current therapies. We describe the findings from co
Autor:
Brian M. Alexander, Charlotte Brown, Douglas I. Lin, Deborah L. McEwan, N. Lynn Ferguson, Pratheesh Sathyan, Shakti H. Ramkissoon, Prasanth Reddy, Jeffrey S. Ross, Samantha Morley, Richard S.P. Huang, Amanda Hemmerich, Erik A. Williams, Jonathan Keith Killian, Garrett M. Frampton, Jeffrey M. Venstrom, Clarence Owens, Oliver Holmes, James Haberberger, Natalie Danziger, Rachel Anhorn, Jo-Anne Vergilio, Michael B. Cohen, Julia A. Elvin, Eric Allan Severson, Claire Edgerly, Kimberly McGregor, Daniel L. Duncan
Publikováno v:
Pathology and Oncology Research
Comprehensive genomic profiling (CGP) and immunohistochemistry (IHC) are important biomarker tools used for patients with non-small cell lung cancer (NSCLC) given the expanding number of standard-of-care therapies that require companion diagnostic te